Items where Author or Contributor is "Croft, SL"

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Number of items: 174.

2019

Van Bocxlaer, Katrien; Caridha, Diana; Black, Chad; Vesely, Brian; Leed, Susan; Sciotti, Richard J; Wijnant, Gert-Jan; Yardley, Vanessa; Braillard, Stéphanie; Mowbray, Charles E; +2 more... Ioset, Jean-Robert; Croft, Simon L; (2019) Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis. International Journal for Parasitology: Drugs and Drug Resistance. ISSN 2211-3207 DOI: https://doi.org/10.1016/j.ijpddr.2019.02.002
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2018

Ashwin, Helen; Seifert, Karin; Forrester, Sarah; Brown, Najmeeyah; MacDonald, Sandy; James, Sally; Lagos, Dimitris; Timmis, Jon; Mottram, Jeremy C; Croft, Simon L; +1 more... Kaye, Paul M; (2018) Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis. Wellcome open research, 3. p. 135. DOI: https://doi.org/10.12688/wellcomeopenres.14867.2
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Burza, S; Croft, SL; Boelaert, M; (2018) Leishmaniasis. Elsevier. DOI: https://doi.org/10.1016/S0140-6736(18)31204-2 Full text not available from this repository.

Van Bocxlaer, K; Gaukel, E; Hauser, D; Park, SH; Schock, S; Yardley, V; Randolph, R; Plattner, JJ; Merchant, T; Croft, SL; +2 more... Jacobs, RT; Wring, SA; (2018) Topical treatment for cutaneous leishmaniasis - dermato-pharmacokinetic led optimisation of benzoxaboroles. Antimicrobial agents and chemotherapy. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02419-17
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Wijnant, GJ; (2018) New pharmacokinetic and PK/PD drug development methodologies for cutaneous leishmaniasis. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04651224
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Wijnant, GJ; Van Bocxlaer, K; Yardley, V; Harris, A; Alavijeh, M; Silva-Pedrosa, R; Antunes, S; Mauricio, I; Murdan, S; Croft, SL; (2018) Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome® and AmBisome® in murine cutaneous leishmaniasis. International journal for parasitology Drugs and drug resistance, 8 (2). pp. 223-228. ISSN 2211-3207 DOI: https://doi.org/10.1016/j.ijpddr.2018.04.001
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2017

Baker, DA; Stewart, LB; Large, JM; Bowyer, PW; Ansell, KH; Jiménez-Díaz, MB; El Bakkouri, M; Birchall, K; Dechering, KJ; Bouloc, NS; +19 more... Coombs, PJ; Whalley, D; Harding, DJ; Smiljanic-Hurley, E; Wheldon, MC; Walker, EM; Dessens, JT; Lafuente, MJ; Sanz, LM; Gamo, FJ; Ferrer, SB; Hui, R; Bousema, T; Angulo-Barturén, I; Merritt, AT; Croft, SL; Gutteridge, WE; Kettleborough, CA; Osborne, SA; (2017) A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. Nature communications, 8 (1). p. 430. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-017-00572-x
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Basilico, N; Parapini, S; Sparatore, A; Romeo, S; Misiano, P; Vivas, L; Yardley, V; Croft, SL; Habluetzel, A; Lucantoni, L; +8 more... Renia, L; Russell, B; Suwanarusk, R; Nosten, F; Dondio, G; Bigogno, C; Jabes, D; Taramelli, D; (2017) In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial. Molecules (Basel, Switzerland), 22 (12). ISSN 1420-3049 DOI: https://doi.org/10.3390/molecules22122102
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Burrell-Saward, H; Harris, AJ; de LaFlor, R; Sallam, H; Alavijeh, MS; Ward, TH; Croft, SL; (2017) Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human african trypanosomiasis. International journal of antimicrobial agents, 50 (2). pp. 203-209. ISSN 0924-8579 DOI: https://doi.org/10.1016/j.ijantimicag.2017.01.038
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2016

Cameron, MM; Acosta-Serrano, A; Bern, C; Boelaert, M; den Boer, M; Burza, S; Chapman, LA; Chaskopoulou, A; Coleman, M; Courtenay, O; +21 more... Croft, S; Das, P; Dilger, E; Foster, G; Garlapati, R; Haines, L; Harris, A; Hemingway, J; Hollingsworth, TD; Jervis, S; Medley, G; Miles, M; Paine, M; Picado, A; Poché, R; Ready, P; Rogers, M; Rowland, M; Sundar, S; de Vlas, SJ; Weetman, D; (2016) Understanding the transmission dynamics of Leishmania donovani to provide robust evidence for interventions to eliminate visceral leishmaniasis in Bihar, India. Parasites & vectors, 9 (1). p. 25. ISSN 1756-3305 DOI: https://doi.org/10.1186/s13071-016-1309-8
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Hendrickx, S; Guerin, PJ; Caljon, G; Croft, SL; Maes, L; (2016) Evaluating drug resistance in visceral leishmaniasis: the challenges. Parasitology, 145 (4). pp. 453-463. ISSN 0031-1820 DOI: https://doi.org/10.1017/S0031182016002031
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Tegazzini, D; Díaz, R; Aguilar, F; Peña, I; Presa, JL; Yardley, V; Martin, JJ; Coteron, JM; Croft, SL; Cantizani, J; (2016) A replicative in vitro assay for drug discovery against Leishmania donovani. Antimicrobial agents and chemotherapy, 60 (6). pp. 3524-32. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01781-15
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Van Bocxlaer, K; Yardley, V; Murdan, S; Croft, SL; (2016) Drug permeation and barrier damage in Leishmania-infected mouse skin. The Journal of antimicrobial chemotherapy, 71 (6). pp. 1578-85. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkw012 Full text not available from this repository.

Van Bocxlaer, K; Yardley, V; Murdan, S; Croft, SL; (2016) Topical formulations of miltefosine for cutaneous leishmaniasis in a BALB/c mouse model. The Journal of pharmacy and pharmacology, 68 (7). pp. 862-72. ISSN 0022-3573 DOI: https://doi.org/10.1111/jphp.12548
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Xu, J; Bergquist, R; Qian, YJ; Wang, Q; Yu, Q; Peeling, R; Croft, S; Guo, JG; Zhou, XN; (2016) China-Africa and China-Asia Collaboration on Schistosomiasis Control: A SWOT Analysis. Adv Parasitol, 92. pp. 435-66. ISSN 2163-6079 DOI: https://doi.org/10.1016/bs.apar.2016.02.005 Full text not available from this repository.

2015

Croft, SL; Buffett, P; (2015) Leishmaniasis. In: Goldman, L; Schafer, AI, (eds.) Goldman’s Cecil Medicine, 25th ed. Elsevier-Saunders, pp. 2120-2025. http://researchonline.lshtm.ac.uk/id/eprint/2950079 Full text not available from this repository.

Croft, SL; Ward, S; (2015) The Nobel Prize in Medicine 2015: Two drugs that changed global health. Science translational medicine, 7 (316). 316ed14. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aad5868 Full text not available from this repository.

