Year Authors/Creators Item Type Full Text

Article

Quantitative Analyses Reveal Novel Roles for N-Glycosylation in a Major Enteric Bacterial Pathogen. (2019) Abouelhadid, Sherif; North, Simon J; Hitchen, Paul; Vohra, Prerna; Chintoan-Uta, Cosmin; Stevens, Mark; Dell, Anne; Cuccui, Jon; Wren, Brendan W

Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance. (2020) Abouelhadid, Sherif; Raynes, John; Bui, Tam; Cuccui, Jon; Wren, Brendan W

HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread. (2025) Baiyegunhi, Omolara O; Mthembu, Kensane; Reuschl, Ann-Kathrin; Ojwach, Doty; Farinre, Omotayo; Maimela, Murunwa; Balinda, Sheila; Price, Matt; Bunders, Madeleine J; Altfeld, Marcus; Jolly, Clare; Mann, Jaclyn; Ndung’u, Thumbi

Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery. (2017) Bald, Dirk; Villellas, Cristina; Lu, Ping; Koul, Anil

EspZ of enteropathogenic and enterohemorrhagic Escherichia coli regulates type III secretion system protein translocation. (2012) Berger, Cedric N; Crepin, Valerie F; Baruch, Kobi; Mousnier, Aurelie; Rosenshine, Ilan; Frankel, Gad

Mucosal Immune Profiles Associated with Diarrheal Disease Severity in Shigella- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study. (2022) Buskirk, Amanda D; Ndungo, Esther; Shimanovich, Avital A; Lam, Diana; Blackwelder, William C; Ikumapayi, Usman N; Ma, Bing; Powell, Helen; Antonio, Martin; Nataro, James P; Kaper, James B; Pasetti, Marcela F picture_as_pdf

Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy. (2016) Bustinduy, Amaya L; Waterhouse, David; de Sousa-Figueiredo, Jose C; Roberts, Stephen A; Atuhaire, Aaron; Van Dam, Govert J; Corstjens, Paul LAM; Scott, Janet T; Stanton, Michelle C; Kabatereine, Narcis B; Ward, Stephen; Hope, William W; Stothard, J Russell

What's in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B. (2016) Connor, Thomas R; Owen, Sian V; Langridge, Gemma; Connell, Steve; Nair, Satheesh; Reuter, Sandra; Dallman, Timothy J; Corander, Jukka; Tabing, Kristine C; Le Hello, Simon; Fookes, Maria; Doublet, Benoît; Zhou, Zhemin; Feltwell, Theresa; Ellington, Matthew J; Herrera, Silvia; Gilmour, Matthew; Cloeckaert, Axel; Achtman, Mark; Parkhill, Julian; Wain, John; De Pinna, Elizabeth; Weill, François-Xavier; Peters, Tansy; Thomson, Nick

Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples. (2017) Cowell, Annie N; Loy, Dorothy E; Sundararaman, Sesh A; Valdivia, Hugo; Fisch, Kathleen; Lescano, Andres G; Baldeviano, G Christian; Durand, Salomon; Gerbasi, Vince; Sutherland, Colin J; Nolder, Debbie; Vinetz, Joseph M; Hahn, Beatrice H; Winzeler, Elizabeth A

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection. (2016) Cuypers, Bart; Lecordier, Laurence; Meehan, Conor J; Van den Broeck, Frederik; Imamura, Hideo; Büscher, Philippe; Dujardin, Jean-Claude; Laukens, Kris; Schnaufer, Achim; Dewar, Caroline; Lewis, Michael; Balmer, Oliver; Azurago, Thomas; Kyei-Faried, Sardick; Ohene, Sally-Ann; Duah, Boateng; Homiah, Prince; Mensah, Ebenezer Kofi; Anleah, Francis; Franco, Jose Ramon; Pays, Etienne; Deborggraeve, Stijn

High Levels of Recombination among Streptococcus pneumoniae Isolates from the Gambia. (2011) Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP

High levels of recombination among Streptococcus pneumoniae isolates from the Gambia. (2011) Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP

Sleeping Beauty and the Story of the Bacille Calmette-Guérin Vaccine. (2016) Fletcher, Helen A

Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites. (2023) Fréville, Aline; Ressurreição, Margarida; van Ooij, Christiaan

Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria. (2022) Gibson, Amanda J; Stiens, Jennifer; Passmore, Ian J; Faulkner, Valwynne; Miculob, Josephous; Willcocks, Sam; Coad, Michael; Berg, Stefan; Werling, Dirk; Wren, Brendan W; Nobeli, Irene; Villarreal-Ramos, Bernardo; Kendall, Sharon L

