Intermittent Preventive Treatment of Malaria Provides Substantial Protection against Malaria in Children Already Protected by an Insecticide-Treated Bednet in Mali: A Randomised, Double-Blind, Placebo-Controlled Trial.


Dicko, A; Diallo, AI; Tembine, I; Dicko, Y; Dara, N; Sidibe, Y; Santara, G; Diawara, H; Conaré, T; Djimde, A; Chandramohan, D; Cousens, S; Milligan, PJ; Diallo, DA; Doumbo, OK; Greenwood, B; (2011) Intermittent Preventive Treatment of Malaria Provides Substantial Protection against Malaria in Children Already Protected by an Insecticide-Treated Bednet in Mali: A Randomised, Double-Blind, Placebo-Controlled Trial. PLoS medicine, 8 (2). e1000407. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1000407

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Abstract

Previous studies have shown that in areas of seasonal malaria transmission, intermittent preventive treatment of malaria in children (IPTc), targeting the transmission season, reduces the incidence of clinical malaria. However, these studies were conducted in communities with low coverage with insecticide-treated nets (ITNs). Whether IPTc provides additional protection to children sleeping under an ITN has not been established.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Malaria Centre
Centre for Maternal, Reproductive and Child Health (MARCH)
Tropical Epidemiology Group
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PubMed ID: 21304923
Web of Science ID: 287657600002
URI: http://researchonline.lshtm.ac.uk/id/eprint/1263

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