Kaur, H; Seifert, K; Hawkes, GE; Coumbarides, GS; Alvar, J; Croft, SL; (2015) Chemical and Bioassay Techniques to Authenticate Quality of the Anti-Leishmanial Drug Miltefosine. The American journal of tropical medicine and hygiene, 92 (6 Supp). pp. 31-8. ISSN 0002-9637 DOI: https://doi.org/10.4269/ajtmh.14-0586
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Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C; (2015) Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. Gene therapy, 22 (8). pp. 628-35. ISSN 0969-7128 DOI: https://doi.org/10.1038/gt.2015.35
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Seifert, K; Juhls, C; Salguero, FJ; Croft, SL; (2015) Sequential chemo-immunotherapy of experimental visceral leishmaniasis using single low dose liposomal amphotericin B and a novel DNA vaccine candidate. Antimicrobial agents and chemotherapy, 59 (9). pp. 5819-23. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00273-15 Full text not available from this repository.

2014

Barrett, MP; Croft, SL; (2014) Emerging paradigms in anti-infective drug design. Parasitology, 141 (1). pp. 1-7. ISSN 0031-1820 DOI: https://doi.org/10.1017/S0031182013001224
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Das, S; Freier, A; Boussoffara, T; Das, S; Oswald, D; Losch, FO; Selka, M; Sacerdoti-Sierra, N; Schönian, G; Wiesmüller, KH; +10 more... Seifert, K; Schroff, M; Juhls, C; Jaffe, CL; Roy, S; Das, P; Louzir, H; Croft, SL; Modabber, F; Walden, P; (2014) Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. Science translational medicine, 6 (234). 234ra56. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.3008222 Full text not available from this repository.

Ganguly, NK; Croft, S; Singh, L; Sinha, S; Balganesh, T; (2014) Biomedicine and biotechnology: public health impact. BioMed research international, 2014. p. 524785. ISSN 2314-6133 DOI: https://doi.org/10.1155/2014/524785
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Lamour, SD; Veselkov, KA; Posma, JM; Giraud, E; Rogers, ME; Croft, S; Marchesi, JR; Holmes, E; Seifert, K; Saric, J; (2014) Metabolic, Immune, and Gut Microbial Signals Mount a Systems Response to Leishmania major Infection. Journal of proteome research, 14 (1). pp. 318-329. ISSN 1535-3893 DOI: https://doi.org/10.1021/pr5008202 Full text not available from this repository.

Sanderson, L; Yardley, V; Croft, SL; (2014) Activity of anti-cancer protein kinase inhibitors against Leishmania spp. The Journal of antimicrobial chemotherapy. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dku069 Full text not available from this repository.

2013

Ahmed, A; Ginn, C; Croft, SL; Brocchini, S; (2013) Anti-infectives. In: Uchegbu, IF; Schätzlein, AG; Cheng, WP; Lalatsa, A, (eds.) Fundamentals of Pharmaceutical Nanoscience. Springer Science,, New York, pp. 429-464. ISBN 978-1-4614-9164-4 http://researchonline.lshtm.ac.uk/id/eprint/2961949 Full text not available from this repository.

Alvar, J; Croft, SL; Kaye, P; Khamesipour, A; Sundar, S; Reed, SG; (2013) Case study for a vaccine against leishmaniasis. Vaccine, 31. B244-B249. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2012.11.080 Full text not available from this repository.

Dellai, A; Appel, J; Bouraoui, A; Croft, S; Nefzi, A; (2013) Antimalarial and cytotoxic activities of chiral triamines. Bioorganic & medicinal chemistry letters, 23 (16). pp. 4579-4582. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2013.06.035 Full text not available from this repository.

Maes, L; Cos, P; Croft, SL; (2013) The relevance of susceptibility tests, breakpoints and markers. In: Pont-Sucre, A; Diaz, E; Padron-Nieves, M, (eds.) Drug resistance in Leishmania parasites. Springer-Verlag, Wien, pp. 407-429. http://researchonline.lshtm.ac.uk/id/eprint/2939183 Full text not available from this repository.

Mohamed-Ahmed, AHA; Les, KA; Seifert, K; Croft, SL; Brocchini, S; (2013) Noncovalent Connplexation of Amphotericin-B with Poly(alpha-glutamic acid). Molecular pharmaceutics, 10 (3). pp. 940-950. ISSN 1543-8384 DOI: https://doi.org/10.1021/mp300339p Full text not available from this repository.

Mohamed-Ahmed, AbeerHA; Seifert, Karin; Yardley, Vanessa; Burrell-Saward, Hollie; Brocchini, Stephen; Croft, SimonL; (2013) Antileishmanial Activity, Uptake, and Biodistribution of an Amphotericin B and Poly(alpha-Glutamic Acid) Complex. Antimicrobial agents and chemotherapy, 57 (10). pp. 4608-4614. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02343-12 Full text not available from this repository.

2012

Barrett, MP; Croft, SL; (2012) Management of trypanosomiasis and leishmaniasis. British medical bulletin, 104. pp. 175-96. ISSN 0007-1420 DOI: https://doi.org/10.1093/bmb/lds031
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Croft, SL; Duparc, S; Arbe-Barnes, SJ; Craft, JC; Shin, CS; Fleckenstein, L; Borghini-Fuhrer, I; Rim, HJ; (2012) Review of pyronaridine anti-malarial properties and product characteristics. Malaria journal, 11. p. 270. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-11-270
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Mohamed-Ahmed, AH; Brocchini, S; Croft, SL; (2012) Recent advances in development of amphotericin B formulations for the treatment of visceral leishmaniasis. Current opinion in infectious diseases, 25 (6). pp. 695-702. ISSN 0951-7375 DOI: https://doi.org/10.1097/QCO.0b013e328359eff2 Full text not available from this repository.

Peña, S; Scarone, L; Manta, E; Stewart, L; Yardley, V; Croft, S; Serra, G; (2012) Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. Bioorganic & medicinal chemistry letters, 22 (15). pp. 4994-7. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.06.028 Full text not available from this repository.

2011

Baschong, W; Wittlin, S; Inglis, KA; Fairlamb, AH; Croft, SL; Kumar, TRS; Fidock, DA; Brun, R; (2011) Triclosan is minimally effective in rodent malaria models. Nature medicine, 17 (1). pp. 33-34. ISSN 1078-8956 DOI: https://doi.org/10.1038/nm0111-33 Full text not available from this repository.

Croft, SL; Olliaro, P; (2011) Leishmaniasis chemotherapy-challenges and opportunities. Clinical microbiology and infection, 17 (10). pp. 1478-83. ISSN 1198-743X DOI: https://doi.org/10.1111/j.1469-0691.2011.03630.x Full text not available from this repository.

Jeganathan, S; Sanderson, L; Dogruel, M; Rodgers, J; Croft, S; Thomas, SA; (2011) The Distribution of Nifurtimox Across the Healthy and Trypanosome-Infected Murine Blood-Brain and Blood-Cerebrospinal Fluid Barriers. The Journal of pharmacology and experimental therapeutics, 336 (2). pp. 506-515. ISSN 0022-3565 DOI: https://doi.org/10.1124/jpet.110.172981 Full text not available from this repository.

Seifert, K; Munday, J; Syeda, T; Croft, SL; (2011) In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. The Journal of antimicrobial chemotherapy, 66 (4). pp. 850-4. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkq542 Full text not available from this repository.

