Sero-epidemiology of mumps in western Europe


Nardone, A; Pebody, RG; van Den Hof, S; Levy-Bruhl, D; Plesner, AM; Rota, MC; Tischer, A; Andrews, N; Berbers, G; Crovari, P; Edmunds, WJ; Gabutti, G; Saliou, P; Miller, E; (2003) Sero-epidemiology of mumps in western Europe. Epidemiology and infection, 131 (1). pp. 691-701. ISSN 0950-2688 DOI: 10.1017/S0950268803008768

[img]
Preview
Text - Published Version
License: Copyright the publishers

Download (2089Kb) | Preview

Abstract

Six countries (Denmark, England and Wales, France, Germany, Italy and The Netherlands) conducted large serological surveys for mumps, in the mid-1990s, as part of the European Sero-Epidemiology Network (ESEN). The assay results were standardized and related to the schedules and coverage of the immunization programmes and the reported incidence of mumps. Low incidence of disease and few susceptibles amongst adolescents and young adults was observed in countries with high mumps vaccine coverage (e.g. The Netherlands). High disease incidence and large proportions of mumps virus antibody negative samples in adolescent and young adult age groups was noted in countries with poor vaccine coverage (e.g. Italy). The build-up of susceptibles in older children and adolescents in England and Wales, France, the former West Germany and Italy indicate the possibility of further mumps outbreaks in secondary school environments. To control mumps in western Europe, current MMR immunization programmes will need to be strengthened in a number of countries. Sero-surveillance of mumps is an important component of disease control and its usefulness will be enhanced by the development of an international mumps standard.

Item Type: Article
Keywords: Adolescent, Adult, Age Factors, Aged, Antibodies, Viral/analysis, Child, Child, Preschool, Europe/epidemiology, Female, Health Policy, Health Surveys, Humans, Immunization Programs, Incidence, Infant, Infant, Newborn, Infection Control, Male, Measles-Mumps-Rubella Vaccine/administration & dosage/*immunology, Middle Aged, Mumps/*epidemiology/prevention & control, Seroepidemiologic Studies, Adolescent, Adult, Age Factors, Aged, Antibodies, Viral, analysis, Child, Child, Preschool, Europe, epidemiology, Female, Health Policy, Health Surveys, Humans, Immunization Programs, Incidence, Infant, Infant, Newborn, Infection Control, Male, Measles-Mumps-Rubella Vaccine, administration & dosage, immunology, Middle Aged, Mumps, epidemiology, prevention & control, Seroepidemiologic Studies
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Vaccine Centre
PubMed ID: 12948369
Web of Science ID: 185006100015
URI: http://researchonline.lshtm.ac.uk/id/eprint/6797

Statistics


Download activity - last 12 months
Downloads since deposit
280Downloads
501Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item