2015 Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.


Dejaco, C; Singh, YP; Perel, P; Hutchings, A; Camellino, D; Mackie, S; Abril, A; Bachta, A; Balint, P; Barraclough, K; Bianconi, L; Buttgereit, F; Carsons, S; Ching, D; Cid, M; Cimmino, M; Diamantopoulos, A; Docken, W; Duftner, C; Fashanu, B; Gilbert, K; Hildreth, P; Hollywood, J; Jayne, D; Lima, M; Maharaj, A; Mallen, C; Martinez-Taboada, V; Maz, M; Merry, S; Miller, J; Mori, S; Neill, L; Nordborg, E; Nott, J; Padbury, H; Pease, C; Salvarani, C; Schirmer, M; Schmidt, W; Spiera, R; Tronnier, D; Wagner, A; Whitlock, M; Matteson, EL; Dasgupta, B; (2015) 2015 Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. Annals of the rheumatic diseases, 74 (10). pp. 1799-807. ISSN 0003-4967 DOI: https://doi.org/10.1136/annrheumdis-2015-207492

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Abstract

Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

Item Type: Article
Faculty and Department: Faculty of Public Health and Policy > Dept of Health Services Research and Policy
Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Nutrition and Public Health Interventions Research (2003-2012)
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 26359488
Web of Science ID: 361043200006
URI: http://researchonline.lshtm.ac.uk/id/eprint/2299132

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