Items where Author is "1209"

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Number of items: 160.

2018

O'Keeffe, A; (2018) Development of Novel Predictive 2D and 3D in Vitro Models For Anti-Leishmanial Drug Testing. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine.
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2017

Baker, DA; Stewart, LB; Large, JM; Bowyer, PW; Ansell, KH; Jiménez-Díaz, MB; El Bakkouri, M; Birchall, K; Dechering, KJ; Bouloc, NS; +19 more... (2017) A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. Nat Commun, 8 (1). p. 430. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-017-00572-x
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2016

Hendrickx, S; Guerin, PJ; Caljon, G; Croft, SL; Maes, L; (2016) Evaluating drug resistance in visceral leishmaniasis: the challenges. Parasitology. pp. 1-11. ISSN 0031-1820 DOI: https://doi.org/10.1017/S0031182016002031 Full text not available from this repository.

2015

Burrell-Saward, H; (2015) Development of an imaging model of a CNS infection with African trypanosomes. PhD thesis, London School of Hygiene & Tropical Medicine.
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Croft, SL; Ward, S; (2015) The Nobel Prize in Medicine 2015: Two drugs that changed global health. Science translational medicine, 7 (316). 316ed14. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aad5868 Full text not available from this repository.

Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C; (2015) Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. Gene therapy, 22 (8). pp. 628-35. ISSN 0969-7128 DOI: https://doi.org/10.1038/gt.2015.35
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2014

Das, S; Freier, A; Boussoffara, T; Das, S; Oswald, D; Losch, FO; Selka, M; Sacerdoti-Sierra, N; Schönian, G; Wiesmüller, KH; +10 more... (2014) Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. Science translational medicine, 6 (234). 234ra56. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.3008222 Full text not available from this repository.

Ganguly, NK; Croft, S; Singh, L; Sinha, S; Balganesh, T; (2014) Biomedicine and biotechnology: public health impact. BioMed research international, 2014. p. 524785. ISSN 2314-6133 DOI: https://doi.org/10.1155/2014/524785
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Lamour, SD; Veselkov, KA; Posma, JM; Giraud, E; Rogers, ME; Croft, S; Marchesi, JR; Holmes, E; Seifert, K; Saric, J; (2014) Metabolic, Immune, and Gut Microbial Signals Mount a Systems Response to Leishmania major Infection. Journal of proteome research, 14 (1). pp. 318-329. ISSN 1535-3893 DOI: https://doi.org/10.1021/pr5008202 Full text not available from this repository.

2013

Ahmed, A; Ginn, C; Croft, SL; Brocchini, S; (2013) Anti-infectives. In: Uchegbu, IF; Schätzlein, AG; Cheng, WP; Lalatsa, A, (eds.) Fundamentals of Pharmaceutical Nanoscience. Springer Science,, New York, pp. 429-464. ISBN 978-1-4614-9164-4 Full text not available from this repository.

Alvar, J; Croft, SL; Kaye, P; Khamesipour, A; Sundar, S; Reed, SG; (2013) Case study for a vaccine against leishmaniasis. Vaccine, 31. B244-B249. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2012.11.080 Full text not available from this repository.

Dellai, A; Appel, J; Bouraoui, A; Croft, S; Nefzi, A; (2013) Antimalarial and cytotoxic activities of chiral triamines. Bioorganic & medicinal chemistry letters, 23 (16). pp. 4579-4582. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2013.06.035 Full text not available from this repository.

Maes, L; Cos, P; Croft, SL; (2013) The relevance of susceptibility tests, breakpoints and markers. In: Pont-Sucre, A; Diaz, E; Padron-Nieves, M, (eds.) Drug resistance in Leishmania parasites. Springer-Verlag, Wien, pp. 407-429. Full text not available from this repository.

Mohamed-Ahmed, AHA; Les, KA; Seifert, K; Croft, SL; Brocchini, S; (2013) Noncovalent Connplexation of Amphotericin-B with Poly(alpha-glutamic acid). Molecular pharmaceutics, 10 (3). pp. 940-950. ISSN 1543-8384 DOI: https://doi.org/10.1021/mp300339p Full text not available from this repository.

2012

Croft, SL; Duparc, S; Arbe-Barnes, SJ; Craft, JC; Shin, CS; Fleckenstein, L; Borghini-Fuhrer, I; Rim, HJ; (2012) Review of pyronaridine anti-malarial properties and product characteristics. Malar J, 11. p. 270. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-11-270
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Mohamed-Ahmed, AH; Brocchini, S; Croft, SL; (2012) Recent advances in development of amphotericin B formulations for the treatment of visceral leishmaniasis. Current opinion in infectious diseases, 25 (6). pp. 695-702. ISSN 0951-7375 DOI: https://doi.org/10.1097/QCO.0b013e328359eff2 Full text not available from this repository.

Peña, S; Scarone, L; Manta, E; Stewart, L; Yardley, V; Croft, S; Serra, G; (2012) Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. Bioorganic & medicinal chemistry letters, 22 (15). pp. 4994-7. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.06.028 Full text not available from this repository.

