This qualitative study sought to explore the experiences and perspectives of General Practitioners (GPs) in Barbados in relation to lesbian, gay, bisexual, and transgender (LGBT) patients, and to inform training in this area. Ten GPs were interviewed using a semi-structured guide and interviews audio-taped, transcribed verbatim, and analyzed thematically. Key themes were scant discussions on sexual health, practices, and identity; varied understandings of sexual and gender identity; and the invisible LGBT patient and their specific health care needs. Enhanced GP training is required to improve LGBT patient care, and will need to address societal, professional, and methodological challenges to implementation.