Abstracting knowledge from the protein data bank.


Furnham, N; Laskowski, RA; Thornton, JM; (2013) Abstracting knowledge from the protein data bank. Biopolymers, 99 (3). pp. 183-8. ISSN 0006-3525 DOI: https://doi.org/10.1002/bip.22107

Full text not available from this repository. (Request a copy)

Abstract

: In the 40 years since its inception, the Protein Data Bank (PDB) has amassed over 80,000 experimentally determined structural models of proteins, plus many models of DNA and RNA fragments. The majority of the protein models have contributed, in some way, to an understanding of their particular protein's function, be it through the conformation of its catalytic residues, the details of its interactions with other proteins, substrate molecules, DNA, and so on. However, the totality of the data in the PDB provides a rich source of more generalized knowledge about proteins, their molecular biology, and evolution. Here, we describe how the focus of protein structural analysis has developed over the past 40 years. © 2012 Wiley Periodicals, Inc. Biopolymers 99: 183-188, 2013.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
PubMed ID: 23023892
Web of Science ID: 313833300003
URI: http://researchonline.lshtm.ac.uk/id/eprint/2374029

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
141Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item