Modelling the protective efficacy of alternative delivery schedules for intermittent preventive treatment of malaria in infants and children.


Cairns, M; Ghani, A; Okell, L; Gosling, R; Carneiro, I; Anto, F; Asoala, V; Owusu-Agyei, S; Greenwood, B; Chandramohan, D; Milligan, P; (2011) Modelling the protective efficacy of alternative delivery schedules for intermittent preventive treatment of malaria in infants and children. PLoS One, 6 (4). e18947. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0018947

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Abstract

Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is recommended by WHO where malaria incidence in infancy is high and SP resistance is low. The current delivery strategy is via routine Expanded Program on Immunisation contacts during infancy (EPI-IPTi). However, improvements to this approach may be possible where malaria transmission is seasonal, or where the malaria burden lies mainly outside infancy.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Distance Learning
Academic Services & Administration > Distance Learning

Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Malaria Centre
Centre for Maternal, Reproductive and Child Health (MARCH)
Tropical Epidemiology Group
PubMed ID: 21533088
Web of Science ID: 289719400036
URI: http://researchonline.lshtm.ac.uk/id/eprint/868

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