Bissett, Sara L; Roy, Polly; (2024) Multi-Gene Recombinant Baculovirus Expression Systems: From Inception to Contemporary Applications. Viruses, 16 (4). p. 492. ISSN 1999-4915 DOI: https://doi.org/10.3390/v16040492

Sung, Po-Yu; Phelan, Jody E; Luo, Dongsheng; Kulasegaran-Shylini, Raghavendran; Bohn, Patrick; Smyth, Redmond P; Roy, Polly; (2024) Recruitment of multi-segment genomic RNAs by Bluetongue virus requires a preformed RNA network. Nucleic acids research, 52 (14). pp. 8500-8514. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gkae404

Sung, Po-Yu; Zhou, Yiyang; Kao, C Cheng; Aburigh, Ali A; Routh, Andrew; Roy, Polly; (2023) A multidisciplinary approach to the identification of the protein-RNA connectome in double-stranded RNA virus capsids. Nucleic acids research, 51 (10). pp. 5210-5227. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gkad274

Rahman, Shah Kamranur; Ampah, Khamal Kwesi; Roy, Polly; (2022) Role of NS2 specific RNA binding and phosphorylation in liquid-liquid phase separation and virus assembly. Nucleic Acids Research, 50 (19). pp. 11273-11284. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gkac904

Sullivan, Edward; Sung, Po-Yu; Wu, Weining; Berry, Neil; Kempster, Sarah; Ferguson, Deborah; Almond, Neil; Jones, Ian M; Roy, Polly; (2022) SARS-CoV-2 Virus-like Particles Produced by a Single Recombinant Baculovirus Generate Anti-S Antibody and Protect against Variant Challenge. Viruses, 14 (5). p. 914. ISSN 1999-4915 DOI: https://doi.org/10.3390/v14050914

Jones, Ian; Roy, Polly; (2021) Small is beautiful: virus-like particles as vaccines. The Biochemist, 43 (4). pp. 18-21. ISSN 0954-982X DOI: https://doi.org/10.1042/bio_2021_153

Jones, Ian; Roy, Polly; (2021) Sputnik V COVID-19 vaccine candidate appears safe and effective. Lancet, 397 (10275). pp. 642-643. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(21)00191-4

Sullivan, Edward; Lecollinet, Sylvie; Kerviel, Adeline; Hue, Erika; Pronost, Stéphane; Beck, Cécile; Dumarest, Marine; Zientara, Stephan; Roy, Polly; (2021) Entry-competent-replication-abortive African horse sickness virus strains elicit robust immunity in ponies against all serotypes. Vaccine, 39 (23). pp. 3161-3168. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2021.04.034

Sung, Po-Yu; Roy, Polly; (2021) RNA Origami: Packaging a Segmented Genome in Orbivirus Assembly and Replication. Viruses, 13 (9). p. 1841. ISSN 1999-4915 DOI: https://doi.org/10.3390/v13091841

Wu, Weining; Roy, Polly; (2021) Sialic Acid Binding Sites in VP2 of Bluetongue Virus and Their Use during Virus Entry. Journal of virology, 96 (1). e0167721-. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01677-21

Xia, Xian; Wu, Weining; Cui, Yanxiang; Roy, Polly; Zhou, Z Hong; (2021) Bluetongue virus capsid protein VP5 perforates membranes at low endosomal pH during viral entry. Nat Microbiol, 6 (11). pp. 1424-1432. DOI: https://doi.org/10.1038/s41564-021-00988-8

Labadie, Thomas; Roy, Polly; (2020) A non-enveloped arbovirus released in lysosome-derived extracellular vesicles induces super-infection exclusion. PLOS PATHOGENS, 16 (10). e1009015-. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1009015

Labadie, Thomas; Sullivan, Edward; Roy, Polly; (2020) Multiple Routes of Bluetongue Virus Egress. MICROORGANISMS, 8 (7). p. 965. ISSN 2076-2607 DOI: https://doi.org/10.3390/microorganisms8070965

Mohl, Bjorn-Patrick; Kerviel, Adeline; Labadie, Thomas; Matsuo, Eiko; Roy, Polly; (2020) Differential Localization of Structural and Non-Structural Proteins during the Bluetongue Virus Replication Cycle. VIRUSES-BASEL, 12 (3). p. 343. ISSN 1999-4915 DOI: https://doi.org/10.3390/v12030343

