Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health Study


Lawlor, DA; Smith, GD; Ebrahim, S; (2004) Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health Study. American journal of public health, 94 (8). pp. 1386-92. ISSN 0090-0036 DOI: https://doi.org/10.2105/AJPH.94.8.1386

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Abstract

OBJECTIVES: We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women. METHODS: We conducted a cross-sectional analysis of 3444 women aged 60 to 79 years. RESULTS: There was an independent linear association between childhood and adult SES and coronary heart disease. The association between childhood SES and coronary heart disease was attenuated when we adjusted for insulin resistance syndrome, adult smoking, physical activity, biomarkers of childhood nutrition, and passive smoking. CONCLUSIONS: The association between adverse childhood SES and coronary heart disease is in part mediated through insulin resistance, which may be influenced by poor childhood nutrition, and in part through the association between childhood SES and adult behavioral risk factors.

Item Type: Article
Keywords: Aged, Child, Child Nutrition, Child Welfare/*statistics & numerical data, Coronary Disease/epidemiology/*etiology, Cross-Sectional Studies, Exercise, Female, Great Britain/epidemiology, Health Behavior, Health Surveys, Humans, Life Style, Metabolic Syndrome X/epidemiology/etiology, Middle Aged, *Postmenopause, Poverty/*statistics & numerical data, Prevalence, Questionnaires, Research Support, Non-U.S. Gov't, Risk Factors, Smoking/adverse effects/epidemiology, *Social Class, Socioeconomic Factors, Urban Health/statistics & numerical data, Women's Health, Aged, Child, Child Nutrition, Child Welfare, statistics & numerical data, Coronary Disease, epidemiology, etiology, Cross-Sectional Studies, Exercise, Female, Great Britain, epidemiology, Health Behavior, Health Surveys, Humans, Life Style, Metabolic Syndrome X, epidemiology, etiology, Middle Aged, Postmenopause, Poverty, statistics & numerical data, Prevalence, Questionnaires, Research Support, Non-U.S. Gov't, Risk Factors, Smoking, adverse effects, epidemiology, Social Class, Socioeconomic Factors, Urban Health, statistics & numerical data, Women's Health
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 15284048
Web of Science ID: 223047600031
URI: http://researchonline.lshtm.ac.uk/id/eprint/12736

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