Constituent country inequalities in myocardial infarction incidence and case fatality in men and women in the United Kingdom, 1996-2005


Davies, AR; Grundy, E; Nitsch, D; Smeeth, L; (2011) Constituent country inequalities in myocardial infarction incidence and case fatality in men and women in the United Kingdom, 1996-2005. Journal of public health (Oxford, England), 33 (1). pp. 131-138. ISSN 1741-3842 DOI: https://doi.org/10.1093/pubmed/fdq049

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Abstract

Understanding myocardial infarction (MI) incidence and case fatality trends across the four UK constituent countries is of importance following devolution of the government of health-care services. Retrospective cohort study using a primary care database (5.19 million patients) examining trends in incidence of first MI and 30-day case fatality. From 1996 to 2005, the incidence of MI decreased in all countries, but reductions were greater in England (men, -3.1%; women, -2.8%) and Wales (men, -3.3%; women, -4.6%) than in Scotland (men, -1.9%; women, -0.6%) and Northern Ireland (men no change, women, -0.8%) (average annual percentage change). Greater reductions in England and Wales than Scotland and Northern Ireland meant a widening of north-south difference in MI incidence over the study period. Downward trends in 30-day case fatality were found in each country but less regional variation was evident (England men, -12.0%, women, -11.0%; Wales men, -18.4%, women, -12.6%; Scotland men, -9.5%, women, -9.0%; Northern Ireland men, -8.6%, women, -13.0%). From 1996 to 2005, downward trends in the incidence of first MI and 30-day case fatality were evident in each constituent country. Greater improvements in case fatality, compared with incidence, were found within each country.

Item Type: Article
Keywords: case fatality, incidence, myocardial infarction, trends, United Kingdom, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, CORONARY-HEART-DISEASE, GENERAL-POPULATION, RISK, MORTALITY, TRENDS, RATES, VALIDATION, SURVIVAL, DATABASE
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Population Studies (1974-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 20634202
Web of Science ID: 287748800021
URI: http://researchonline.lshtm.ac.uk/id/eprint/891

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