2011

Baschong, W; Wittlin, S; Inglis, KA; Fairlamb, AH; Croft, SL; Kumar, TRS; Fidock, DA; Brun, R; (2011) Triclosan is minimally effective in rodent malaria models. Nature medicine, 17 (1). pp. 33-34. ISSN 1078-8956 DOI: https://doi.org/10.1038/nm0111-33 Full text not available from this repository.

Jeganathan, S; Sanderson, L; Dogruel, M; Rodgers, J; Croft, S; Thomas, SA; (2011) The Distribution of Nifurtimox Across the Healthy and Trypanosome-Infected Murine Blood-Brain and Blood-Cerebrospinal Fluid Barriers. The Journal of pharmacology and experimental therapeutics, 336 (2). pp. 506-515. ISSN 0022-3565 DOI: https://doi.org/10.1124/jpet.110.172981 Full text not available from this repository.

2010

Abazid, Nizar; (2010) Treatment of localised cutaneous Leishmania tropica infection in Aleppo, Syria and drug sensitivity of clinical isolates. PhD thesis, London School of Hygiene & Tropical Medicine.
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Croft, SL; Seifert, K; (2010) Antiprotozoal agents. In: Finch, RogerG; Greenwood, David; Whitley, RichardJ; Norrby, SRagnar, (eds.) Antibiotic and Chemotherapy: Expert Consult (9th Edition). Saunders. ISBN 0702040649 Full text not available from this repository.

Dujardin, JC; Gonzalez-Pacanowska, D; Croft, SL; Olesen, OF; Spath, GF; (2010) Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas. Trends in parasitology, 26 (8). pp. 395-403. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2010.04.012 Full text not available from this repository.

Wube, AA; Bucar, F; Gibbons, S; Asres, K; Rattray, L; Croft, SL; (2010) Antiprotozoal Activity of Drimane and Coloratane Sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum In Vitro. Phytotherapy research, 24 (10). pp. 1468-1472. ISSN 0951-418X DOI: https://doi.org/10.1002/ptr.3126 Full text not available from this repository.

2009

Dos Santos, DAP; Braga, PAD; da Silva, M; Fernandes, JB; Vieira, PC; Magalhaes, AF; Magalhaes, EG; Marsaioli, AJ; Moraes, VRD; Rattray, L; +1 more... (2009) Anti-African trypanocidal and antimalarial activity of natural flavonoids, dibenzoylmethanes and synthetic analogues. The Journal of pharmacy and pharmacology, 61 (2). pp. 257-266. ISSN 0022-3573 DOI: https://doi.org/10.1211/jpp/61.02.0017 Full text not available from this repository.

Dos Santos, DAP; Vieira, PC; da Silva, M; Fernandes, JB; Rattray, L; Croft, SL; (2009) Antiparasitic Activities of Acridone Alkaloids from Swinglea glutinosa (Bl.) Merr. Journal of the Brazilian Chemical Society, 20 (4). pp. 644-651. ISSN 0103-5053 Full text not available from this repository.

Gemma, S; Campiani, G; Butini, S; Joshi, BP; Kukreja, G; Coccone, SS; Bernetti, M; Persico, M; Nacci, V; Fiorini, I; +14 more... (2009) Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials. Journal of medicinal chemistry, 52 (2). pp. 502-513. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm801352s Full text not available from this repository.

Guglielmo, S; Bertinaria, M; Rolando, B; Crosetti, M; Fruttero, R; Yardley, V; Croft, SL; Gasco, A; (2009) A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. European journal of medicinal chemistry, 44 (12). pp. 5071-5079. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2009.09.012 Full text not available from this repository.

Luna, KP; Hernandez, IP; Rueda, CM; Zorro, MM; Croft, SL; Escobar, P; (2009) In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica, 29 (3). pp. 448-455. ISSN 0120-4157 Full text not available from this repository.

2008

Fattorusso, C; Campiani, G; Kukreja, G; Persico, M; Butini, S; Romano, MP; Altarelli, M; Rost, S; Brindisi, M; Savini, L; +10 more... (2008) Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. Journal of medicinal chemistry, 51 (5). pp. 1333-1343. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm7012375 Full text not available from this repository.

Gemma, S; Campiani, G; Butini, S; Kukreja, G; Coccone, SS; Joshi, BP; Persico, M; Nacci, V; Fiorini, I; Novellino, E; +12 more... (2008) Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: Design, synthesis, and biological and structure-activity relationship studies. Journal of medicinal chemistry, 51 (5). pp. 1278-1294. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm701247k Full text not available from this repository.

Stuart, K; Brun, R; Croft, S; Fairlamb, A; Gürtler, RE; McKerrow, J; Reed, S; Tarleton, R; (2008) Kinetoplastids: related protozoan pathogens, different diseases. The Journal of clinical investigation, 118 (4). pp. 1301-1310. ISSN 0021-9738 DOI: https://doi.org/10.1172/JCI33945 Full text not available from this repository.

Wube, AA; Bucar, F; Gibbons, SZ; Asres, K; Rattray, L; Croft, SL; (2008) Antiprotozoal activity of sesquiterpenes from Warburgia ugandensis towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. Planta medica, 74 (9). p. 994. ISSN 0032-0943 Full text not available from this repository.

