Ultrasonic locating devices for central venous cannulation: meta-analysis


Hind, D; Calvert, N; McWilliams, R; Davidson, A; Paisley, S; Beverley, C; Thomas, S; (2003) Ultrasonic locating devices for central venous cannulation: meta-analysis. BMJ, 327 (7411). p. 361. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.327.7411.361

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Abstract

OBJECTIVES: To assess the evidence for the clinical effectiveness of ultrasound guided central venous cannulation. DATA SOURCES: 15 electronic bibliographic databases, covering biomedical, science, social science, health economics, and grey literature. DESIGN: Systematic review and meta-analysis of randomised controlled trials. Populations Patients scheduled for central venous access. INTERVENTION REVIEWED: Guidance using real time two dimensional ultrasonography or Doppler needles and probes compared with the anatomical landmark method of cannulation. DATA EXTRACTION: Risk of failed catheter placement (primary outcome), risk of complications from placement, risk of failure on first attempt at placement, number of attempts to successful catheterisation, and time (seconds) to successful catheterisation. DATA SYNTHESIS: 18 trials (1646 participants) were identified. Compared with the landmark method, real time two dimensional ultrasound guidance for cannulating the internal jugular vein in adults was associated with a significantly lower failure rate both overall (relative risk 0.14, 95% confidence interval 0.06 to 0.33) and on the first attempt (0.59, 0.39 to 0.88). Limited evidence favoured two dimensional ultrasound guidance for subclavian vein and femoral vein procedures in adults (0.14, 0.04 to 0.57 and 0.29, 0.07 to 1.21, respectively). Three studies in infants confirmed a higher success rate with two dimensional ultrasonography for internal jugular procedures (0.15, 0.03 to 0.64). Doppler guided cannulation of the internal jugular vein in adults was more successful than the landmark method (0.39, 0.17 to 0.92), but the landmark method was more successful for subclavian vein procedures (1.48, 1.03 to 2.14). No significant difference was found between these techniques for cannulation of the internal jugular vein in infants. An indirect comparison of relative risks suggested that two dimensional ultrasonography would be more successful than Doppler guidance for subclavian vein procedures in adults (0.09, 0.02 to 0.38). CONCLUSIONS: Evidence supports the use of two dimensional ultrasonography for central venous cannulation.

Item Type: Article
Keywords: Adult, Catheterization, Central Venous/adverse effects/*methods, Femoral Vein, Humans, Infant, Jugular Veins, Randomized Controlled Trials, Risk Factors, Subclavian Vein, Ultrasonography, Doppler, Ultrasonography, Interventional/*methods, Adult, Catheterization, Central Venous, adverse effects, methods, Femoral Vein, Humans, Infant, Jugular Veins, Randomized Controlled Trials, Risk Factors, Subclavian Vein, Ultrasonography, Doppler, Ultrasonography, Interventional, methods
Faculty and Department: Faculty of Public Health and Policy > Dept of Health Services Research and Policy
PubMed ID: 12919984
Web of Science ID: 184864200014
URI: http://researchonline.lshtm.ac.uk/id/eprint/10374

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