Mass antibiotic treatment and community protection in trachoma control programs.
Chidambaram, JD; Melese, M; Alemayehu, W; Yi, E; Prabriputaloong, T; Lee, DC; Cevallos, V; Zhou, Z; Whitcher, JP; Gaynor, BD; Lietman, TM; (2004) Mass antibiotic treatment and community protection in trachoma control programs. Clinical infectious diseases , 39 (9). e95-7. ISSN 1058-4838 DOI: 10.1086/424747
Azithromycin is highly effective against trachoma, but the practical difficulties of community-wide distribution often leave many individuals untreated. We demonstrate, after mass azithromycin treatment of a population in Ethiopia, an indirect protective effect that occurred among untreated children who resided in villages in which most individuals had been treated. Similarities with the indirect protection within a treated community (i.e., "herd protection") that has been observed in vaccination programs are discussed.
|Faculty and Department:||Faculty of Infectious and Tropical Diseases > Dept of Clinical Research|
|Research Centre:||Antimicrobial Resistance Centre (AMR)|
|Web of Science ID:||227491800031|
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