2007

Garnier, T; Mantyla, A; Jarvinen, T; Lawrence, J; Brown, M; Croft, S; (2007) In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs. The Journal of antimicrobial chemotherapy, 60 (4). pp. 802-10. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkm303 Full text not available from this repository.

Garnier, T; Mäntylä, A; Järvinen, T; Lawrence, MJ; Brown, MB; Croft, SL; (2007) Topical buparvaquone formulations for the treatment of cutaneous leishmaniasis. The Journal of pharmacy and pharmacology, 59 (1). pp. 41-9. ISSN 0022-3573 DOI: https://doi.org/10.1211/jpp.59.1.0006 Full text not available from this repository.

Haynes, RK; Wong, HN; Lee, KW; Lung, CM; Shek, LY; Williams, ID; Croft, SL; Vivas, L; Rattray, L; Stewart, L; +2 more... (2007) Preparation of N-Sulfonyl- and N-Carbonyl-11-Azaartemisinins with Greatly Enhanced Thermal Stabilities: in vitro Antimalarial Activities. ChemMedChem, 2 (10). pp. 1464-1479. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.200700065 Full text not available from this repository.

Rijal, S; Yardley, V; Chappuis, F; Decuypere, S; Khanal, B; Singh, R; Boelaert, M; de Doncker, S; Croft, S; Dujardin, JC; (2007) Antimonial treatment of visceral leishmaniasis: are current in vitro susceptibility assays adequate for prognosis of in vivo therapy outcome? Microbes and infection / Institut Pasteur, 9 (4). pp. 529-535. ISSN 1286-4579 DOI: https://doi.org/10.1016/j.micinf.2007.01.009 Full text not available from this repository.

Vivas, L; Rattray, L; Stewart, L; Bongard, E; Robinson, BL; Peters, W; Croft, SL; (2007) Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta tropica, 105 (3). pp. 222-8. ISSN 0001-706X DOI: https://doi.org/10.1016/j.actatropica.2007.12.005 Full text not available from this repository.

Vivas, L; Rattray, L; Stewart, LB; Robinson, BL; Fugmann, B; Haynes, RK; Peters, W; Croft, SL; (2007) Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. The Journal of antimicrobial chemotherapy, 59 (4). pp. 658-665. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkl563 Full text not available from this repository.

2006

Berman, J; Bryceson, ADM; Croft, S; Engel, J; Gutteridge, W; Karbwang, J; Sindermann, H; Soto, J; Sundar, S; Urbina, JA; (2006) Miltefosine: issues to be addressed in the future. Transactions of the Royal Society of Tropical Medicine and Hygiene, 100 Suppl 1. S41-4. ISSN 0035-9203 DOI: https://doi.org/10.1016/j.trstmh.2006.02.009 Full text not available from this repository.

Croft, SL; Sundar, S; Fairlamb, AH; (2006) Drug resistance in leishmaniasis. Clinical microbiology reviews, 19 (1). 111-+. ISSN 0893-8512 DOI: https://doi.org/10.1128/CMR.19.1.111-126.2006 Full text not available from this repository.

Garnier, T; Brown, MB; Lawrence, MJ; Croft, SL; (2006) In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. The Journal of pharmacy and pharmacology, 58 (8). pp. 1043-54. ISSN 0022-3573 DOI: https://doi.org/10.1211/jpp.58.8.0004 Full text not available from this repository.

Gros, L; Castillo-Acosta, VM; Jimenez Jimenez, C; Sealey-Cardona, M; Vargas, S; Manuel Estevez, A; Yardley, V; Rattray, L; Croft, SL; Ruiz-Perez, LM; +3 more... (2006) New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. Antimicrobial agents and chemotherapy, 50 (8). pp. 2595-601. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01508-05 Full text not available from this repository.

Gros, L; Lorente, SO; Jimenez, CJ; Yardley, V; Rattray, L; Wharton, H; Little, S; Croft, SL; Ruiz-Perez, LM; Gonzalez-Pacanowska, D; +1 more... (2006) Evaluation of Azasterols as Anti-Parasitics. Journal of medicinal chemistry, 49 (20). pp. 6094-6103. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm060290f Full text not available from this repository.

Haynes, RK; Fugmann, B; Stetter, J; Rieckmann, K; Heilmann, HD; Chan, HW; Cheung, MK; Lam, WL; Wong, HN; Croft, SL; +16 more... (2006) Artemisone--a highly active antimalarial drug of the artemisinin class. Angewandte Chemie (International ed in English), 45 (13). pp. 2082-8. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.200503071 Full text not available from this repository.

Hudock, MP; Sanz-Rodriguez, CE; Song, YC; Chan, JMW; Zhang, YH; Odeh, S; Kosztowski, T; Leon-Rossell, A; Concepcion, JL; Yardley, V; +3 more... (2006) Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. Journal of medicinal chemistry, 49 (1). pp. 215-223. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm0582625 Full text not available from this repository.

