Case report: Schistosoma mansoni infection: failure of standard treatment with praziquantel in a returned traveller


Lawn, SD; Lucas, SB; Chiodini, PL; (2003) Case report: Schistosoma mansoni infection: failure of standard treatment with praziquantel in a returned traveller. Transactions of the Royal Society of Tropical Medicine and Hygiene, 97 (1). pp. 100-1. ISSN 0035-9203 DOI: 10.1016/S0035-9203(03)90038-1

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Abstract

Heavy reliance upon praziquantel for the treatment of schistosomiasis raises concerns over potential development of drug resistance. We describe a British traveller who acquired Schistosoma mansoni infection in East Africa and in whom repeated standard 40 mg/kg doses of praziquantel failed to clear the infection despite no opportunity for reinfection.

Item Type: Article
Keywords: Adult, Anthelmintics/*therapeutic use, Case Report, Drug Resistance, Human, Male, Praziquantel/*therapeutic use, Schistosomiasis mansoni/*drug therapy, Travel, Treatment Outcome, Adult, Anthelmintics, therapeutic use, Drug Resistance, Human, Male, Praziquantel, therapeutic use, Schistosomiasis mansoni, drug therapy, Travel, Treatment Outcome
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID: 12886814
Web of Science ID: 184231000026
URI: http://researchonline.lshtm.ac.uk/id/eprint/15041

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