2010

Croft, SL; Seifert, K; (2010) Antiprotozoal agents. In: Finch, RogerG; Greenwood, David; Whitley, RichardJ; Norrby, SRagnar, (eds.) Antibiotic and Chemotherapy: Expert Consult (9th Edition). Saunders. ISBN 0702040649 http://researchonline.lshtm.ac.uk/id/eprint/2264 Full text not available from this repository.

Dujardin, JC; Gonzalez-Pacanowska, D; Croft, SL; Olesen, OF; Spath, GF; (2010) Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas. Trends in parasitology, 26 (8). pp. 395-403. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2010.04.012 Full text not available from this repository.

Seifert, K; Escobar, P; Croft, SL; (2010) In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. The Journal of antimicrobial chemotherapy, 65 (3). pp. 508-11. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkp500 Full text not available from this repository.

Wube, AA; Bucar, F; Gibbons, S; Asres, K; Rattray, L; Croft, SL; (2010) Antiprotozoal Activity of Drimane and Coloratane Sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum In Vitro. Phytotherapy research, 24 (10). pp. 1468-1472. ISSN 0951-418X DOI: https://doi.org/10.1002/ptr.3126 Full text not available from this repository.

Yardley, V; Gamarro, F; Croft, SL; (2010) Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine. Antimicrobial agents and chemotherapy, 54 (12). pp. 5356-8. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00985-10 Full text not available from this repository.

2009

Dos Santos, DAP; Braga, PAD; da Silva, M; Fernandes, JB; Vieira, PC; Magalhaes, AF; Magalhaes, EG; Marsaioli, AJ; Moraes, VRD; Rattray, L; +1 more... Croft, SL; (2009) Anti-African trypanocidal and antimalarial activity of natural flavonoids, dibenzoylmethanes and synthetic analogues. The Journal of pharmacy and pharmacology, 61 (2). pp. 257-266. ISSN 0022-3573 DOI: https://doi.org/10.1211/jpp/61.02.0017 Full text not available from this repository.

Dos Santos, DAP; Vieira, PC; da Silva, M; Fernandes, JB; Rattray, L; Croft, SL; (2009) Antiparasitic Activities of Acridone Alkaloids from Swinglea glutinosa (Bl.) Merr. Journal of the Brazilian Chemical Society, 20 (4). pp. 644-651. ISSN 0103-5053 http://researchonline.lshtm.ac.uk/id/eprint/5126 Full text not available from this repository.

Gemma, S; Campiani, G; Butini, S; Joshi, BP; Kukreja, G; Coccone, SS; Bernetti, M; Persico, M; Nacci, V; Fiorini, I; +14 more... Novellino, E; Taramelli, D; Basilico, N; Parapini, S; Yardley, V; Croft, S; Keller-Maerki, S; Rottmann, M; Brun, R; Coletta, M; Marini, S; Guiso, G; Caccia, S; Fattorusso, C; (2009) Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials. Journal of medicinal chemistry, 52 (2). pp. 502-513. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm801352s Full text not available from this repository.

Guglielmo, S; Bertinaria, M; Rolando, B; Crosetti, M; Fruttero, R; Yardley, V; Croft, SL; Gasco, A; (2009) A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. European journal of medicinal chemistry, 44 (12). pp. 5071-5079. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2009.09.012 Full text not available from this repository.

Luna, KP; Hernandez, IP; Rueda, CM; Zorro, MM; Croft, SL; Escobar, P; (2009) In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica, 29 (3). pp. 448-455. ISSN 0120-4157 http://researchonline.lshtm.ac.uk/id/eprint/4496 Full text not available from this repository.

2008

Croft, SL; (2008) PKDL - a drug related phenomenon? The Indian journal of medical research, 128 (1). pp. 10-1. ISSN 0971-5916 http://researchonline.lshtm.ac.uk/id/eprint/6974
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Croft, SL; (2008) Kinetoplastida: new therapeutic strategies. Parasite (Paris, France), 15 (3). pp. 522-7. ISSN 1252-607X DOI: https://doi.org/10.1051/parasite/2008153522
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Fattorusso, C; Campiani, G; Kukreja, G; Persico, M; Butini, S; Romano, MP; Altarelli, M; Rost, S; Brindisi, M; Savini, L; +10 more... Novellino, E; Nacci, V; Fattorusso, E; Parapini, S; Basilico, N; Taramelli, D; Yardley, V; Croft, S; Borriello, M; Gemma, S; (2008) Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. Journal of medicinal chemistry, 51 (5). pp. 1333-1343. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm7012375 Full text not available from this repository.

Gemma, S; Campiani, G; Butini, S; Kukreja, G; Coccone, SS; Joshi, BP; Persico, M; Nacci, V; Fiorini, I; Novellino, E; +12 more... Fattorusso, E; Taglialatela-Scafati, O; Savini, L; Taramelli, D; Basilico, N; Parapini, S; Morace, G; Yardley, V; Croft, S; Coletta, M; Marini, S; Fattorusso, C; (2008) Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: Design, synthesis, and biological and structure-activity relationship studies. Journal of medicinal chemistry, 51 (5). pp. 1278-1294. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm701247k Full text not available from this repository.

Nanayakkara, NP; Ager, AL; Bartlett, MS; Yardley, V; Croft, SL; Khan, IA; McChesney, JD; Walker, LA; (2008) Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichloropheno xy]quinoline succinate. Antimicrobial agents and chemotherapy, 52 (6). pp. 2130-2137. ISSN 0066-4804 DOI: https://doi.org/10.1128/aac.00645-07 Full text not available from this repository.

Nanayakkara, NP; Ager, ALJr; Bartlett, MS; Yardley, V; Croft, SL; Khan, IA; McChesney, JD; Walker, LA; (2008) Antiparasitic Activity and Toxicity of Individual Enantiomers of the 8-Aminoquinoline, 8-[(4-Amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline Succinate. Antimicrobial agents and chemotherapy, 52 (6). pp. 2130-7. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00645-07 Full text not available from this repository.

Stuart, K; Brun, R; Croft, S; Fairlamb, A; Gürtler, RE; McKerrow, J; Reed, S; Tarleton, R; (2008) Kinetoplastids: related protozoan pathogens, different diseases. The Journal of clinical investigation, 118 (4). pp. 1301-1310. ISSN 0021-9738 DOI: https://doi.org/10.1172/JCI33945 Full text not available from this repository.

Wube, AA; Bucar, F; Gibbons, SZ; Asres, K; Rattray, L; Croft, SL; (2008) Antiprotozoal activity of sesquiterpenes from Warburgia ugandensis towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. Planta medica, 74 (9). p. 994. ISSN 0032-0943 http://researchonline.lshtm.ac.uk/id/eprint/7086 Full text not available from this repository.

2007

Blackie, MAL; Beagley, P; Croft, SL; Kendrick, H; Moss, JR; Chibale, K; (2007) Metallocene-based antimalarials: An exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. Bioorganic & medicinal chemistry, 15 (20). pp. 6510-6516. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2007.07.012 Full text not available from this repository.

Garnier, T; Mantyla, A; Jarvinen, T; Lawrence, J; Brown, M; Croft, S; (2007) In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs. The Journal of antimicrobial chemotherapy, 60 (4). pp. 802-10. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkm303 Full text not available from this repository.