Laurent, T; Rijal, S; Yardley, V; Croft, S; De Doncker, S; Decuypere, S; Khanal, B; Singh, R; Schönian, G; Kuhls, K; +2 more... (2006) Epidemiological dynamics of antimonial resistance in Leishmania donovani: Genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal. Infection, genetics and evolution, 7 (2). pp. 206-12. ISSN 1567-1348 DOI: https://doi.org/10.1016/j.meegid.2006.08.005 Full text not available from this repository.

Perez-Victoria, FJ; Sanchez-Canete, MP; Seifert, K; Croft, SL; Sundar, S; Castanys, S; Gamarro, F; (2006) Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. Drug resistance updates, 9 (1-2). pp. 26-39. ISSN 1368-7646 DOI: https://doi.org/10.1016/j.drup.2006.04.001 Full text not available from this repository.

Yardley, V; Ortuno, N; Llanos-Cuentas, A; Chappuis, F; Doncker, SD; Ramirez, L; Croft, S; Arevalo, J; Adaui, V; Bermudez, H; +2 more... (2006) American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility? The Journal of infectious diseases, 194 (8). pp. 1168-75. ISSN 0022-1899 DOI: https://doi.org/10.1086/507710 Full text not available from this repository.

van Baren, C; Anao, I; Lira, PD; Debenedetti, S; Houghton, P; Croft, S; Martino, V; (2006) Triterpenic acids and flavonoids from Satureja parvifolia. Evaluation of their antiprotozoal activity. Zeitschrift fur Naturforschung C, Journal of biosciences, 61 (3-4). pp. 189-192. ISSN 0939-5075 Full text not available from this repository.

2005

Conners, R; Schambach, F; Read, J; Cameron, A; Sessions, RB; Vivas, L; Easton, A; Croft, SL; Brady, RL; (2005) Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Molecular and biochemical parasitology, 142 (2). pp. 137-48. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2005.03.015 Full text not available from this repository.

Lorente, SO; Gomez, R; Jimenez, C; Cammerer, S; Yardley, V; de Luca-Fradley, K; Croft, SL; Perez, LMR; Urbina, J; Pacanowska, DG; +1 more... (2005) Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. Bioorganic & medicinal chemistry, 13 (10). pp. 3519-3529. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2005.02.060 Full text not available from this repository.

Lorente, SO; Jimenez, CJ; Gros, L; Yardley, V; de Luca-Fradley, K; Croft, SL; Urbina, JA; Ruiz-Perez, LM; Pacanowska, DG; Gilbert, IH; (2005) Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasities. Bioorganic & medicinal chemistry, 13 (18). pp. 5435-5453. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2005.06.012 Full text not available from this repository.

Onyeibor, O; Croft, SL; Dodson, HI; Feiz-Haddad, M; Kendrick, H; Millington, NJ; Parapini, S; Phillips, RM; Seville, S; Shnyder, SD; +2 more... (2005) Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. Journal of medicinal chemistry, 48 (7). pp. 2701-9. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm040893w Full text not available from this repository.

Vivas, L; Easton, A; Kendrick, H; Cameron, A; Lavandera, JL; Barros, D; de las Heras, FG; Brady, RL; Croft, SL; (2005) Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase. Experimental parasitology, 111 (2). pp. 105-14. ISSN 0014-4894 DOI: https://doi.org/10.1016/j.exppara.2005.06.007 Full text not available from this repository.

Wube, AA; Bucar, F; Asres, K; Gibbons, S; Rattray, L; Croft, SL; (2005) Antimalarial compounds from Kniphofia foliosa roots. Phytotherapy research, 19 (6). pp. 472-476. ISSN 0951-418X DOI: https://doi.org/10.1002/ptr.1635 Full text not available from this repository.

Yardley, V; Croft, SL; DE Doncker, S; Dujardin, JC; Koirala, S; Rijal, S; Miranda, C; Llanos-Cuentas, A; Chappuis, F; (2005) THE SENSITIVITY OF CLINICAL ISOLATES OF LEISHMANIA FROM PERU AND NEPAL TO MILTEFOSINE. The American journal of tropical medicine and hygiene, 73 (2). pp. 272-5. ISSN 0002-9637
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2004

Anao, I; Houghton, P; Croft, S; (2004) Antiprotozoal activity guided fractionation of Sclerocarya birrea (A. Rich.) Hochst. [Conference or Workshop Item] Full text not available from this repository.

Bailey, NJC; Wang, YL; Sampson, J; Davis, W; Whitcombe, I; Hylands, PJ; Croft, SL; Holmes, E; (2004) Prediction of anti-plasmodial activity of Artemisia annua extracts: application of H-1 NMR spectroscopy and chernometrics. Journal of pharmaceutical and biomedical analysis, 35 (1). p. 117. ISSN 0731-7085 DOI: https://doi.org/10.1016/j.jpba.2003.12.024 Full text not available from this repository.

Camacho, MD; Phillipson, JD; Croft, SL; Yardley, V; Solis, PN; (2004) In vitro antiprotozoal and cytotoxic activities of some alkaloids, quinones, flavonoids, and coumarins. Planta medica, 70 (1). pp. 70-72. ISSN 0032-0943 DOI: https://doi.org/10.1055/s-2004-815460 Full text not available from this repository.

