Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya.


Munywoki, PK; Ohuma, EO; Ngama, M; Bauni, E; Scott, JA; Nokes, DJ; (2013) Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya. Emerging infectious diseases, 19 (2). pp. 223-9. ISSN 1080-6040 DOI: 10.3201/eid1902.120940

[img]
Preview
Text - Published Version
License:

Download (478kB) | Preview

Abstract

Severe lower respiratory tract infection (LRTI) in infants caused by respiratory syncytial virus (RSV) has been associated with later pneumonia hospitalization among children. To determine risk for pneumonia after RSV hospitalization in infancy, we conducted a retrospective cohort analysis of 2,813 infants admitted to a hospital in Kenya and identified readmissions for pneumonia among this group during early childhood (<60 months of age). Incidence of readmission for pneumonia was higher for children whose first admission as infants was for LRTI and who were <3 months of age than for children who were first admitted as infants for non-LRTI, irrespective of RSV status. Incidence of readmission for pneumonia with wheeze was higher for children whose first admission involved RSV compared with those who had non-RSV LRTI. Excess pneumonia risk persisted for 2 years after the initial hospitalization. Close postdischarge follow-up of infants with LRTI, with or without RSV, could help prevent severe pneumonia later in childhood.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
PubMed ID: 23347702
Web of Science ID: 328172900006
URI: http://researchonline.lshtm.ac.uk/id/eprint/901100

Statistics


Download activity - last 12 months
Downloads since deposit
309Downloads
300Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item