Rahman, Shah Kamranur; Kerviel, Adeline; Mohl, Bjorn-Patrick; He, Yao; Zhou, Z Hong; Roy, Polly; (2020) A Calcium Sensor Discovered in Bluetongue Virus Nonstructural Protein 2 Is Critical for Virus Replication. Journal of Virology, 94 (20). JVI.01099-20. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01099-20

Roy, Polly; (2020) Highly efficient vaccines for Bluetongue virus and a related Orbivirus based on reverse genetics. CURRENT OPINION IN VIROLOGY, 44. pp. 35-41. ISSN 1879-6257 DOI: https://doi.org/10.1016/j.coviro.2020.05.003

Ding, Ke; Celma, Cristina C; Zhang, Xing; Chang, Thomas; Shen, Wesley; Atanasov, Ivo; Roy, Polly; Zhou, Z Hong; (2019) In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nature communications, 10 (1). 2216-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-019-10236-7

He, Yao; Shivakoti, Sakar; Ding, Ke; Cui, Yanxiang; Roy, Polly; Zhou, Z Hong; (2019) In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proceedings of the National Academy of Sciences, 116 (33). pp. 16535-16540. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1905849116

Kerviel, Adeline; Ge, Peng; Lai, Mason; Jih, Jonathan; Boyce, Mark; Zhang, Xing; Zhou, Hong; Roy, Polly; (2019) Atomic structure of the translation regulatory protein NS1 of bluetongue virus. Nature Microbiology, 4 (5). pp. 837-845. ISSN 2058-5276 DOI: https://doi.org/10.1038/s41564-019-0369-x

Labadie, Thomas; Jegouic, Sophie; Roy, Polly; (2019) Bluetongue Virus Nonstructural Protein 3 Orchestrates Virus Maturation and Drives Non-Lytic Egress via Two Polybasic Motifs. Viruses, 11 (12). p. 1107. ISSN 1999-4915 DOI: https://doi.org/10.3390/v11121107

Mohl, Bjorn-Patrick; Roy, Polly; (2019) Hsp90 Chaperones Bluetongue Virus Proteins and Prevents Proteasomal Degradation. Journal of virology, 93 (20). e00898-19. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.00898-19

Wu, Weining; Celma, Cristina C; Kerviel, Adeline; Roy, Polly; (2019) Mapping the pH Sensors Critical for Host Cell Entry by a Complex Nonenveloped Virus. Journal of virology, 93 (4). e01897-18. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01897-18

AlShaikhahmed, Kinda; Leonov, German; Sung, Po-Yu; Bingham, Richard J; Twarock, Reidun; Roy, Polly; (2018) Dynamic network approach for the modelling of genomic sub-complexes in multi-segmented viruses. Nucleic acids research, 46 (22). pp. 12087-12098. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gky881

Li, Siyu; Roy, Polly; Travesset, Alex; Zandi, Roya; (2018) Why large icosahedral viruses need scaffolding proteins. Proceedings of the National Academy of Sciences of the United States of America, 115 (43). pp. 10971-10976. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1807706115 Full text not available from this repository.

Sung, Po-Yu; Vaughan, Robert; Rahman, Shah Kamranur; Yi, Guanghui; Kerviel, Adeline; Kao, C Cheng; Roy, Polly; (2018) The Interaction of Bluetongue Virus VP6 and Genomic RNA Is Essential for Genome Packaging. Journal of virology, 93 (5). ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.02023-18

Fajardo, Teodoro; Sung, Po-Yu; Celma, Cristina C; Roy, Polly; (2017) Rotavirus Genomic RNA Complex Forms via Specific RNA-RNA Interactions: Disruption of RNA Complex Inhibits Virus Infectivity. Viruses, 9 (7). p. 167. ISSN 1999-4915 DOI: https://doi.org/10.3390/v9070167

Lulla, Valeria; Losada, Andres; Lecollinet, Sylvie; Kerviel, Adeline; Lilin, Thomas; Sailleau, Corinne; Beck, Cecile; Zientara, Stephan; Roy, Polly; (2017) Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge. Vaccine, 35 (33). pp. 4262-4269. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2017.06.023