Garnier, T; Mäntylä, A; Järvinen, T; Lawrence, MJ; Brown, MB; Croft, SL; (2007) Topical buparvaquone formulations for the treatment of cutaneous leishmaniasis. The Journal of pharmacy and pharmacology, 59 (1). pp. 41-9. ISSN 0022-3573 DOI: https://doi.org/10.1211/jpp.59.1.0006 Full text not available from this repository.

Haynes, RK; Wong, HN; Lee, KW; Lung, CM; Shek, LY; Williams, ID; Croft, SL; Vivas, L; Rattray, L; Stewart, L; +2 more... Wong, VK; Ko, BC; (2007) Preparation of N-Sulfonyl- and N-Carbonyl-11-Azaartemisinins with Greatly Enhanced Thermal Stabilities: in vitro Antimalarial Activities. ChemMedChem, 2 (10). pp. 1464-1479. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.200700065 Full text not available from this repository.

Rijal, S; Yardley, V; Chappuis, F; Decuypere, S; Khanal, B; Singh, R; Boelaert, M; de Doncker, S; Croft, S; Dujardin, JC; (2007) Antimonial treatment of visceral leishmaniasis: are current in vitro susceptibility assays adequate for prognosis of in vivo therapy outcome? Microbes and infection / Institut Pasteur, 9 (4). pp. 529-535. ISSN 1286-4579 DOI: https://doi.org/10.1016/j.micinf.2007.01.009 Full text not available from this repository.

Seifert, K; Lemke, A; Croft, SL; Kayser, O; (2007) Anti-leishmanial structure-activity-relationships of synthetic phospholipids: in vitro and in vivo activity of selected derivatives. Antimicrobial agents and chemotherapy, 51 (12). pp. 4525-8. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00465-07 Full text not available from this repository.

Seifert, K; Perez-Victoria, FJ; Stettler, M; Sánchez-Cañete, MP; Castanys, S; Gamarro, F; Croft, SL; (2007) Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. International journal of antimicrobial agents, 30 (3). pp. 229-35. ISSN 0924-8579 DOI: https://doi.org/10.1016/j.ijantimicag.2007.05.007 Full text not available from this repository.

Vivas, L; Rattray, L; Stewart, L; Bongard, E; Robinson, BL; Peters, W; Croft, SL; (2007) Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta tropica, 105 (3). pp. 222-8. ISSN 0001-706X DOI: https://doi.org/10.1016/j.actatropica.2007.12.005 Full text not available from this repository.

Vivas, L; Rattray, L; Stewart, LB; Robinson, BL; Fugmann, B; Haynes, RK; Peters, W; Croft, SL; (2007) Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. The Journal of antimicrobial chemotherapy, 59 (4). pp. 658-665. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkl563 Full text not available from this repository.

2006

Berman, J; Bryceson, ADM; Croft, S; Engel, J; Gutteridge, W; Karbwang, J; Sindermann, H; Soto, J; Sundar, S; Urbina, JA; (2006) Miltefosine: issues to be addressed in the future. Transactions of the Royal Society of Tropical Medicine and Hygiene, 100 Su. S41-4. ISSN 0035-9203 DOI: https://doi.org/10.1016/j.trstmh.2006.02.009 Full text not available from this repository.

Croft, SL; Seifert, K; Yardley, V; (2006) Current scenario of drug development for leishmaniasis. The Indian journal of medical research, 123 (3). pp. 399-410. ISSN 0971-5916 http://researchonline.lshtm.ac.uk/id/eprint/11722
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Croft, SL; Sundar, S; Fairlamb, AH; (2006) Drug resistance in leishmaniasis. Clinical microbiology reviews, 19 (1). 111-+. ISSN 0893-8512 DOI: https://doi.org/10.1128/CMR.19.1.111-126.2006 Full text not available from this repository.

Garnier, T; Brown, MB; Lawrence, MJ; Croft, SL; (2006) In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. The Journal of pharmacy and pharmacology, 58 (8). pp. 1043-54. ISSN 0022-3573 DOI: https://doi.org/10.1211/jpp.58.8.0004 Full text not available from this repository.

Gokhale, NH; Shirisha, K; Padhye, SB; Croft, SL; Kendrick, HD; McKee, V; (2006) Metalloantimalarials: Synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone. Bioorganic & medicinal chemistry letters, 16 (2). pp. 430-432. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2005.09.061 Full text not available from this repository.

Gros, L; Castillo-Acosta, VM; Jimenez Jimenez, C; Sealey-Cardona, M; Vargas, S; Manuel Estevez, A; Yardley, V; Rattray, L; Croft, SL; Ruiz-Perez, LM; +3 more... Urbina, JA; Gilbert, IH; Gonzalez-Pacanowska, D; (2006) New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. Antimicrobial agents and chemotherapy, 50 (8). pp. 2595-601. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01508-05 Full text not available from this repository.

Gros, L; Lorente, SO; Jimenez, CJ; Yardley, V; Rattray, L; Wharton, H; Little, S; Croft, SL; Ruiz-Perez, LM; Gonzalez-Pacanowska, D; +1 more... Gilbert, IH; (2006) Evaluation of Azasterols as Anti-Parasitics. Journal of medicinal chemistry, 49 (20). pp. 6094-6103. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm060290f Full text not available from this repository.

Haynes, RK; Fugmann, B; Stetter, J; Rieckmann, K; Heilmann, HD; Chan, HW; Cheung, MK; Lam, WL; Wong, HN; Croft, SL; +16 more... Vivas, L; Rattray, L; Stewart, L; Peters, W; Robinson, BL; Edstein, MD; Kotecka, B; Kyle, DE; Beckermann, B; Gerisch, M; Radtke, M; Schmuck, G; Steinke, W; Wollborn, U; Schmeer, K; Römer, A; (2006) Artemisone--a highly active antimalarial drug of the artemisinin class. Angewandte Chemie (International ed in English), 45 (13). pp. 2082-8. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.200503071 Full text not available from this repository.

Hudock, MP; Sanz-Rodriguez, CE; Song, YC; Chan, JMW; Zhang, YH; Odeh, S; Kosztowski, T; Leon-Rossell, A; Concepcion, JL; Yardley, V; +3 more... Croft, SL; Urbina, JA; Oldfield, E; (2006) Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. Journal of medicinal chemistry, 49 (1). pp. 215-223. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm0582625 Full text not available from this repository.

Laurent, T; Rijal, S; Yardley, V; Croft, S; De Doncker, S; Decuypere, S; Khanal, B; Singh, R; Schönian, G; Kuhls, K; +2 more... Chappuis, F; Dujardin, JC; (2006) Epidemiological dynamics of antimonial resistance in Leishmania donovani: Genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal. Infection, genetics and evolution, 7 (2). pp. 206-12. ISSN 1567-1348 DOI: https://doi.org/10.1016/j.meegid.2006.08.005 Full text not available from this repository.

Perez-Victoria, FJ; Sanchez-Canete, MP; Seifert, K; Croft, SL; Sundar, S; Castanys, S; Gamarro, F; (2006) Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. Drug resistance updates, 9 (1-2). pp. 26-39. ISSN 1368-7646 DOI: https://doi.org/10.1016/j.drup.2006.04.001 Full text not available from this repository.

Seifert, K; Croft, SL; (2006) In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. Antimicrobial agents and chemotherapy, 50 (1). pp. 73-9. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.50.1.73-79.2006 Full text not available from this repository.

