Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes


MacDonald, MR; Petrie, MC; Home, PD; Romajda, M; Jones, NP; Beck-Nielsen, H; Gomis, R; Hanefeld, M; Pocock, SJ; Curtis, PS; McMurray, JJV; (2011) Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes. Diabetes care, 34 (6). pp. 1394-1396. ISSN 0149-5992 DOI: https://doi.org/10.2337/dc10-2398

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Abstract

OBJECTIVE-To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes. RESEARCH DESIGN AND METHODS-We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study. RESULTS-ECGs suitable for analysis were obtained from 669 participants. The prevalence of unrecognized Q-wave myocardial infarction at baseline was 1.9% (n = 13). The incidence of unrecognized Q-wave myocardial infarction at the end of 2 years of follow-up was 1.5/1,000-person-years (n = 2). One-third (13 of 39) of prevalent and one-quarter (2 of 8) of incident myocardial infarctions were unrecognized. CONCLUSIONS-Although the prevalence and incidence of myocardial infarction was low, unrecognized Q-wave myocardial infarctions made up a substantial proportion of all events.

Item Type: Article
Keywords: PROGNOSIS, REYKJAVIK
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Medical Statistics
PubMed ID: 21562320
Web of Science ID: 291846200029
URI: http://researchonline.lshtm.ac.uk/id/eprint/417

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