Matsuo, Eiko; Yamazaki, Kiyoshi; Tsuruta, Hiroki; Roy, Polly; (2017) Interaction between a Unique Minor Protein and a Major Capsid Protein of Bluetongue Virus Controls Virus Infectivity. Journal of virology, 92 (3). ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01784-17

Mohl, Bjorn-Patrick; Emmott, Edward; Roy, Polly; (2017) Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection. Molecular & cellular proteomics, 16 (11). pp. 1990-2005. ISSN 1535-9476 DOI: https://doi.org/10.1074/mcp.M117.067355

Mohl, Bjorn-Patrick; Roy, Polly; (2017) Elucidating virus entry using a tetracysteine-tagged virus. Methods (San Diego, Calif), 127. pp. 23-29. ISSN 1046-2023 DOI: https://doi.org/10.1016/j.ymeth.2017.08.004

Roy, P; (2017) Bluetongue virus structure and assembly. Current opinion in virology, 24. pp. 115-123. ISSN 1879-6257 DOI: https://doi.org/10.1016/j.coviro.2017.05.003

Alshaikhahmed, Kinda; Roy, Polly; (2016) Generation of virus-like particles for emerging epizootic haemorrhagic disease virus: Towards the development of safe vaccine candidates. Vaccine, 34 (8). pp. 1103-1108. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2015.12.069 Full text not available from this repository.

Celma, Cristina C; Stewart, Meredith; Wernike, Kerstin; Eschbaumer, Michael; Gonzalez-Molleda, Lorenzo; Breard, Emmanuel; Schulz, Claudia; Hoffmann, Bernd; Haegeman, Andy; De Clercq, Kris; +4 more... Zientara, Stephan; van Rijn, Piet A; Beer, Martin; Roy, Polly; (2016) Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines. Journal of virology, 91 (1). ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01892-16

Fajardo, Teodoro; AlShaikhahmed, Kinda; Roy, Polly; (2016) Generation of infectious RNA complexes in Orbiviruses: RNA-RNA interactions of genomic segments. Oncotarget, 7 (45). pp. 72559-72570. ISSN 1949-2553 DOI: https://doi.org/10.18632/oncotarget.12496

Lulla, Valeria; Lulla, Aleksei; Wernike, Kerstin; Aebischer, Andrea; Beer, Martin; Roy, Polly; (2016) Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes. Journal of virology, 90 (16). pp. 7405-7414. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.00548-16

Mohl, Bjorn-Patrick; Roy, Polly; (2016) Cellular Casein Kinase 2 and Protein Phosphatase 2A Modulate Replication Site Assembly of Bluetongue Virus. The Journal of biological chemistry, 291 (28). pp. 14566-14574. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M116.714766

Patel, Avnish; Mohl, Bjorn-Patrick; Roy, Polly; (2016) Entry of Bluetongue Virus Capsid Requires the Late Endosome-specific Lipid Lysobisphosphatidic Acid. The Journal of biological chemistry, 291 (23). pp. 12408-12419. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M115.700856

AlShaikhahmed, K; (2015) Developing Virus-Like Particles (VLPs) and Heterologous VLPs Vaccines for Epizootic Hemorrhagic Disease Virus (EHDV) Serotypes. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.02172948

Bhattacharya, Bishnupriya; Celma, Cristina C; Roy, Polly; (2015) Influence of cellular trafficking pathway on bluetongue virus infection in ovine cells. VIRUSES-BASEL, 7 (5). pp. 2378-2403. ISSN 1999-4915 DOI: https://doi.org/10.3390/v7052378

Fajardo, Teodoro; Sung, Po-Yu; Roy, Polly; (2015) Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity. PLoS pathogens, 11 (12). e1005321-. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1005321

Matsuo, Eiko; Saeki, Keiichi; Roy, Polly; Kawano, Junichi; (2015) Development of reverse genetics for Ibaraki virus to produce viable VP6-tagged IBAV. FEBS open bio, 5 (1). pp. 445-453. ISSN 2211-5463 DOI: https://doi.org/10.1016/j.fob.2015.05.006

Stewart, Meredith E; Roy, Polly; (2015) Structure-based identification of functional residues in the nucleoside-2'-O-methylase domain of Bluetongue virus VP4 capping enzyme. FEBS open bio, 5 (1). pp. 138-146. ISSN 2211-5463 DOI: https://doi.org/10.1016/j.fob.2015.02.001

