The National Liver Transplantation audit: an overview of patients presenting for liver transplantation from 1994 to 1998. On behalf of the Steering Group of the UK Liver Transplantation Audit


Hartley, P; Petruckevitch, A; Reeves, B; Rolles, K; (2001) The National Liver Transplantation audit: an overview of patients presenting for liver transplantation from 1994 to 1998. On behalf of the Steering Group of the UK Liver Transplantation Audit. The British journal of surgery, 88 (1). pp. 52-8. ISSN 0007-1323 DOI: https://doi.org/10.1046/j.1365-2168.2001.01609.x

Full text not available from this repository.

Abstract

BACKGROUND: The aim of this study was to describe current clinical practice in liver transplantation in the UK and Ireland, to provide overall 1-year graft and patient survival rates, and to study some preoperative risk factors. METHODS: All patients receiving a liver transplant in the UK or Ireland between 1 March 1994 and 30 September 1998 were included. Data were collected on patients at the time of transplantation, 3 months after grafting and annually thereafter until the patient's death. The main outcome measures were graft and patient survival at 1 year. RESULTS: A total of 3102 liver transplants were carried out, of which 87 per cent were first transplants. The mean age at first transplantation was 42 (range 0-76) years. The most common indications for transplantation were primary biliary cirrhosis, alcoholic cirrhosis and posthepatitis C cirrhosis, but variations existed between sexes and centres. Risk factors associated with lower graft and patient survival were the presence of acute disease, being transplanted from hospital, and the need for renal and/or ventilatory support before operation. CONCLUSION: Donor and recipient demographics are consistent with data held by the European Liver Transplant Registry, as are 1-year graft and patient survival rates. Variation across centres in factors such as the primary indication for liver transplantation, population demographics, the clinical status of each patient, incidence of retransplantation and other risk factors contributes to the problem of adjusting for case mix.

Item Type: Article
Keywords: Adolescent, Adult, Age Distribution, Aged, Cause of Death, Child, Child, Preschool, Graft Survival, Great Britain/epidemiology, Human, Infant, Infant, Newborn, Ireland/epidemiology, Liver Diseases/epidemiology/surgery, Liver Transplantation/mortality/*statistics & numerical data, Medical Audit, Middle Aged, Prognosis, Risk Factors, Sex Distribution, Support, Non-U.S. Gov't, Survival Analysis, Adolescent, Adult, Age Distribution, Aged, Cause of Death, Child, Child, Preschool, Graft Survival, Great Britain, epidemiology, Human, Infant, Infant, Newborn, Ireland, epidemiology, Liver Diseases, epidemiology, surgery, Liver Transplantation, mortality, statistics & numerical data, Medical Audit, Middle Aged, Prognosis, Risk Factors, Sex Distribution, Support, Non-U.S. Gov't, Survival Analysis
Faculty and Department: Faculty of Public Health and Policy > Dept of Health Services Research and Policy
PubMed ID: 11136310
Web of Science ID: 166522600008
URI: http://researchonline.lshtm.ac.uk/id/eprint/15474

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
331Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item