Making new vaccines affordable: a comparison of financing processes used to develop and deploy new meningococcal and pneumococcal conjugate vaccines.


Hargreaves, JR; Greenwood, B; Clift, C; Goel, A; Roemer-Mahler, A; Smith, R; Heymann, DL; (2011) Making new vaccines affordable: a comparison of financing processes used to develop and deploy new meningococcal and pneumococcal conjugate vaccines. Lancet, 378 (9806). pp. 1885-93. ISSN 0140-6736 DOI: 10.1016/S0140-6736(11)60687-9

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Abstract

: Mechanisms to increase access to health products are varied and controversial. Two innovative mechanisms have been used to accelerate the development of low-price supply lines for conjugate vaccines. The Meningitis Vaccine Project is a so-called push mechanism that facilitated technology transfer to an Indian company to establish capacity to manufacture a vaccine. The Advanced Market Commitment for pneumococcal vaccines is a so-called pull mechanism that guarantees companies a supplement paid in addition to the purchase price for vaccines for a specific period. We compare these approaches, identifying key dimensions of each and considering their potential for replication. We also discuss issues that the Global Alliance for Vaccines and Immunisation (GAVI) face now that these new vaccines are available. Progress towards GAVI's strategic aims is needed and funding is crucial. Approaches that decrease the financial pressure on GAVI and greatly increase political and financial engagement by low-income countries should also be considered.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Faculty of Public Health and Policy > Dept of Social and Environmental Health Research
Faculty of Public Health and Policy
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Public Health and Policy > Dept of Global Health and Development
Research Centre: Centre for Evaluation
Vaccine Centre
Tropical Epidemiology Group
Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 21664678
Web of Science ID: 297695800033
URI: http://researchonline.lshtm.ac.uk/id/eprint/620

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