Cameron, A; Read, J; Tranter, R; Winter, VJ; Sessions, RB; Brady, RL; Vivas, L; Easton, A; Kendrick, H; Croft, SL; +12 more... (2004) Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. The Journal of biological chemistry, 279 (30). p. 31429. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M402433200 Full text not available from this repository.

Carrico, D; Ohkanda, J; Kendrick, H; Yokoyama, K; Blaskovich, MA; Bucher, CJ; Buckner, FS; van Voorhis, WC; Chakrabarti, D; Croft, SL; +3 more... (2004) In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. Bioorganic & medicinal chemistry. p. 6517. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.09.020 Full text not available from this repository.

Cottrell, DM; Capers, J; Salem, MM; Deluca-Fradley, K; Croft, SL; Werbovetz, KA; (2004) Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4- oxadiazoles. Bioorganic & medicinal chemistry, 12 (11). p. 2815. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.03.054 Full text not available from this repository.

Fidock, DA; Rosenthal, PJ; Croft, SL; Brun, R; Nwaka, S; (2004) Antimalarial drug discovery: Efficacy models for compound screening. Nature reviews Drug discovery, 3 (6). p. 509. ISSN 1474-1776 DOI: https://doi.org/10.1038/nrd1416 Full text not available from this repository.

Ghosh, S; Chan, JMW; Lea, CR; Meints, GA; Lewis, JC; Tovian, ZS; Flessner, RM; Loftus, TC; Bruchhaus, I; Kendrick, H; +5 more... (2004) Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. Journal of medicinal chemistry, 47 (1). pp. 175-187. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030084x Full text not available from this repository.

Grant, KM; Dunion, MH; Yardley, V; Skaltsounis, AL; Marko, D; Eisenbrand, G; Croft, SL; Meijer, L; Mottram, JC; (2004) Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: Chemical library screen and antileishmanial activity. Antimicrobial agents and chemotherapy, 48 (8). p. 3033. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.48.8.3033-3042.2004 Full text not available from this repository.

Haynes, RK; Ho, WY; Chan, HW; Fugmann, B; Stetter, J; Croft, SL; Vivas, L; Peters, W; Robinson, BL; (2004) Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity. Angewandte Chemie (International ed in English), 43 (11). pp. 1381-5. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.200352343 Full text not available from this repository.

Liu, M; Wilairat, P; Croft, SL; Tan, ALC; Go, ML; (2004) Structure-activity relationships of antileishmanial and antimalarial chalcones (vol 11, pg 2729, 2003). Bioorganic & medicinal chemistry, 12 (6). p. 1569. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.01.023 Full text not available from this repository.

Lorente, SO; Rodrigues, JCF; Jimenez, CJ; Joyce-Menekse, M; Rodrigues, C; Croft, SL; Yardley, V; de Luca-Fradley, K; Ruiz-Perez, LM; Urbina, J; +3 more... (2004) Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. Antimicrobial agents and chemotherapy, 48 (8). p. 2937. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.48.8.2937-2950.2004 Full text not available from this repository.

Mantyla, A; Garnier, T; Rautio, R; Nevalainen, T; Vepsalainen, J; Koskinen, A; Croft, SL; Jarvinen, T; (2004) Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone. Journal of medicinal chemistry, 47 (1). pp. 188-195. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030868a Full text not available from this repository.

Mantyla, A; Rautio, J; Nevalainen, T; Vepsalainen, J; Juvonen, R; Kendrick, H; Garner, T; Croft, SL; Jarvinen, T; (2004) Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives. Bioorganic & medicinal chemistry, 12 (13). p. 3497. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2004.04.032 Full text not available from this repository.

Nan, A; Croft, SL; Yardley, V; Ghandehari, H; (2004) Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis. Journal of controlled release, 94 (1). pp. 115-127. ISSN 0168-3659 DOI: https://doi.org/10.1016/j.jconrel.2003.09.012 Full text not available from this repository.

Ohkanda, J; Buckner, FS; Lockman, JW; Yokoyama, K; Carrico, D; Eastman, R; de Luca-Fradley, K; Davies, W; Croft, SL; van Voorhis, WC; +3 more... (2004) Design and Synthesis of Peptidomimetic Protein Farnesyltransferase Inhibitors as Anti-Trypanosoma brucei Agents. Journal of medicinal chemistry. pp. 432-445. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030236o Full text not available from this repository.

Saha, B; Tonkal, Amdj; Croft, S; Roy, S; (2004) Mast cells at the host-pathogen interface: host-protection versus immune evasion in leishmaniasis. Clinical and experimental immunology, 137 (1). p. 19. ISSN 0009-9104 DOI: https://doi.org/10.1111/j.1365-2249.2004.02505.x Full text not available from this repository.

Sindermann, H; Croft, SL; Engel, KR; Bommer, W; Eibl, HJ; Unger, C; Engel, J; (2004) Miltefosine (Impavido): the first oral treatment against leishmaniasis. Medical microbiology and immunology. p. 173. ISSN 0300-8584 DOI: https://doi.org/10.1007/s00430-003-0201-2 Full text not available from this repository.

de Castroa, SL; Santa-Ritaa, RM; Urbinab, JA; Croft, SL; (2004) Antiprotozoal Lysophospholipid Analogues: A Comparison of their Activity Against Trypanosomatid Parasites and Tumor Cells. Mini reviews in medicinal chemistry, 4 (2). pp. 141-51. ISSN 1389-5575 DOI: https://doi.org/10.2174/1389557043487439 Full text not available from this repository.

