Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae.


Bossé, JT; Li, Y; Atherton, TG; Walker, S; Williamson, SM; Rogers, J; Chaudhuri, RR; Weinert, LA; Holden, MT; Maskell, DJ; Tucker, AW; Wren, BW; Rycroft, AN; Langford, PR; (2015) Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae. Veterinary microbiology, 178 (3-4). pp. 279-82. ISSN 0378-1135 DOI: 10.1016/j.vetmic.2015.05.020

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Abstract

: The complete nucleotide sequence of a 7.7kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
Research Centre: Antimicrobial Resistance Centre (AMR)
PubMed ID: 26049592
Web of Science ID: 356979300015
URI: http://researchonline.lshtm.ac.uk/id/eprint/2210791

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