Effect of increased ART-CPT uptake on tuberculosis outcomes and associated factors, Burundi, 2009-2013.


Sawadogo, M; Ciza, F; Nzeyimana, SD; Shingiro, A; Ndikumana, T; Demeulenaere, T; Khogali, M; Edginton, M; Reid, AJ; Kumar, AM; Harries, AD; (2015) Effect of increased ART-CPT uptake on tuberculosis outcomes and associated factors, Burundi, 2009-2013. Public health action, 5 (4). pp. 214-6. ISSN 2220-8372 DOI: https://doi.org/10.5588/pha.15.0039

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Abstract

We retrospectively examined 3579 records of human immunodeficiency virus infected tuberculosis (TB) patients diagnosed from January 2009 to June 2013 in 55 TB treatment facilities in Burundi, to demonstrate whether improvement of combined cotrimoxazole preventive therapy and antiretroviral therapy (ART) uptake was accompanied by improvement of treatment outcomes, and to describe associated factors. Treatment success rates increased from 71% to 80% (P < 0.001). While loss to follow-up and transfer-out rates declined significantly, death rates decreased modestly, and remained high, at 14%. ART uptake was worse in suburban areas and private for-profit institutions. World Health Organization targets could be achieved if peripheral health facilities were prioritised. Abstract available from the publisher. Abstract available from the publisher.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID: 26767173
Web of Science ID: 375451900005
URI: http://researchonline.lshtm.ac.uk/id/eprint/2551677

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