2003

Bal, G; van der Veken, P; Antonov, D; Lambeir, AM; Grellier, P; Croft, SL; Augustyns, K; Haemers, A; (2003) Prolylisoxazoles: Potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. Bioorganic & medicinal chemistry letters, 13 (17). pp. 2875-2878. ISSN 0960-894X DOI: https://doi.org/10.1016/s0960-894x(03)00579-1 Full text not available from this repository.

Camacho, MR; Phillipson, JD; Croft, SL; Solis, PN; Marshall, SJ; Ghazanfar, SA; (2003) Screening of plant extracts for antiprotozoal and cytotoxic activities. Journal of ethnopharmacology, 89 (2-3). pp. 185-191. ISSN 0378-8741 DOI: https://doi.org/10.1016/s0378-8741(03)00269-1 Full text not available from this repository.

Chauviere, G; Bouteille, B; Enanga, B; de Albuquerque, C; Croft, SL; Dumas, M; Perie, J; (2003) Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of medicinal chemistry, 46 (3). pp. 427-440. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm021030a Full text not available from this repository.

Chen, J; Kuznetsova, L; Chibale, K; Clarkson, C; Smith, P; Croft, SL; Ojima, I; (2003) Design, synthesis, and evaluation of taxanes as potential antimalarial agents. [Conference or Workshop Item] Full text not available from this repository.

Croft, SL; (2003) Antiprotozoals. In: Finch, RG; Greenwood, D; Norrby, SR; Whitley, RJ, (eds.) Antibiotic and Chemotherapy. Churchill Livingstone, London, pp. 452-471. Full text not available from this repository.

Croft, SL; Coombs, GH; (2003) Leishmaniasis- current chemotherapy and recent advances in the search for novel drugs. Trends in parasitology, 19 (11). pp. 502-8. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2003.09.008 Full text not available from this repository.

Croft, SL; Seifert, K; Duchene, M; (2003) Antiprotozoal activities of phospholipid analogues. Molecular and biochemical parasitology, 126 (2). pp. 165-72. ISSN 0166-6851 DOI: https://doi.org/10.1016/S0166-6851(02)00283-9 Full text not available from this repository.

Gokhale, NH; Padhye, SB; Billington, DC; Rathbone, DL; Croft, SL; Kendrick, HD; Anson, CE; Powell, AK; (2003) Synthesis and characterization of copper(II) complexes of pyridine-2-carboxamidrazones as potent antimalarial agents. Inorganica chimica acta, 349. pp. 23-29. ISSN 0020-1693 DOI: https://doi.org/10.1016/s0020-1693(03)00047-1 Full text not available from this repository.

Kayser, O; Kiderlen, AF; Croft, SL; (2003) Natural products as antiparasitic drugs. Parasitology research, 90. S55-S62. ISSN 0932-0113 DOI: https://doi.org/10.1007/s00436-002-0768-3 Full text not available from this repository.

Kayser, O; Kiderlen, AF; Croft, SL; (2003) Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae). Acta tropica, 86 (1). pp. 105-107. ISSN 0001-706X DOI: https://doi.org/10.1016/S0001-706X(02)00258-9 Full text not available from this repository.

Kayser, O; Olbrich, C; Croft, SL; Kiderlen, AF; (2003) Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs. Parasitology research, 90. S63-S70. ISSN 0932-0113 DOI: https://doi.org/10.1007/s00436-002-0769-2 Full text not available from this repository.

Kayser, O; Olbrich, C; Yardley, V; Kiderlen, AF; Croft, SL; (2003) Formulation of amphotericin B as nanosuspension for oral administration. International journal of pharmaceutics, 254 (1). pp. 73-75. ISSN 0378-5173 DOI: https://doi.org/10.1016/s0378-5173(02)00686-5 Full text not available from this repository.

Larabi, M; Yardley, V; Loiseau, PM; Appel, M; Legrand, P; Gulik, A; Bories, C; Croft, SL; Barratt, G; (2003) Toxicity and Antileishmanial Activity of a New Stable Lipid Suspension of Amphotericin B. Antimicrobial agents and chemotherapy, 47 (12). pp. 3774-3779. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.47.12.3774-3779.2003 Full text not available from this repository.

Liu, M; Wilairat, P; Croft, SL; Tan, AL; Go, ML; (2003) Structure-activity relationships of antileishmanial and antimalarial chalcones. Bioorganic & medicinal chemistry, 11 (13). pp. 2729-38. ISSN 0968-0896 DOI: https://doi.org/10.1016/s0968-0896(03)0233-5 Full text not available from this repository.

