Recent developments in blastocystis research.


Clark, CG; van der Giezen, M; Alfellani, MA; Stensvold, CR; (2013) Recent developments in blastocystis research. Advances in parasitology, 82. pp. 1-32. ISSN 0065-308X DOI: https://doi.org/10.1016/B978-0-12-407706-5.00001-0

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Abstract

Blastocystis is a common parasite of the human large intestine but has an uncertain role in disease. In this review, we appraise the published evidence addressing this and its weaknesses. Genetic diversity studies have led to the identification of numerous subtypes (STs) within the genus Blastocystis and, recently, methods for studying variation within STs have been developed, with implications for our understanding of host specificity. The geographic distribution of STs is summarised and the impact this may have on investigations into the role of the organism in disease is discussed. Finally, we describe the organelle and nuclear genome characteristics and look to future developments in the field.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases
Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
PubMed ID: 23548084
Web of Science ID: 321526300001
URI: http://researchonline.lshtm.ac.uk/id/eprint/748798

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