Use of commercial enzyme immunoassays to detect antibodies to the herpes simplex virus type 2 glycoprotein G in a low-risk population in Hanoi, Vietnam.
Ngo, Thoai D;
Laeyendecker, Oliver;
La, Hanh;
Hogrefe, Wayne;
Morrow, Rhoda Ashley;
Quinn, Thomas C;
(2008)
Use of commercial enzyme immunoassays to detect antibodies to the herpes simplex virus type 2 glycoprotein G in a low-risk population in Hanoi, Vietnam.
Clinical and vaccine immunology, 15 (2).
pp. 382-384.
ISSN 1556-6811
DOI: https://doi.org/10.1128/CVI.00437-06
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Sera from 1,238 Vietnamese women in Hanoi were tested for herpes simplex virus type 2 (HSV-2). HSV-2 prevalence was 2.0%. The Kalon and Biokit assays showed significantly higher concordance to Western blotting data than did the Focus assay (P < 0.01). Screening by Focus and then retesting with Kalon/Biokit of positive samples can reduce falsely positive results significantly (P < 0.01).