Magaraci, F; Jimenez, CJ; Rodrigues, C; Rodrigues, JCF; Braga, MV; Yardley, V; de Luca-Fradley, K; Croft, SL; de Souza, W; Ruiz-Perez, LM; +3 more... (2003) Azasterols as inhibitors of sterol 24-methyltransferase in leishmania species and Trypanosoma cruzi. Journal of medicinal chemistry, 46 (22). pp. 4714-4727. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm021114j Full text not available from this repository.

Pez, D; Leal, I; Zuccotto, F; Boussard, C; Brun, R; Croft, SL; Yardley, V; Perez, LMR; Pacanowska, DG; Gilbert, IH; (2003) 2,4-diaminopyrimidines as inhibitors of leishmanial and trypanosomal dihydrofolate reductase. Bioorganic & medicinal chemistry, 11 (22). pp. 4693-4711. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2003.08.012 Full text not available from this repository.

Ramirez, I; Carabot, A; Melendez, P; Carmona, J; Jimenez, M; Patel, AV; Crabb, TA; Blunden, G; Cary, PD; Croft, SL; +1 more... (2003) Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. Phytochemistry, 64 (2). pp. 645-647. ISSN 0031-9422 DOI: https://doi.org/10.1016/s0031-9422(03)00241-3 Full text not available from this repository.

Ren, HY; Grady, S; Banghart, M; Moulthrop, JS; Kendrick, H; Yardley, V; Croft, SL; Moyna, G; (2003) Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. European journal of medicinal chemistry, 38 (11-12). p. 949. ISSN 0223-5234 DOI: https://doi.org/10.1016/s0223-5234(03)00180-6 Full text not available from this repository.

Seifert, K; Matu, S; Javier Perez-Victoria, F; Castanys, S; Gamarro, F; Croft, SL; (2003) Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). International journal of antimicrobial agents, 22 (4). pp. 380-387. ISSN 0924-8579 DOI: https://doi.org/10.1016/s0924-8579(03)00125-0 Full text not available from this repository.

2002

Camacho, MD; Phillipson, JD; Croft, SL; Marley, D; Kirby, GC; Warhurst, DC; (2002) Assessment of the Antiprotozoal activity of Galphimia glauca, and the isolation of new nor-secofriedelanes and nor-friedelanes. Journal of natural products, 65 (10). pp. 1457-1461. ISSN 0163-3864 DOI: https://doi.org/10.1021/np010419i Full text not available from this repository.

Croft, SL; Yardley, V; (2002) Chemotherapy of leishmaniasis. Current pharmaceutical design, 8 (4). pp. 319-42. ISSN 1381-6128 DOI: https://doi.org/10.2174/1381612023396258 Full text not available from this repository.

Escobar, P; Matu, S; Marques, C; Croft, SL; (2002) Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. Acta tropica, 81 (2). pp. 151-7. ISSN 0001-706X DOI: https://doi.org/10.1016/S0001-706X(01)00197-8 Full text not available from this repository.

Gamier, T; Croft, SL; (2002) Topical treatment for cutaneous leishmaniasis. Current opinion in investigational drugs (London, England, 3 (4). pp. 538-44. ISSN 1472-4472 Full text not available from this repository.

Guerin, PJ; Olliaro, P; Sundar, S; Boelaert, M; Croft, SL; Desjeux, P; Wasunna, MK; Bryceson, ADM; (2002) Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. The Lancet infectious diseases, 2 (8). pp. 494-501. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(02)00347-X Full text not available from this repository.

Hayhoe, S; McCrossan, M; Smith, A; Ellis, D; Croft, S; Mei, MF; (2002) Single-use acupuncture needles: scanning electron-microscopy of needle-tips. Acupuncture in medicine, 20 (1). pp. 11-8. ISSN 0964-5284 Full text not available from this repository.

Jung, MK; Lee, K; Kendrick, H; Robinson, BL; Croft, SL; (2002) Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid. Journal of medicinal chemistry, 45 (22). pp. 4940-4. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm020244p Full text not available from this repository.

Kayser, O; Kiderlen, A; Croft, SL; (2002) Natural Products as potential antiparasitic drugs. In: Rahman, Atta-, Yr, (ed.) Studies in Natural Product Chemistry 26. Elsevier, pp. 779-848. Full text not available from this repository.

Martin, MB; Sanders, JM; Kendrick, H; de Luca-Fradley, K; Lewis, JC; Grimley, JS; van Brussel, EM; Olsen, JR; Meints, GA; Burzynska, A; +3 more... (2002) Activity of bisphosphonates against Trypanosoma brucei rhodesiense. Journal of medicinal chemistry, 45 (14). pp. 2904-14. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm0102809 Full text not available from this repository.

Muriithi, MW; Abraham, WR; Addae-Kyereme, J; Scowen, I; Croft, SL; Gitu, PM; Kendrick, H; Njagi, ENM; Wright, CW; (2002) Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: In vivo antimalarial activity and X- ray crystal structure of normelicopicine. Journal of natural products, 65 (7). pp. 956-9. ISSN 0163-3864 DOI: https://doi.org/10.1021/np0106182 Full text not available from this repository.