Zhang, Xing; Patel, Avnish; Celma, Cristina C; Yu, Xuekui; Roy, Polly; Zhou, Z Hong; (2015) Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry. Nature structural & molecular biology, 23 (1). pp. 74-80. ISSN 1545-9993 DOI: https://doi.org/10.1038/nsmb.3134

Burkhardt, Christiane; Sung, Po-Yu; Celma, Cristina C; Roy, Polly; (2014) Structural constraints in the packaging of bluetongue virus genomic segments. The Journal of general virology, 95 (Pt 10). pp. 2240-2250. ISSN 0022-1317 DOI: https://doi.org/10.1099/vir.0.066647-0

Celma, Cristina C; Bhattacharya, Bishnupriya; Eschbaumer, Michael; Wernike, Kerstin; Beer, Martin; Roy, Polly; (2014) Pathogenicity study in sheep using reverse-genetics-based reassortant bluetongue viruses. Veterinary microbiology, 174 (1-2). pp. 139-147. ISSN 0378-1135 DOI: https://doi.org/10.1016/j.vetmic.2014.09.012

Du, Junzheng; Bhattacharya, Bishnupriya; Ward, Theresa H; Roy, Polly; (2014) Trafficking of bluetongue virus visualized by recovery of tetracysteine-tagged virion particles. Journal of virology, 88 (21). pp. 12656-12668. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01815-14 Full text not available from this repository.

Kanai, Yuta; van Rijn, Piet A; Maris-Veldhuis, Mieke; Kaname, Yuki; Athmaram, TN; Roy, Polly; (2014) Immunogenicity of recombinant VP2 proteins of all nine serotypes of African horse sickness virus. Vaccine, 32 (39). pp. 4932-4937. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2014.07.031

Matsuo, Eiko; Leon, Esther; Matthews, Steve J; Roy, Polly; (2014) Structure based modification of Bluetongue virus helicase protein VP6 to produce a viable VP6-truncated BTV. Biochemical and biophysical research communications, 451 (4). pp. 603-608. ISSN 0006-291X DOI: https://doi.org/10.1016/j.bbrc.2014.08.028

Mohl, Bjorn-Patrick; Roy, Polly; (2014) Bluetongue virus capsid assembly and maturation. Viruses, 6 (8). pp. 3250-3270. ISSN 1999-4915 DOI: https://doi.org/10.3390/v6083250

Sung, Po-Yu; Roy, Polly; (2014) Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. Nucleic acids research, 42 (22). pp. 13824-13838. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gku1171

Andrade, Sara; Pinho, Filipa; Ribeiro, Andreia M; Carreira, Marcos; Casanueva, Felipe F; Roy, Polly; Monteiro, Mariana P; (2013) Immunization against active ghrelin using virus-like particles for obesity treatment. Current pharmaceutical design, 19 (36). pp. 6551-6558. ISSN 1381-6128 DOI: https://doi.org/10.2174/13816128113199990506

Bhattacharya, Bishnupriya; Roy, Polly; (2013) Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. Virology journal, 10 (1). 73-. ISSN 1743-422X DOI: https://doi.org/10.1186/1743-422X-10-73

Celma, Cristina CP; Boyce, Mark; van Rijn, Piet A; Eschbaumer, Michael; Wernike, Kerstin; Hoffmann, Bernd; Beer, Martin; Haegeman, Andy; De Clercq, Kris; Roy, Polly; (2013) Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep. Journal of virology, 87 (17). pp. 9856-9864. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01514-13 Full text not available from this repository.

Kanai, Yuta; Athmaram, TN; Stewart, Meredith; Roy, Polly; (2013) Multiple large foreign protein expression by a single recombinant baculovirus: a system for production of multivalent vaccines. Protein expression and purification, 91 (1). pp. 77-84. ISSN 1046-5928 DOI: https://doi.org/10.1016/j.pep.2013.07.005 Full text not available from this repository.

Kaname, Yuuki; Celma, Cristina CP; Kanai, Yuta; Roy, Polly; (2013) Recovery of African horse sickness virus from synthetic RNA. The Journal of general virology, 94 (Pt 10). pp. 2259-2265. ISSN 0022-1317 DOI: https://doi.org/10.1099/vir.0.055905-0 Full text not available from this repository.