Genomic Surveillance of Enterococcus faecium Reveals Limited Sharing of Strains and Resistance Genes between Livestock and Humans in the United Kingdom. (2018) Gouliouris, Theodore; Raven, Kathy E; Ludden, Catherine; Blane, Beth; Corander, Jukka; Horner, Carolyne S; Hernandez-Garcia, Juan; Wood, Paul; Hadjirin, Nazreen F; Radakovic, Milorad; Holmes, Mark A; de Goffau, Marcus; Brown, Nicholas M; Parkhill, Julian; Peacock, Sharon J

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. (2020) Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. (2020) Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J

Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection. (2015) Hochman, Sarah E; Madaline, Theresa F; Wassmer, Samuel C; Mbale, Emmie; Choi, Namjong; Seydel, Karl B; Whitten, Richard O; Varughese, Julie; Grau, Georges ER; Kamiza, Steve; Molyneux, Malcolm E; Taylor, Terrie E; Lee, Sunhee; Milner, Danny A; Kim, Kami

Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes. (2022) Hocking, Suzanne E; Stewart, Lindsay B; Freville, Aline; Reid, Adam J; Tarr, Sarah J; Tetteh, Kevin KA; Flueck, Christian; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Diakite, Mahamadou; Awandare, Gordon A; Conway, David J

Transient Silencing of Antibiotic Resistance by Mutation Represents a Significant Potential Source of Unanticipated Therapeutic Failure. (2019) Kime, Louise; Randall, Christopher P; Banda, Frank I; Coll, Francesc; Wright, John; Richardson, Joseph; Empel, Joanna; Parkhill, Julian; O'Neill, Alex J

Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins. (2018) Klemm, Elizabeth J; Shakoor, Sadia; Page, Andrew J; Qamar, Farah Naz; Judge, Kim; Saeed, Dania K; Wong, Vanessa K; Dallman, Timothy J; Nair, Satheesh; Baker, Stephen; Shaheen, Ghazala; Qureshi, Shahida; Yousafzai, Mohammad Tahir; Saleem, Muhammad Khalid; Hasan, Zahra; Dougan, Gordon; Hasan, Rumina

Transcriptomic Characterization of Tuberculous Sputum Reveals a Host Warburg Effect and Microbial Cholesterol Catabolism. (2021) Lai, Rachel PJ; Cortes, Teresa; Marais, Suzaan; Rockwood, Neesha; Burke, Melissa L; Garza-Garcia, Acely; Horswell, Stuart; Sesay, Abdul K; O'Garra, Anne; Young, Douglas B; Wilkinson, Robert J

Immune Imprinting Drives Human Norovirus Potential for Global Spread. (2022) Lindesmith, Lisa C; Boshier, Florencia AT; Brewer-Jensen, Paul D; Roy, Sunando; Costantini, Veronica; Mallory, Michael L; Zweigart, Mark; May, Samantha R; Conrad, Helen; O'Reilly, Kathleen M; Kelly, Daniel; Celma, Cristina C; Beard, Stuart; Williams, Rachel; Tutill, Helena J; Becker Dreps, Sylvia; Bucardo, Filemón; Allen, David J; Vinjé, Jan; Goldstein, Richard A; Breuer, Judith; Baric, Ralph S

Deletion of Plasmodium falciparum Protein RON3 Affects the Functional Translocation of Exported Proteins and Glucose Uptake. (2019) Low, Leanne M; Azasi, Yvonne; Sherling, Emma S; Garten, Matthias; Zimmerberg, Joshua; Tsuboi, Takafumi; Brzostowski, Joseph; Mu, Jianbing; Blackman, Michael J; Miller, Louis H

One Health Genomic Surveillance of Escherichia coli Demonstrates Distinct Lineages and Mobile Genetic Elements in Isolates from Humans versus Livestock. (2019) Ludden, Catherine; Raven, Kathy E; Jamrozy, Dorota; Gouliouris, Theodore; Blane, Beth; Coll, Francesc; de Goffau, Marcus; Naydenova, Plamena; Horner, Carolyne; Hernandez-Garcia, Juan; Wood, Paul; Hadjirin, Nazreen; Radakovic, Milorad; Brown, Nicholas M; Holmes, Mark; Parkhill, Julian; Peacock, Sharon J

Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive Escherichia coli. (2023) Miles, Sydney L; Torraca, Vincenzo; Dyson, Zoe A; López-Jiménez, Ana Teresa; Foster-Nyarko, Ebenezer; Lobato-Márquez, Damián; Jenkins, Claire; Holt, Kathryn E; Mostowy, Serge

Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs. (2022) Mohring, Franziska; van Schalkwyk, Donelly A; Henrici, Ryan C; Blasco, Benjamin; Leroy, Didier; Sutherland, Colin J; Moon, Robert W

Evolution of the Staphylococcus argenteus ST2250 Clone in Northeastern Thailand Is Linked with the Acquisition of Livestock-Associated Staphylococcal Genes. (2017) Moradigaravand, Danesh; Jamrozy, Dorota; Mostowy, Rafal; Anderson, Annaliesa; Nickerson, Emma K; Thaipadungpanit, Janjira; Wuthiekanun, Vanaporn; Limmathurotsakul, Direk; Tandhavanant, Sarunporn; Wikraiphat, Chanthiwa; Wongsuvan, Gumphol; Teerawattanasook, Nittaya; Jutrakul, Yaowaruk; Srisurat, Nuttiya; Chaimanee, Prajuab; Eoin West, T; Blane, Beth; Parkhill, Julian; Chantratita, Narisara; Peacock, Sharon J

Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland. (2017) Moradigaravand, Danesh; Martin, Veronique; Peacock, Sharon J; Parkhill, Julian

Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences. (2016) Mottram, Lynda; Speak, Anneliese O; Selek, Reza M; Cambridge, Emma L; McIntyre, Zoe; Kane, Leanne; Mukhopadhyay, Subhankar; Grove, Carolyn; Colin, Amy; Brandt, Cordelia; Duque-Correa, Maria A; Forbester, Jessica; Nguyen, Tu Anh Pham; Hale, Christine; Vasilliou, George S; Arends, Mark J; Wren, Brendan W; Dougan, Gordon; Clare, Simon

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. (2014) Moule, Madeleine G; Hemsley, Claudia M; Seet, Qihui; Guerra-Assunção, José Afonso; Lim, Jiali; Sarkar-Tyson, Mitali; Clark, Taane G; Tan, Patrick BO; Titball, Richard W; Cuccui, Jon; Wren, Brendan W

High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks. (2017) Netto, Eduardo Martins; Moreira-Soto, Andres; Pedroso, Celia; Höser, Christoph; Funk, Sebastian; Kucharski, Adam J; Rockstroh, Alexandra; Kümmerer, Beate M; Sampaio, Gilmara Souza; Luz, Estela; Vaz, Sara Nunes; Dias, Juarez Pereira; Bastos, Fernanda Anjos; Cabral, Renata; Kistemann, Thomas; Ulbert, Sebastian; de Lamballerie, Xavier; Jaenisch, Thomas; Brady, Oliver J; Drosten, Christian; Sarno, Manoel; Brites, Carlos; Drexler, Jan Felix

A novel micronemal protein MP38 is involved in the invasion of merozoites into erythrocytes. (2025) Nguyen, Tuyet-Kha; Nguyen, Sy-Thau; Nguyen, Van-Truong; Na, Sung-Hun; Moon, Robert W; Sattabongkot, Jetsumon; Lau, Yee Ling; Park, Won-Sun; Chun, Wan-Joo; Lu, Feng; Lee, Seong-Kyun; Han, Jin-Hee; Han, Eun-Taek

Plasmodium falciparum Guanylyl Cyclase-Alpha and the Activity of Its Appended P4-ATPase Domain Are Essential for cGMP Synthesis and Blood-Stage Egress. (2021) Nofal, Stephanie D; Patel, Avnish; Blackman, Michael J; Flueck, Christian; Baker, David A

Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development. (2024) Patel, Avnish; Fréville, Aline; Rey, Joshua A; Flynn, Helen R; Koussis, Konstantinos; Skehel, Mark J; Blackman, Michael J; Baker, David A

CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation. (2022) Patel, Avnish; Nofal, Stephanie D; Blackman, Michael J; Baker, David A

Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony. (2021) Perrin, Abigail J; Bisson, Claudine; Faull, Peter A; Renshaw, Matthew J; Lees, Rebecca A; Fleck, Roland A; Saibil, Helen R; Snijders, Ambrosius P; Baker, David A; Blackman, Michael J

The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress. (2018) Perrin, Abigail J; Collins, Christine R; Russell, Matthew RG; Collinson, Lucy M; Baker, David A; Blackman, Michael J

Erratum for Pettersson et al., "How Did Zika Virus Emerge in the Pacific Islands and Latin America?". (2018) Pettersson, John H-O; Eldholm, Vegard; Seligman, Stephen J; Lundkvist, Åke; Falconar, Andrew K; Gaunt, Michael W; Musso, Didier; Nougairède, Antoine; Charrel, Remi; Gould, Ernest A; de Lamballerie, Xavier