Yardley, V; Khan, AA; Martin, MB; Slifer, TR; Araujo, FG; Moreno, SN; Docampo, R; Croft, SL; Oldfield, E; (2002) In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrobial agents and chemotherapy, 46 (3). pp. 929-31. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.46.3.929-931.2002 Full text not available from this repository.

del Rayo Camacho, M; Phillipson, JD; Croft, SL; Marley, D; Kirby, GC; Warhurst, DC; (2002) Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. Journal of natural products, 65 (10). pp. 1457-61. ISSN 0163-3864 Full text not available from this repository.

del Rayo Camacho, M; Phillipson, JD; Croft, SL; Rock, P; Marshall, SJ; Schiff, P. L., Jr; (2002) In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei. Phytotherapy research, 16 (5). pp. 432-6. ISSN 0951-418X DOI: https://doi.org/10.1002/ptr.929 Full text not available from this repository.

2001

Asres, K; Bucar, F; Knauder, E; Yardley, V; Kendrick, H; Croft, SL; (2001) In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. Phytotherapy research, 15 (7). pp. 613-7. ISSN 0951-418X Full text not available from this repository.

Chibale, K; Haupt, H; Kendrick, H; Yardley, V; Saravanamuthu, A; Fairlamb, AH; Croft, SL; (2001) Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. Bioorganic & medicinal chemistry letters, 11 (19). pp. 2655-2657. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00528-5 Full text not available from this repository.

Croft, S; (2001) Antimalarial Chemotherapy: Mechanisms of Action, Resistance and New Directions in Drug Discovery. Drug discovery today, 6 (22). p. 1151. ISSN 1359-6446 Full text not available from this repository.

Croft, SL; (2001) Monitoring drug resistance in leishmaniasis. Tropical medicine & international health, 6 (11). pp. 899-905. ISSN 1360-2276 Full text not available from this repository.

Croft, SL; (2001) From natural products to drugs. Current opinion in infectious diseases, 14 (6). pp. 717-8. ISSN 0951-7375 Full text not available from this repository.

Croft, SL; Sutherland, C; (2001) Antiprotozoan drugs. In: UNSPECIFIED, (ed.) Encyclopedia of Life Sciences. Nature Publishing Group, London, p. 10. Full text not available from this repository.

Daunes, S; D'Silva, C; Kendrick, H; Yardley, V; Croft, SL; (2001) QSAR study on the contribution of log P and E-s to the in vitro antiprotozoal activity of glutathione derivatives. Journal of medicinal chemistry, 44 (18). pp. 2976-83. ISSN 0022-2623 Full text not available from this repository.

Martin, MB; Grimley, JS; Lewis, JC; Heath, HT; Bailey, BN; Kendrick, H; Yardley, V; Caldera, A; Lira, R; Urbina, JA; +4 more... (2001) Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A potential route to chemotherapy. Journal of medicinal chemistry, 44 (6). pp. 909-16. ISSN 0022-2623 Full text not available from this repository.

Murray, PJ; Kranz, M; Ladlow, M; Taylor, S; Berst, F; Holmes, AB; Keavey, KN; Jaxa-Chamiec, A; Seale, PW; Stead, P; +4 more... (2001) The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. Bioorganic & medicinal chemistry letters, 11 (6). pp. 773-776. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00049-X Full text not available from this repository.

Nan, A; Nanayakkara, NPD; Walker, LA; Yardley, V; Croft, SL; Ghandehari, H; (2001) N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. Journal of controlled release, 77 (3). pp. 233-43. ISSN 0168-3659 Full text not available from this repository.

Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; +1 more... (2001) Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. Bioorganic & medicinal chemistry letters, 11 (6). pp. 761-764. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00055-5 Full text not available from this repository.

Oldfield, E; Martin, MB; Croft, SL; Rodriguez, N; Montalvetti, A; Bailey, BN; Docampo, R; Urbina, JA; Khan, AA; Slifer, TR; +2 more... (2001) Bisphosphonates as novel chemotherapeutic agents. [Conference or Workshop Item] Full text not available from this repository.

Ren, HY; Grady, S; Gamenara, D; Heinzen, H; Moyna, P; Croft, SL; Kendrick, H; Yardley, V; Moyna, G; (2001) Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. Bioorganic & medicinal chemistry letters, 11 (14). pp. 1851-1854. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00308-0 Full text not available from this repository.

Salmon-Chemin, L; Buisine, E; Yardley, V; Kohler, S; Debreu, MA; Landry, V; Sergheraert, C; Croft, SL; Krauth-Siegel, RL; Davioud-Charvet, E; (2001) 2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity. Journal of medicinal chemistry, 44 (4). pp. 548-65. ISSN 0022-2623 Full text not available from this repository.

Wright, CW; Addae-Kyereme, J; Breen, AG; Brown, JE; Cox, MF; Croft, SL; Gokcek, Y; Kendrick, H; Phillips, RM; Pollet, PL; (2001) Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. Journal of medicinal chemistry, 44 (19). pp. 3187-94. ISSN 0022-2623 Full text not available from this repository.

del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN; (2001) Terpenoids from Guarea rhophalocarpa. Phytochemistry, 56 (2). pp. 203-10. ISSN 0031-9422 Full text not available from this repository.

This list was generated on Wed Jul 18 03:37:13 2018 BST.