Matsuo, Eiko; Roy, Polly; (2013) Minimum requirements for bluetongue virus primary replication in vivo. Journal of virology, 87 (2). pp. 882-889. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.02363-12 Full text not available from this repository.

Patel, Avnish; Roy, Polly; (2013) The molecular biology of Bluetongue virus replication. Virus research, 182. pp. 5-20. ISSN 0168-1702 DOI: https://doi.org/10.1016/j.virusres.2013.12.017 Full text not available from this repository.

Periz, Javier; Celma, Cristina; Jing, Bo; Pinkney, Justin NM; Roy, Polly; Kapanidis, Achillefs N; (2013) Rotavirus mRNAS are released by transcript-specific channels in the double-layered viral capsid. Proceedings of the National Academy of Sciences of the United States of America, 110 (29). pp. 12042-12047. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1220345110 Full text not available from this repository.

Roy, Polly; (2013) Orbiviruses. In: Knipe, DM; Howley, PM, (eds.) Fields' Virology. Lippincott Williams & Wilkins, Philadelphia, USA., pp. 1402-1423. https://researchonline.lshtm.ac.uk/id/eprint/4650194 Full text not available from this repository.

Stewart, Meredith; Dubois, Eric; Sailleau, Corinne; Bréard, Emmanuel; Viarouge, Cyril; Desprat, Alexandra; Thiéry, Richard; Zientara, Stéphan; Roy, Polly; (2013) Bluetongue virus serotype 8 virus-like particles protect sheep against virulent virus infection as a single or multi-serotype cocktail immunogen. Vaccine, 31 (3). pp. 553-558. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2012.11.016 Full text not available from this repository.

Boyce, Mark; Celma, Cristina CP; Roy, Polly; (2012) Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. Virology journal, 9 (1). 178-. ISSN 1743-422X DOI: https://doi.org/10.1186/1743-422X-9-178

Dautu, George; Sindato, Calvin; Mweene, Aaron S; Samui, Kenny L; Roy, Polly; Noad, Robert; Paweska, Janusz; Majiwa, Phelix AO; Musoke, Antony; (2012) Rift Valley fever: Real or perceived threat for Zambia? [Conference or Workshop Item] https://doi.org/10.4102/ojvr.v79i2.466 Full text not available from this repository.

Roy, Polly; Noad, Rob; (2012) Use of bacterial artificial chromosomes in baculovirus research and recombinant protein expression: current trends and future perspectives. ISRN microbiology, 2012. 628797-. ISSN 2090-7478 DOI: https://doi.org/10.5402/2012/628797

Ruscanu, Suzana; Pascale, Florentina; Bourge, Mickael; Hemati, Behzad; Elhmouzi-Younes, Jamila; Urien, Céline; Bonneau, Michel; Takamatsu, Haru; Hope, Jayne; Mertens, Peter; +12 more... Meyer, Gilles; Stewart, Meredith; Roy, Polly; Meurs, Eliane F; Dabo, Stéphanie; Zientara, Stéphan; Breard, Emmanuel; Sailleau, Corinne; Chauveau, Emilie; Vitour, Damien; Charley, Bernard; Schwartz-Cornil, Isabelle; (2012) The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway. Journal of virology, 86 (10). pp. 5817-5828. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.06716-11 Full text not available from this repository.

Stewart, M; Dovas, CI; Chatzinasiou, E; Athmaram, TN; Papanastassopoulou, M; Papadopoulos, O; Roy, P; (2012) Protective efficacy of Bluetongue virus-like and subvirus-like particles in sheep: presence of the serotype-specific VP2, independent of its geographic lineage, is essential for protection. Vaccine, 30 (12). pp. 2131-2139. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2012.01.042 Full text not available from this repository.

Celma, Cristina CP; Roy, Polly; (2011) Interaction of calpactin light chain (S100A10/p11) and a viral NS protein is essential for intracellular trafficking of nonenveloped bluetongue virus. Journal of virology, 85 (10). pp. 4783-4791. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.02352-10 Full text not available from this repository.

