Colorimetric phage-based assay for detection of rifampin-resistant Mycobacterium tuberculosis.
Ruth
McNerney
;
Kim
Mallard
;
Honorathy MR
Urassa
;
Eshetu
Lemma
;
Helen D
Donoghue
;
(2007)
Colorimetric phage-based assay for detection of rifampin-resistant Mycobacterium tuberculosis.
Journal of clinical microbiology, 45 (4).
pp. 1330-1332.
ISSN 0095-1137
DOI: 10.1128/JCM.02028-06
Tests based on bacteriophage replication enable rapid screening of Mycobacterium tuberculosis for drug resistance. We describe a novel broth-based colorimetric method for detecting phage replication. When clinical isolates were tested by this novel method, high concordance was observed with both the traditional phage assay and gene mutation analysis for detection of resistance to rifampin.
| Item Type | Article |
|---|---|
| ISI | 245779300043 |
| Date Deposited | 17 Oct 2011 18:00 |
Explore Further
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865820 (OA Location)
- 10.1128/JCM.02028-06 (DOI)
- 17301279 (PubMed)