Leishmania (Viannia) spp. dissemination and tissue tropism in naturally infected dogs (Canis familiaris)


Reithinger, R; Lambson, BE; Barker, DC; Counihan, H; Espinoza, CJ; Gonzalez, JS; Davies, CR; (2002) Leishmania (Viannia) spp. dissemination and tissue tropism in naturally infected dogs (Canis familiaris). Transactions of the Royal Society of Tropical Medicine and Hygiene, 96 (1). pp. 76-8. ISSN 0035-9203 DOI: 10.1016/S0035-9203(02)90249-X

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Abstract

First evidence is presented for Leishmania (Viannia) spp. dissemination and tissue tropism in the domestic dog. Using PCR and histology, parasites were detected in the conjunctiva, lung, lymph nodes and ovaries of 2 naturally infected Peruvian dogs. The detection of parasites in the blood indicates that parasite dissemination to those organs may have been haematogenous.

Item Type: Article
Keywords: Animal, Dog Diseases/*parasitology, Dogs, Female, Fibrosis/parasitology/veterinary, Leishmaniasis, Cutaneous/parasitology/*veterinary, Liver/parasitology, Lymph Nodes/parasitology, Ovary/parasitology, Parasitemia/diagnosis/veterinary, Polymerase Chain Reaction/methods/veterinary, Spleen/parasitology, Support, Non-U.S. Gov't, Animal, Dog Diseases, parasitology, Dogs, Female, Fibrosis, parasitology, veterinary, Leishmaniasis, Cutaneous, parasitology, veterinary, Liver, parasitology, Lymph Nodes, parasitology, Ovary, parasitology, Parasitemia, diagnosis, veterinary, Polymerase Chain Reaction, methods, veterinary, Spleen, parasitology, Support, Non-U.S. Gov't
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection
Research Centre: Leishmaniasis Group
PubMed ID: 11926001
Web of Science ID: 174546600017
URI: http://researchonline.lshtm.ac.uk/id/eprint/16686

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