Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?


Ranson, H; N'guessan, R; Lines, J; Moiroux, N; Nkuni, Z; Corbel, V; (2011) Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control? Trends in parasitology, 27 (2). pp. 91-8. ISSN 1471-4922 DOI: 10.1016/j.pt.2010.08.004

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Abstract

The use of pyrethroid insecticides in malaria vector control has increased dramatically in the past decade through the scale up of insecticide treated net distribution programmes and indoor residual spraying campaigns. Inevitably, the major malaria vectors have developed resistance to these insecticides and the resistance alleles are spreading at an exceptionally rapid rate throughout Africa. Although substantial progress has been made on understanding the causes of pyrethroid resistance, remarkably few studies have focused on the epidemiological impact of resistance on current malaria control activities. As we move into the malaria eradication era, it is vital that the implications of insecticide resistance are understood and strategies to mitigate these effects are implemented.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Antimicrobial Resistance Centre (AMR)
Malaria Centre
PubMed ID: 20843745
Web of Science ID: 287632000009
URI: http://researchonline.lshtm.ac.uk/id/eprint/1625

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