Lourenco, Sofia; Roy, Polly; (2011) In vitro reconstitution of Bluetongue virus infectious cores. Proceedings of the National Academy of Sciences of the United States of America, 108 (33). pp. 13746-13751. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1108667108 Item availability may be restricted.

Matsuo, Eiko; Celma, Cristina CP; Boyce, Mark; Viarouge, Cyril; Sailleau, Corinne; Dubois, Eric; Bréard, Emmanuel; Thiéry, Richard; Zientara, Stéphan; Roy, Polly; (2011) Generation of replication-defective virus-based vaccines that confer full protection in sheep against virulent bluetongue virus challenge. Journal of virology, 85 (19). pp. 10213-10221. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.05412-11 Full text not available from this repository.

Matsuo, Eiko; Roy, Polly; (2011) Bluetongue virus VP1 polymerase activity in vitro: template dependency, dinucleotide priming and cap dependency. PloS one, 6 (11). e27702-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0027702

Pérez de Diego, Ana Cristina; Athmaram, Thimmasandra N; Stewart, Meredith; Rodríguez-Sánchez, Belén; Sánchez-Vizcaíno, José Manuel; Noad, Robert; Roy, Polly; (2011) Characterization of protection afforded by a bivalent virus-like particle vaccine against bluetongue virus serotypes 1 and 4 in sheep. PloS one, 6 (10). e26666-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0026666

LSHTM; (2010) Bluetongue Disease Of Sheep: Two New Vaccines On The Way - 12 February 2010. [Podcast] http://soundcloud.com/lshtm/bluetongue-disease-of-...

Bhattacharya, Bishnupriya; Roy, Polly; (2010) Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus. Viruses, 2 (5). pp. 1218-1235. ISSN 1999-4915 DOI: https://doi.org/10.3390/v2051218

Drew, Clifton P; Gardner, Ian A; Mayo, Christie E; Matsuo, Eiko; Roy, Polly; MacLachlan, N James; (2010) Bluetongue virus infection alters the impedance of monolayers of bovine endothelial cells as a result of cell death. Veterinary immunology and immunopathology, 136 (1-2). pp. 108-115. ISSN 0165-2427 DOI: https://doi.org/10.1016/j.vetimm.2010.03.005

Matsuo, Eiko; Celma, Cristina CP; Roy, Polly; (2010) A reverse genetics system of African horse sickness virus reveals existence of primary replication. FEBS letters, 584 (15). pp. 3386-3391. ISSN 0014-5793 DOI: https://doi.org/10.1016/j.febslet.2010.06.030 Full text not available from this repository.

Stewart, Meredith E; Roy, Polly; (2010) Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate. Virology journal, 7 (1). 362-. ISSN 1743-422X DOI: https://doi.org/10.1186/1743-422X-7-362

Zhang, Xing; Boyce, Mark; Bhattacharya, Bishnupriya; Zhang, Xiaokang; Schein, Stan; Roy, Polly; Zhou, Z Hong; (2010) Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins. Proceedings of the National Academy of Sciences of the United States of America, 107 (14). pp. 6292-6297. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0913403107 Full text not available from this repository.

Allen, David J; Noad, Rob; Samuel, Dhan; Gray, Jim J; Roy, Polly; Iturriza-Gómara, Miren; (2009) Characterisation of a GII-4 norovirus variant-specific surface-exposed site involved in antibody binding. Virology journal, 6 (1). 150-. ISSN 1743-422X DOI: https://doi.org/10.1186/1743-422X-6-150

Celma, Cristina CP; Roy, Polly; (2009) A viral nonstructural protein regulates bluetongue virus trafficking and release. Journal of virology, 83 (13). pp. 6806-6816. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.00263-09 Full text not available from this repository.

Martínez-Alonso, Mónica; Toledo-Rubio, Verónica; Noad, Rob; Unzueta, Ugutz; Ferrer-Miralles, Neus; Roy, Polly; Villaverde, Antonio; (2009) Rehosting of bacterial chaperones for high-quality protein production. Applied and environmental microbiology, 75 (24). pp. 7850-7854. ISSN 0099-2240 DOI: https://doi.org/10.1128/AEM.01532-09 Full text not available from this repository.