Yardley, V; Ortuno, N; Llanos-Cuentas, A; Chappuis, F; Doncker, SD; Ramirez, L; Croft, S; Arevalo, J; Adaui, V; Bermudez, H; +2 more... Decuypere, S; Dujardin, JC; (2006) American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility? The Journal of infectious diseases, 194 (8). pp. 1168-75. ISSN 0022-1899 DOI: https://doi.org/10.1086/507710 Full text not available from this repository.

van Baren, C; Anao, I; Lira, PD; Debenedetti, S; Houghton, P; Croft, S; Martino, V; (2006) Triterpenic acids and flavonoids from Satureja parvifolia. Evaluation of their antiprotozoal activity. Zeitschrift fur Naturforschung C, Journal of biosciences, 61 (3-4). pp. 189-192. ISSN 0939-5075 http://researchonline.lshtm.ac.uk/id/eprint/11723 Full text not available from this repository.

2005

Conners, R; Schambach, F; Read, J; Cameron, A; Sessions, RB; Vivas, L; Easton, A; Croft, SL; Brady, RL; (2005) Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Molecular and biochemical parasitology, 142 (2). pp. 137-48. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2005.03.015 Full text not available from this repository.

Lorente, SO; Gomez, R; Jimenez, C; Cammerer, S; Yardley, V; de Luca-Fradley, K; Croft, SL; Perez, LMR; Urbina, J; Pacanowska, DG; +1 more... Gilbert, IH; (2005) Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. Bioorganic & medicinal chemistry, 13 (10). pp. 3519-3529. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2005.02.060 Full text not available from this repository.

Lorente, SO; Jimenez, CJ; Gros, L; Yardley, V; de Luca-Fradley, K; Croft, SL; Urbina, JA; Ruiz-Perez, LM; Pacanowska, DG; Gilbert, IH; (2005) Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasities. Bioorganic & medicinal chemistry, 13 (18). pp. 5435-5453. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2005.06.012 Full text not available from this repository.

Onyeibor, O; Croft, SL; Dodson, HI; Feiz-Haddad, M; Kendrick, H; Millington, NJ; Parapini, S; Phillips, RM; Seville, S; Shnyder, SD; +2 more... Taramelli, D; Wright, CW; (2005) Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. Journal of medicinal chemistry, 48 (7). pp. 2701-9. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm040893w Full text not available from this repository.

Vivas, L; Easton, A; Kendrick, H; Cameron, A; Lavandera, JL; Barros, D; de las Heras, FG; Brady, RL; Croft, SL; (2005) Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase. Experimental parasitology, 111 (2). pp. 105-14. ISSN 0014-4894 DOI: https://doi.org/10.1016/j.exppara.2005.06.007 Full text not available from this repository.

Wube, AA; Bucar, F; Asres, K; Gibbons, S; Rattray, L; Croft, SL; (2005) Antimalarial compounds from Kniphofia foliosa roots. Phytotherapy research, 19 (6). pp. 472-476. ISSN 0951-418X DOI: https://doi.org/10.1002/ptr.1635 Full text not available from this repository.

Yardley, V; Croft, SL; DE Doncker, S; Dujardin, JC; Koirala, S; Rijal, S; Miranda, C; Llanos-Cuentas, A; Chappuis, F; (2005) THE SENSITIVITY OF CLINICAL ISOLATES OF LEISHMANIA FROM PERU AND NEPAL TO MILTEFOSINE. The American journal of tropical medicine and hygiene, 73 (2). pp. 272-5. ISSN 0002-9637 http://researchonline.lshtm.ac.uk/id/eprint/13280
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2004

Anao, I; Houghton, P; Croft, S; (2004) Antiprotozoal activity guided fractionation of Sclerocarya birrea (A. Rich.) Hochst. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/6181 Full text not available from this repository.

Bailey, NJC; Wang, YL; Sampson, J; Davis, W; Whitcombe, I; Hylands, PJ; Croft, SL; Holmes, E; (2004) Prediction of anti-plasmodial activity of Artemisia annua extracts: application of H-1 NMR spectroscopy and chernometrics. Journal of pharmaceutical and biomedical analysis, 35 (1). p. 117. ISSN 0731-7085 DOI: https://doi.org/10.1016/j.jpba.2003.12.024 Full text not available from this repository.

Camacho, MD; Phillipson, JD; Croft, SL; Yardley, V; Solis, PN; (2004) In vitro antiprotozoal and cytotoxic activities of some alkaloids, quinones, flavonoids, and coumarins. Planta medica, 70 (1). pp. 70-72. ISSN 0032-0943 DOI: https://doi.org/10.1055/s-2004-815460 Full text not available from this repository.

Cameron, A; Read, J; Tranter, R; Winter, VJ; Sessions, RB; Brady, RL; Vivas, L; Easton, A; Kendrick, H; Croft, SL; +12 more... Barros, D; Lavandera, JL; Martin, JJ; Risco, F; Garcia-Ochoa, S; Gamo, FJ; Sanz, L; Leon, L; Ruiz, JR; Gabarro, R; Mallo, A; de Las Heras, FG; (2004) Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. The Journal of biological chemistry, 279 (30). p. 31429. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M402433200 Full text not available from this repository.

Carrico, D; Ohkanda, J; Kendrick, H; Yokoyama, K; Blaskovich, MA; Bucher, CJ; Buckner, FS; van Voorhis, WC; Chakrabarti, D; Croft, SL; +3 more... Gelb, MH; Sebti, SM; Hamilton, AD; (2004) In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. Bioorganic & medicinal chemistry. p. 6517. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.09.020 Full text not available from this repository.

Cottrell, DM; Capers, J; Salem, MM; Deluca-Fradley, K; Croft, SL; Werbovetz, KA; (2004) Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4- oxadiazoles. Bioorganic & medicinal chemistry, 12 (11). p. 2815. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.03.054 Full text not available from this repository.

Fidock, DA; Rosenthal, PJ; Croft, SL; Brun, R; Nwaka, S; (2004) Antimalarial drug discovery: Efficacy models for compound screening. Nature reviews Drug discovery, 3 (6). p. 509. ISSN 1474-1776 DOI: https://doi.org/10.1038/nrd1416 Full text not available from this repository.

Ghosh, S; Chan, JMW; Lea, CR; Meints, GA; Lewis, JC; Tovian, ZS; Flessner, RM; Loftus, TC; Bruchhaus, I; Kendrick, H; +5 more... Croft, SL; Kemp, RG; Kobayashi, S; Nozaki, T; Oldfield, E; (2004) Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. Journal of medicinal chemistry, 47 (1). pp. 175-187. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030084x Full text not available from this repository.

Grant, KM; Dunion, MH; Yardley, V; Skaltsounis, AL; Marko, D; Eisenbrand, G; Croft, SL; Meijer, L; Mottram, JC; (2004) Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: Chemical library screen and antileishmanial activity. Antimicrobial agents and chemotherapy, 48 (8). p. 3033. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.48.8.3033-3042.2004 Full text not available from this repository.

Haynes, RK; Ho, WY; Chan, HW; Fugmann, B; Stetter, J; Croft, SL; Vivas, L; Peters, W; Robinson, BL; (2004) Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity. Angewandte Chemie (International ed in English), 43 (11). pp. 1381-5. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.200352343 Full text not available from this repository.

