Increased risk for malaria in chronically malnourished children under 5 years of age in rural Gambia


Deen, JL; Walraven, GE; von Seidlein, L; (2002) Increased risk for malaria in chronically malnourished children under 5 years of age in rural Gambia. Journal of tropical pediatrics, 48 (2). pp. 78-83. ISSN 0142-6338 DOI: 10.1093/tropej/48.2.78

Full text not available from this repository.

Abstract

Malaria and malnutrition cause high morbidity and mortality in rural sub-Saharan Africa. To explore the relationship between nutritional status and malaria, a cohort of Gambian children under 5 years of age was followed weekly during one malaria season. Anthropometric measurements were made at the beginning and at the end of the season. A total of 55/107 (51.4 per cent) children with baseline stunting, defined as having a height-for-age z-score below -2 standard deviations, subsequently experienced malaria episodes, compared to 145/380 (38.2 per cent) children who were not stunted (RR = 1.35; 95 per cent CI, 1.08-1.69; p value = 0.01). Neither wasting (weight-for-height z-score below -2 standard deviations) nor undernutrition (weight-for-age z-score below -2 standard deviations) influenced susceptibility to malaria. Adjustment for characteristics of age, sex, and ethnicity did not significantly change the risk ratios. Malaria had no effect on the nutritional status from the beginning to the end of the malaria season. Our findings suggest that chronically malnourished children may be at higher risk for developing malaria episodes.

Item Type: Article
Keywords: Animals, Body Height, Body Weight, Child, Preschool, Chronic Disease, Disease Susceptibility, Female, Gambia/epidemiology, Humans, Infant, Malaria, Falciparum/*complications/epidemiology/mortality, Male, Nutrition Disorders/*complications/epidemiology/mortality, Prospective Studies, Rural Population, Animals, Body Height, Body Weight, Child, Preschool, Chronic Disease, Disease Susceptibility, Female, Gambia, epidemiology, Humans, Infant, Malaria, Falciparum, complications, epidemiology, mortality, Male, Nutrition Disorders, complications, epidemiology, mortality, Prospective Studies, Rural Population
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
PubMed ID: 12022433
Web of Science ID: 175163200004
URI: http://researchonline.lshtm.ac.uk/id/eprint/10244

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
305Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item