Prevention of increasing rates of treatment failure by combining sulfadoxine-pyrimethamine with artesunate or amodiaquine for the sequential treatment of malaria

Dorsey, G; Vlahos, J; Kamya, MR; Staedke, SG; Rosenthal, PJ; (2003) Prevention of increasing rates of treatment failure by combining sulfadoxine-pyrimethamine with artesunate or amodiaquine for the sequential treatment of malaria. The Journal of infectious diseases, 188 (8). pp. 1231-8. ISSN 0022-1899 DOI: https://doi.org/10.1086/378523

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https://doi.org/10.1086/378523

Abstract

Item Type Article
Keywords Amodiaquine/administration & dosage/pharmacology/*therapeutic use, Animals, Antimalarials/administration & dosage/pharmacology/*therapeutic use, Artemisinins/administration & dosage/pharmacology/*therapeutic use, Child, Preschool, Dihydropteroate Synthase/genetics, Drug Administration Schedule, Drug Combinations, *Drug Resistance/genetics, Drug Therapy, Combination, Humans, Infant, Malaria, Falciparum/*drug therapy/parasitology, Mutation, Plasmodium falciparum/drug effects, Pyrimethamine/administration & dosage/pharmacology/*therapeutic use, Sesquiterpenes/administration & dosage/pharmacology/*therapeutic use, Sulfadoxine/administration & dosage/pharmacology/*therapeutic use, Tetrahydrofolate Dehydrogenase/genetics, Treatment Failure, Treatment Outcome, Amodiaquine, administration & dosage, pharmacology, therapeutic use, Animals, Antimalarials, administration & dosage, pharmacology, therapeutic use, Artemisinins, administration & dosage, pharmacology, therapeutic use, Child, Preschool, Dihydropteroate Synthase, genetics, Drug Administration Schedule, Drug Combinations, Drug Resistance, genetics, Drug Therapy, Combination, Humans, Infant, Malaria, Falciparum, drug therapy, parasitology, Mutation, Plasmodium falciparum, drug effects, Pyrimethamine, administration & dosage, pharmacology, therapeutic use, Sesquiterpenes, administration & dosage, pharmacology, therapeutic use, Sulfadoxine, administration & dosage, pharmacology, therapeutic use, Tetrahydrofolate Dehydrogenase, genetics, Treatment Failure, Treatment Outcome
Faculty and Department Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre Malaria Centre
PubMed ID 14551894
ISI 185850100019

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