Jung, M; Lee, K; Jung, H; Kendrick, H; Yardley, V; Croft, SL; (2004) Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives. Bioorganic & medicinal chemistry letters, 14 (8). p. 2001. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2003.12.104 Full text not available from this repository.

Liu, M; Wilairat, P; Croft, SL; Tan, ALC; Go, ML; (2004) Structure-activity relationships of antileishmanial and antimalarial chalcones (vol 11, pg 2729, 2003). Bioorganic & medicinal chemistry, 12 (6). p. 1569. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.01.023 Full text not available from this repository.

Lorente, SO; Rodrigues, JCF; Jimenez, CJ; Joyce-Menekse, M; Rodrigues, C; Croft, SL; Yardley, V; de Luca-Fradley, K; Ruiz-Perez, LM; Urbina, J; +3 more... de Souza, W; Pacanowska, DG; Gilbert, IH; (2004) Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. Antimicrobial agents and chemotherapy, 48 (8). p. 2937. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.48.8.2937-2950.2004 Full text not available from this repository.

Mantyla, A; Garnier, T; Rautio, R; Nevalainen, T; Vepsalainen, J; Koskinen, A; Croft, SL; Jarvinen, T; (2004) Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone. Journal of medicinal chemistry, 47 (1). pp. 188-195. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030868a Full text not available from this repository.

Mantyla, A; Rautio, J; Nevalainen, T; Vepsalainen, J; Juvonen, R; Kendrick, H; Garner, T; Croft, SL; Jarvinen, T; (2004) Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives. Bioorganic & medicinal chemistry, 12 (13). p. 3497. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.04.032 Full text not available from this repository.

Nan, A; Croft, SL; Yardley, V; Ghandehari, H; (2004) Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis. Journal of controlled release, 94 (1). pp. 115-127. ISSN 0168-3659 DOI: https://doi.org/10.1016/j.jconrel.2003.09.012 Full text not available from this repository.

Ohkanda, J; Buckner, FS; Lockman, JW; Yokoyama, K; Carrico, D; Eastman, R; de Luca-Fradley, K; Davies, W; Croft, SL; van Voorhis, WC; +3 more... Gelb, MH; Sebti, SM; Hamilton, AD; (2004) Design and Synthesis of Peptidomimetic Protein Farnesyltransferase Inhibitors as Anti-Trypanosoma brucei Agents. Journal of medicinal chemistry. pp. 432-445. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030236o Full text not available from this repository.

Saha, B; Tonkal, Amdj; Croft, S; Roy, S; (2004) Mast cells at the host-pathogen interface: host-protection versus immune evasion in leishmaniasis. Clinical and experimental immunology, 137 (1). p. 19. ISSN 0009-9104 DOI: https://doi.org/10.1111/j.1365-2249.2004.02505.x Full text not available from this repository.

Sindermann, H; Croft, SL; Engel, KR; Bommer, W; Eibl, HJ; Unger, C; Engel, J; (2004) Miltefosine (Impavido): the first oral treatment against leishmaniasis. Medical microbiology and immunology. p. 173. ISSN 0300-8584 DOI: https://doi.org/10.1007/s00430-003-0201-2 Full text not available from this repository.

de Castroa, SL; Santa-Ritaa, RM; Urbinab, JA; Croft, SL; (2004) Antiprotozoal Lysophospholipid Analogues: A Comparison of their Activity Against Trypanosomatid Parasites and Tumor Cells. Mini reviews in medicinal chemistry, 4 (2). pp. 141-51. ISSN 1389-5575 DOI: https://doi.org/10.2174/1389557043487439 Full text not available from this repository.

2003

Bal, G; van der Veken, P; Antonov, D; Lambeir, AM; Grellier, P; Croft, SL; Augustyns, K; Haemers, A; (2003) Prolylisoxazoles: Potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. Bioorganic & medicinal chemistry letters, 13 (17). pp. 2875-2878. ISSN 0960-894X DOI: https://doi.org/10.1016/s0960-894x(03)00579-1 Full text not available from this repository.

Camacho, MR; Phillipson, JD; Croft, SL; Solis, PN; Marshall, SJ; Ghazanfar, SA; (2003) Screening of plant extracts for antiprotozoal and cytotoxic activities. Journal of ethnopharmacology, 89 (2-3). pp. 185-191. ISSN 0378-8741 DOI: https://doi.org/10.1016/s0378-8741(03)00269-1 Full text not available from this repository.

Chauviere, G; Bouteille, B; Enanga, B; de Albuquerque, C; Croft, SL; Dumas, M; Perie, J; (2003) Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of medicinal chemistry, 46 (3). pp. 427-440. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm021030a Full text not available from this repository.

Chen, J; Kuznetsova, L; Chibale, K; Clarkson, C; Smith, P; Croft, SL; Ojima, I; (2003) Design, synthesis, and evaluation of taxanes as potential antimalarial agents. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/14865 Full text not available from this repository.

Croft, SL; (2003) Antiprotozoals. In: Finch, RG; Greenwood, D; Norrby, SR; Whitley, RJ, (eds.) Antibiotic and Chemotherapy. Churchill Livingstone, London, pp. 452-471. http://researchonline.lshtm.ac.uk/id/eprint/15630 Full text not available from this repository.

Croft, SL; Coombs, GH; (2003) Leishmaniasis- current chemotherapy and recent advances in the search for novel drugs. Trends in parasitology, 19 (11). pp. 502-8. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2003.09.008 Full text not available from this repository.

Croft, SL; Seifert, K; Duchene, M; (2003) Antiprotozoal activities of phospholipid analogues. Molecular and biochemical parasitology, 126 (2). pp. 165-72. ISSN 0166-6851 DOI: https://doi.org/10.1016/S0166-6851(02)00283-9 Full text not available from this repository.

Croft, SL; Vivas, L; Brooker, S; (2003) Recent advances in research and control of malaria, leishmaniasis, trypanosomiasis and schistosomiasis. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 9 (4). pp. 518-33. ISSN 1020-3397 http://researchonline.lshtm.ac.uk/id/eprint/13879 Full text not available from this repository.

Davies, CR; Kaye, P; Croft, SL; Sundar, S; (2003) Leishmaniasis: new approaches to disease control. BMJ (Clinical research ed), 326 (7385). pp. 377-82. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.326.7385.377
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Gokhale, NH; Padhye, SB; Billington, DC; Rathbone, DL; Croft, SL; Kendrick, HD; Anson, CE; Powell, AK; (2003) Synthesis and characterization of copper(II) complexes of pyridine-2-carboxamidrazones as potent antimalarial agents. Inorganica chimica acta, 349. pp. 23-29. ISSN 0020-1693 DOI: https://doi.org/10.1016/s0020-1693(03)00047-1 Full text not available from this repository.

Gokhale, NH; Padhye, SB; Croft, SL; Kendrick, HD; Davies, W; Anson, CE; Powell, AK; (2003) Transition metal complexes of buparvaquone as potent new antimalarial agents 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum. Journal of inorganic biochemistry, 95 (4). pp. 249-258. ISSN 0162-0134 DOI: https://doi.org/10.1016/s0162-0134(03)00134-x Full text not available from this repository.