How Did Zika Virus Emerge in the Pacific Islands and Latin America? (2016) Pettersson, John H-O; Eldholm, Vegard; Seligman, Stephen J; Lundkvist, Åke; Falconar, Andrew K; Gaunt, Michael W; Musso, Didier; Nougairède, Antoine; Charrel, Remi; Gould, Ernest A; de Lamballerie, Xavier

A patatin-like phospholipase is important for mitochondrial function in malaria parasites. (2023) Pietsch, Emma; Ramaprasad, Abhinay; Bielfeld, Sabrina; Wohlfarter, Yvonne; Maco, Bohumil; Niedermüller, Korbinian; Wilcke, Louisa; Kloehn, Joachim; Keller, Markus A; Soldati-Favre, Dominique; Blackman, Michael J; Gilberger, Tim-Wolf; Burda, Paul-Christian

Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae. (2024) Ramos-Sevillano, Elisa; Ercoli, Giuseppe; Betts, Modupeh; Guerra-Assunção, José Afonso; Iverson, Amy; Frank, Matthew; Partridge, Frederick; Lo, Stephanie W; Fernandes, Vitor E; Nasher, Fauzy; Wall, Emma; Wren, Brendan; Gordon, Stephen B; Ferreira, Daniela M; Heyderman, Rob; Rosch, Jason; Brown, Jeremy S

Exploiting Real-Time Genomic Surveillance Data To Assess 4CMenB Meningococcal Vaccine Performance in Scotland, 2015 to 2022. (2023) Rodrigues, CMC; MacDonald, L; Ure, R; Smith, A; Cameron, JC; Maiden, MCJ

The Stealthy Superbug: the Role of Asymptomatic Enteric Carriage in Maintaining a Long-Term Hospital Outbreak of ST228 Methicillin-Resistant Staphylococcus aureus. (2016) Senn, Laurence; Clerc, Olivier; Zanetti, Giorgio; Basset, Patrick; Prod'hom, Guy; Gordon, Nicola C; Sheppard, Anna E; Crook, Derrick W; James, Richard; Thorpe, Harry A; Feil, Edward J; Blanc, Dominique S

Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus. (2019) Sewell, Thomas R; Zhu, Jianing; Rhodes, Johanna; Hagen, Ferry; Meis, Jacques F; Fisher, Matthew C; Jombart, Thibaut

Integration of genomic and pharmacokinetic data to predict clinical outcomes in HIV-associated cryptococcal meningitis. (2024) Stott, Katharine E; Mohabir, Jason T; Bowers, Katharine; Tenor, Jennifer L; Toffaletti, Dena L; Unsworth, Jennifer; Jimenez-Valverde, Ana; Ahmadu, Ajisa; Moyo, Melanie; Gondwe, Ebbie; Chimang'anga, Wezi; Chasweka, Madalitso; Lawrence, David S; Jarvis, Joseph N; Harrison, Tom; Hope, William; Lalloo, David G; Mwandumba, Henry C; Perfect, John R; Cuomo, Christina A; AMBITION Study Group

Genetic and Structural Variation in the O-Antigen of Salmonella enterica Serovar Typhimurium Isolates Causing Bloodstream Infections in the Democratic Republic of the Congo. (2022) Van Puyvelde, Sandra; Gasperini, Gianmarco; Biggel, Michael; Phoba, Marie-France; Raso, Maria Michelina; de Block, Tessa; Vanheer, Leen N; Deborggraeve, Stijn; Vandenberg, Olivier; Thomson, Nicholas; Ravenscroft, Neil; Maclennan, Calman A; Bellich, Barbara; Cescutti, Paola; Dougan, Gordon; Jacobs, Jan; Lunguya, Octavie; Micoli, Francesca

In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution. (2020) Ward, Alexander I; Lewis, Michael D; Khan, Archie A; McCann, Conor J; Francisco, Amanda F; Jayawardhana, Shiromani; Taylor, Martin C; Kelly, John M

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation. (2019) Watson, Jayne L; Sanchez-Garrido, Julia; Goddard, Philippa J; Torraca, Vincenzo; Mostowy, Serge; Shenoy, Avinash R; Clements, Abigail

Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection. (2018) Willis, Alexandra R; Torraca, Vincenzo; Gomes, Margarida C; Shelley, Jennifer; Mazon-Moya, Maria; Filloux, Alain; Lo Celso, Cristina; Mostowy, Serge

The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH. (2012) Wong, Alexander RC; Clements, Abigail; Raymond, Benoit; Crepin, Valerie F; Frankel, Gad