Evidence-based vector control? Improving the quality of vector control trials.


Wilson, AL; Boelaert, M; Kleinschmidt, I; Pinder, M; Scott, TW; Tusting, LS; Lindsay, SW; (2015) Evidence-based vector control? Improving the quality of vector control trials. Trends in parasitology, 31 (8). pp. 380-90. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2015.04.015

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Abstract

: Vector-borne diseases (VBDs) such as malaria, dengue, and leishmaniasis cause a high level of morbidity and mortality. Although vector control tools can play a major role in controlling and eliminating these diseases, in many cases the evidence base for assessing the efficacy of vector control interventions is limited or not available. Studies assessing the efficacy of vector control interventions are often poorly conducted, which limits the return on investment of research funding. Here we outline the principal design features of Phase III vector control field studies, highlight major failings and strengths of published studies, and provide guidance on improving the design and conduct of vector control studies. We hope that this critical assessment will increase the impetus for more carefully considered and rigorous design of vector control studies.<br/>

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Malaria Centre
Tropical Epidemiology Group
PubMed ID: 25999026
Web of Science ID: 359876700010
URI: http://researchonline.lshtm.ac.uk/id/eprint/2173668

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