Kayser, O; Kiderlen, AF; Croft, SL; (2003) Natural products as antiparasitic drugs. Parasitology research, 90. S55-S62. ISSN 0932-0113 DOI: https://doi.org/10.1007/s00436-002-0768-3 Full text not available from this repository.

Kayser, O; Kiderlen, AF; Croft, SL; (2003) Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae). Acta tropica, 86 (1). pp. 105-107. ISSN 0001-706X DOI: https://doi.org/10.1016/S0001-706X(02)00258-9 Full text not available from this repository.

Kayser, O; Olbrich, C; Croft, SL; Kiderlen, AF; (2003) Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs. Parasitology research, 90. S63-S70. ISSN 0932-0113 DOI: https://doi.org/10.1007/s00436-002-0769-2 Full text not available from this repository.

Kayser, O; Olbrich, C; Yardley, V; Kiderlen, AF; Croft, SL; (2003) Formulation of amphotericin B as nanosuspension for oral administration. International journal of pharmaceutics, 254 (1). pp. 73-75. ISSN 0378-5173 DOI: https://doi.org/10.1016/s0378-5173(02)00686-5 Full text not available from this repository.

Larabi, M; Yardley, V; Loiseau, PM; Appel, M; Legrand, P; Gulik, A; Bories, C; Croft, SL; Barratt, G; (2003) Toxicity and Antileishmanial Activity of a New Stable Lipid Suspension of Amphotericin B. Antimicrobial agents and chemotherapy, 47 (12). pp. 3774-3779. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.47.12.3774-3779.2003 Full text not available from this repository.

Liu, M; Wilairat, P; Croft, SL; Tan, AL; Go, ML; (2003) Structure-activity relationships of antileishmanial and antimalarial chalcones. Bioorganic & medicinal chemistry, 11 (13). pp. 2729-38. ISSN 0968-0896 DOI: https://doi.org/10.1016/s0968-0896(03)0233-5 Full text not available from this repository.

Magaraci, F; Jimenez, CJ; Rodrigues, C; Rodrigues, JCF; Braga, MV; Yardley, V; de Luca-Fradley, K; Croft, SL; de Souza, W; Ruiz-Perez, LM; +3 more... Urbina, J; Pacanowska, DG; Gilbert, IH; (2003) Azasterols as inhibitors of sterol 24-methyltransferase in leishmania species and Trypanosoma cruzi. Journal of medicinal chemistry, 46 (22). pp. 4714-4727. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm021114j Full text not available from this repository.

Pez, D; Leal, I; Zuccotto, F; Boussard, C; Brun, R; Croft, SL; Yardley, V; Perez, LMR; Pacanowska, DG; Gilbert, IH; (2003) 2,4-diaminopyrimidines as inhibitors of leishmanial and trypanosomal dihydrofolate reductase. Bioorganic & medicinal chemistry, 11 (22). pp. 4693-4711. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2003.08.012 Full text not available from this repository.

Ramirez, I; Carabot, A; Melendez, P; Carmona, J; Jimenez, M; Patel, AV; Crabb, TA; Blunden, G; Cary, PD; Croft, SL; +1 more... Costa, M; (2003) Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. Phytochemistry, 64 (2). pp. 645-647. ISSN 0031-9422 DOI: https://doi.org/10.1016/s0031-9422(03)00241-3 Full text not available from this repository.

Ren, HY; Grady, S; Banghart, M; Moulthrop, JS; Kendrick, H; Yardley, V; Croft, SL; Moyna, G; (2003) Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. European journal of medicinal chemistry, 38 (11-12). p. 949. ISSN 0223-5234 DOI: https://doi.org/10.1016/s0223-5234(03)00180-6 Full text not available from this repository.

Seifert, K; Matu, S; Javier Perez-Victoria, F; Castanys, S; Gamarro, F; Croft, SL; (2003) Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). International journal of antimicrobial agents, 22 (4). pp. 380-387. ISSN 0924-8579 DOI: https://doi.org/10.1016/s0924-8579(03)00125-0 Full text not available from this repository.

2002

Camacho, MD; Phillipson, JD; Croft, SL; Marley, D; Kirby, GC; Warhurst, DC; (2002) Assessment of the Antiprotozoal activity of Galphimia glauca, and the isolation of new nor-secofriedelanes and nor-friedelanes. Journal of natural products, 65 (10). pp. 1457-1461. ISSN 0163-3864 DOI: https://doi.org/10.1021/np010419i Full text not available from this repository.

Croft, SL; Yardley, V; (2002) Chemotherapy of leishmaniasis. Current pharmaceutical design, 8 (4). pp. 319-42. ISSN 1381-6128 DOI: https://doi.org/10.2174/1381612023396258 Full text not available from this repository.

Croft, SL; Yardley, V; Kendrick, H; (2002) Drug sensitivity of Leishmania species: some unresolved problems. Transactions of the Royal Society of Tropical Medicine and Hygiene, 96 Sup. S127-9. ISSN 0035-9203 http://researchonline.lshtm.ac.uk/id/eprint/16578 Full text not available from this repository.

Escobar, P; Matu, S; Marques, C; Croft, SL; (2002) Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. Acta tropica, 81 (2). pp. 151-7. ISSN 0001-706X DOI: https://doi.org/10.1016/S0001-706X(01)00197-8 Full text not available from this repository.

Gamier, T; Croft, SL; (2002) Topical treatment for cutaneous leishmaniasis. Current opinion in investigational drugs (London, England, 3 (4). pp. 538-44. ISSN 1472-4472 http://researchonline.lshtm.ac.uk/id/eprint/16580 Full text not available from this repository.

Guerin, PJ; Olliaro, P; Sundar, S; Boelaert, M; Croft, SL; Desjeux, P; Wasunna, MK; Bryceson, ADM; (2002) Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. The Lancet infectious diseases, 2 (8). pp. 494-501. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(02)00347-X Full text not available from this repository.

Hayhoe, S; McCrossan, M; Smith, A; Ellis, D; Croft, S; Mei, MF; (2002) Single-use acupuncture needles: scanning electron-microscopy of needle-tips. Acupuncture in medicine, 20 (1). pp. 11-8. ISSN 0964-5284 http://researchonline.lshtm.ac.uk/id/eprint/17861 Full text not available from this repository.

Jung, MK; Lee, K; Kendrick, H; Robinson, BL; Croft, SL; (2002) Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid. Journal of medicinal chemistry, 45 (22). pp. 4940-4. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm020244p Full text not available from this repository.

Kayser, O; Kiderlen, A; Croft, SL; (2002) Natural Products as potential antiparasitic drugs. In: Rahman, Atta-, Yr, (ed.) Studies in Natural Product Chemistry 26. Elsevier, pp. 779-848. http://researchonline.lshtm.ac.uk/id/eprint/15629 Full text not available from this repository.

Martin, MB; Sanders, JM; Kendrick, H; de Luca-Fradley, K; Lewis, JC; Grimley, JS; van Brussel, EM; Olsen, JR; Meints, GA; Burzynska, A; +3 more... Kafarski, P; Croft, SL; Oldfield, E; (2002) Activity of bisphosphonates against Trypanosoma brucei rhodesiense. Journal of medicinal chemistry, 45 (14). pp. 2904-14. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm0102809 Full text not available from this repository.

