Mortality Reduction Associated with HIV/AIDS Care and Antiretroviral Treatment in Rural Malawi: Evidence from Registers, Coffin Sales and Funerals


Mwagomba, B; Zachariah, R; Massaquoi, M; Misindi, D; Manzi, M; Mandere, BC; Bemelmans, M; Philips, M; Kamoto, K; Schouten, EJ; Harries, AD; (2010) Mortality Reduction Associated with HIV/AIDS Care and Antiretroviral Treatment in Rural Malawi: Evidence from Registers, Coffin Sales and Funerals. PLoS One, 5 (5). ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0010452

[img]
Preview
Text - Published Version
License:

Download (170kB) | Preview

Abstract

Background: To report on the trend in all-cause mortality in a rural district of Malawi that has successfully scaled-up HIV/AIDS care including antiretroviral treatment (ART) to its population, through corroborative evidence from a) registered deaths at traditional authorities (TAs), b) coffin sales and c) church funerals. Methods and Findings: Retrospective study in 5 of 12 TAs (covering approximately 50% of the population) during the period 2000-2007. A total of 210 villages, 24 coffin workshops and 23 churches were included. There were a total of 18,473 registered deaths at TAs, 15781 coffins sold, and 2762 church funerals. Between 2000 and 2007, there was a highly significant linear downward trend in death rates, sale of coffins and church funerals (X-2 for linear trend: 338.4 P < 0.0001, 989 P < 0.0001 and 197, P < 0.0001 respectively). Using data from TAs as the most reliable source of data on deaths, overall death rate reduction was 37% (95% Cl:33-40) for the period. The mean annual incremental death rate reduction was 0.52/1000/year. Death rates decreased over time as the percentage of people living with HIV/AIDS enrolled into care and ART increased. Extrapolating these data to the entire district population, an estimated 10,156 (95% Cl: 9786-10259) deaths would have been averted during the 8-year period. Conclusions: Registered deaths at traditional authorities, the sale of coffins and church funerals showed a significant downward trend over a 8-year period which we believe was associated with the scaling up HIV/AIDS care and ART.

Item Type: Article
Keywords: hiv-1-infected patients, adult mortality, south-africa, addis-ababa, hiv, therapy, population, aids, ethiopia, district
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID: 20454611
Web of Science ID: 277305300004
URI: http://researchonline.lshtm.ac.uk/id/eprint/3711

Statistics


Download activity - last 12 months
Downloads since deposit
414Downloads
295Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item