Mass antibiotic treatment and community protection in trachoma control programs.


Chidambaram, JD; Melese, M; Alemayehu, W; Yi, E; Prabriputaloong, T; Lee, DC; Cevallos, V; Zhou, Z; Whitcher, JP; Gaynor, BD; Lietman, TM; (2004) Mass antibiotic treatment and community protection in trachoma control programs. Clinical infectious diseases , 39 (9). e95-7. ISSN 1058-4838 DOI: 10.1086/424747

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Abstract

Azithromycin is highly effective against trachoma, but the practical difficulties of community-wide distribution often leave many individuals untreated. We demonstrate, after mass azithromycin treatment of a population in Ethiopia, an indirect protective effect that occurred among untreated children who resided in villages in which most individuals had been treated. Similarities with the indirect protection within a treated community (i.e., "herd protection") that has been observed in vaccination programs are discussed.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: Antimicrobial Resistance Centre (AMR)
PubMed ID: 15494901
Web of Science ID: 227491800031
URI: http://researchonline.lshtm.ac.uk/id/eprint/834630

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