Muriithi, MW; Abraham, WR; Addae-Kyereme, J; Scowen, I; Croft, SL; Gitu, PM; Kendrick, H; Njagi, ENM; Wright, CW; (2002) Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: In vivo antimalarial activity and X- ray crystal structure of normelicopicine. Journal of natural products, 65 (7). pp. 956-9. ISSN 0163-3864 DOI: https://doi.org/10.1021/np0106182 Full text not available from this repository.

Yardley, V; Khan, AA; Martin, MB; Slifer, TR; Araujo, FG; Moreno, SN; Docampo, R; Croft, SL; Oldfield, E; (2002) In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrobial agents and chemotherapy, 46 (3). pp. 929-31. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.46.3.929-931.2002 Full text not available from this repository.

del Rayo Camacho, M; Phillipson, JD; Croft, SL; Marley, D; Kirby, GC; Warhurst, DC; (2002) Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. Journal of natural products, 65 (10). pp. 1457-61. ISSN 0163-3864 http://researchonline.lshtm.ac.uk/id/eprint/15748 Full text not available from this repository.

del Rayo Camacho, M; Phillipson, JD; Croft, SL; Rock, P; Marshall, SJ; Schiff, P. L., Jr; (2002) In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei. Phytotherapy research, 16 (5). pp. 432-6. ISSN 0951-418X DOI: https://doi.org/10.1002/ptr.929 Full text not available from this repository.

2001

Asres, K; Bucar, F; Knauder, E; Yardley, V; Kendrick, H; Croft, SL; (2001) In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. Phytotherapy research, 15 (7). pp. 613-7. ISSN 0951-418X http://researchonline.lshtm.ac.uk/id/eprint/16573 Full text not available from this repository.

Chibale, K; Haupt, H; Kendrick, H; Yardley, V; Saravanamuthu, A; Fairlamb, AH; Croft, SL; (2001) Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. Bioorganic & medicinal chemistry letters, 11 (19). pp. 2655-2657. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00528-5 Full text not available from this repository.

Croft, S; (2001) Antimalarial Chemotherapy: Mechanisms of Action, Resistance and New Directions in Drug Discovery. Drug discovery today, 6 (22). p. 1151. ISSN 1359-6446 http://researchonline.lshtm.ac.uk/id/eprint/16570 Full text not available from this repository.

Croft, SL; (2001) Monitoring drug resistance in leishmaniasis. Tropical medicine & international health, 6 (11). pp. 899-905. ISSN 1360-2276 http://researchonline.lshtm.ac.uk/id/eprint/16571 Full text not available from this repository.

Croft, SL; (2001) From natural products to drugs. Current opinion in infectious diseases, 14 (6). pp. 717-8. ISSN 0951-7375 http://researchonline.lshtm.ac.uk/id/eprint/16577 Full text not available from this repository.

Croft, SL; Sutherland, C; (2001) Antiprotozoan drugs. In: UNSPECIFIED, (ed.) Encyclopedia of Life Sciences. Nature Publishing Group, London, p. 10. http://researchonline.lshtm.ac.uk/id/eprint/17863 Full text not available from this repository.

Daunes, S; D'Silva, C; Kendrick, H; Yardley, V; Croft, SL; (2001) QSAR study on the contribution of log P and E-s to the in vitro antiprotozoal activity of glutathione derivatives. Journal of medicinal chemistry, 44 (18). pp. 2976-83. ISSN 0022-2623 http://researchonline.lshtm.ac.uk/id/eprint/16567 Full text not available from this repository.

Escobar, P; Yardley, V; Croft, SL; (2001) Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice. Antimicrobial agents and chemotherapy, 45 (6). pp. 1872-5. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.45.6.1872-1875.2001 Full text not available from this repository.

Luque-Ortega, JR; Rivero-Lezcano, OM; Croft, SL; Rivas, L; (2001) In vivo monitoring of intracellular ATP levels in Leishmania donovani promastigotes as a rapid method to screen drugs targeting bioenergetic metabolism. Antimicrobial agents and chemotherapy, 45 (4). pp. 1121-1125. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.45.4.1121-1125.2001 Full text not available from this repository.

Martin, MB; Grimley, JS; Lewis, JC; Heath, HT; Bailey, BN; Kendrick, H; Yardley, V; Caldera, A; Lira, R; Urbina, JA; +4 more... Moreno, SNJ; Docampo, R; Croft, SL; Oldfield, E; (2001) Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A potential route to chemotherapy. Journal of medicinal chemistry, 44 (6). pp. 909-16. ISSN 0022-2623 http://researchonline.lshtm.ac.uk/id/eprint/16563 Full text not available from this repository.

Murray, PJ; Kranz, M; Ladlow, M; Taylor, S; Berst, F; Holmes, AB; Keavey, KN; Jaxa-Chamiec, A; Seale, PW; Stead, P; +4 more... Upton, RJ; Croft, SL; Clegg, W; Elsegood, MRJ; (2001) The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. Bioorganic & medicinal chemistry letters, 11 (6). pp. 773-776. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00049-X Full text not available from this repository.

Nan, A; Nanayakkara, NPD; Walker, LA; Yardley, V; Croft, SL; Ghandehari, H; (2001) N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. Journal of controlled release, 77 (3). pp. 233-43. ISSN 0168-3659 http://researchonline.lshtm.ac.uk/id/eprint/16572 Full text not available from this repository.

Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; +1 more... Hamilton, AD; (2001) Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. Bioorganic & medicinal chemistry letters, 11 (6). pp. 761-764. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00055-5 Full text not available from this repository.

Oldfield, E; Martin, MB; Croft, SL; Rodriguez, N; Montalvetti, A; Bailey, BN; Docampo, R; Urbina, JA; Khan, AA; Slifer, TR; +2 more... Araujo, FG; Moreno, SNJ; (2001) Bisphosphonates as novel chemotherapeutic agents. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/16588 Full text not available from this repository.

Ren, HY; Grady, S; Gamenara, D; Heinzen, H; Moyna, P; Croft, SL; Kendrick, H; Yardley, V; Moyna, G; (2001) Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. Bioorganic & medicinal chemistry letters, 11 (14). pp. 1851-1854. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00308-0 Full text not available from this repository.

Salmon-Chemin, L; Buisine, E; Yardley, V; Kohler, S; Debreu, MA; Landry, V; Sergheraert, C; Croft, SL; Krauth-Siegel, RL; Davioud-Charvet, E; (2001) 2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity. Journal of medicinal chemistry, 44 (4). pp. 548-65. ISSN 0022-2623 http://researchonline.lshtm.ac.uk/id/eprint/16559 Full text not available from this repository.

Wright, CW; Addae-Kyereme, J; Breen, AG; Brown, JE; Cox, MF; Croft, SL; Gokcek, Y; Kendrick, H; Phillips, RM; Pollet, PL; (2001) Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. Journal of medicinal chemistry, 44 (19). pp. 3187-94. ISSN 0022-2623 http://researchonline.lshtm.ac.uk/id/eprint/16568 Full text not available from this repository.

del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN; (2001) Terpenoids from Guarea rhophalocarpa. Phytochemistry, 56 (2). pp. 203-10. ISSN 0031-9422 http://researchonline.lshtm.ac.uk/id/eprint/15746 Full text not available from this repository.

This list was generated on Thu Mar 21 10:08:34 2019 GMT.