Matsuo, Eiko; Roy, Polly; (2009) Bluetongue virus VP6 acts early in the replication cycle and can form the basis of chimeric virus formation. Journal of virology, 83 (17). pp. 8842-8848. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.00465-09 Full text not available from this repository.

Noad, R; Roy, P; (2009) Bluetongue vaccines. Vaccine, 27 Sup (SUPPL.). D86-D89. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2009.08.037 Full text not available from this repository.

Noad, Rob J; Stewart, Meredith; Boyce, Mark; Celma, Cristina C; Willison, Keith R; Roy, Polly; (2009) Multigene expression of protein complexes by iterative modification of genomic Bacmid DNA. BMC molecular biology, 10 (1). 87-. ISSN 1471-2199 DOI: https://doi.org/10.1186/1471-2199-10-87

Roy, Polly; Boyce, Mark; Noad, Robert; (2009) Prospects for improved bluetongue vaccines. Nature reviews Microbiology, 7 (2). pp. 120-128. ISSN 1740-1526 DOI: https://doi.org/10.1038/nrmicro2052 Full text not available from this repository.

Roy, Polly; Noad, Rob; (2009) Virus-like particles as a vaccine delivery system: myths and facts. Advances in experimental medicine and biology, 655. pp. 145-158. ISSN 0065-2598 DOI: https://doi.org/10.1007/978-1-4419-1132-2_11 Full text not available from this repository.

Stewart, M; Bhatia, Y; Athmaran, TN; Noad, R; Gastaldi, C; Dubois, E; Russo, P; Thiéry, R; Sailleau, C; Bréard, E; +2 more... Zientara, S; Roy, P; (2009) Validation of a novel approach for the rapid production of immunogenic virus-like particles for bluetongue virus. Vaccine, 28 (17). pp. 3047-3054. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2009.10.072 Full text not available from this repository.

Bhattacharya, Bishnupriya; Roy, Polly; (2008) Bluetongue virus outer capsid protein VP5 interacts with membrane lipid rafts via a SNARE domain. Journal of virology, 82 (21). pp. 10600-10612. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01274-08 Full text not available from this repository.

Boyce, Mark; Celma, Cristina CP; Roy, Polly; (2008) Development of reverse genetics systems for bluetongue virus: recovery of infectious virus from synthetic RNA transcripts. Journal of virology, 82 (17). pp. 8339-8348. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.00808-08 Full text not available from this repository.

Liu, Li; Celma, Cristina CP; Roy, Polly; (2008) Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins. Virology journal, 5 (1). 82-. ISSN 1743-422X DOI: https://doi.org/10.1186/1743-422X-5-82

Murphy, Aileen; Roy, Polly; (2008) Manipulation of the bluetongue virus tubules for immunogen delivery. Future microbiology, 3 (3). pp. 351-359. ISSN 1746-0913 DOI: https://doi.org/10.2217/17460913.3.3.351 Full text not available from this repository.

Roy, P; (2008) Molecular Dissection of Bluetongue virus. In: Mettenleiter, TC; Sobrino, F, (eds.) Animal Viruses Molecular Biology. Caister Academic Press, Norfolk, UK, pp. 305-353. ISBN 978-1-904455-22-6 https://researchonline.lshtm.ac.uk/id/eprint/10459 Full text not available from this repository.

Roy, P; (2008) Structure and function of Bluetongue virus and its proteins. In: Patton, JT, (ed.) Segmented Double-stranded RNA Viruses: Structure and Molecular Biology. Caister Academic Press, Norfolk, UK, pp. 61-87. https://researchonline.lshtm.ac.uk/id/eprint/11144 Full text not available from this repository.

Roy, Polly; (2008) Molecular and structural dissection of emerging bluetongue virus as a guide to novel vaccine development. Indian journal of virology, 19 (1). pp. 51-52. ISSN 0970-2822 https://researchonline.lshtm.ac.uk/id/eprint/5879 Full text not available from this repository.

Roy, Polly; (2008) Bluetongue virus: dissection of the polymerase complex. The Journal of general virology, 89 (Pt 8). pp. 1789-1804. ISSN 0022-1317 DOI: https://doi.org/10.1099/vir.0.2008/002089-0 Full text not available from this repository.

Roy, Polly; (2008) Functional mapping of bluetongue virus proteins and their interactions with host proteins during virus replication. Cell biochemistry and biophysics, 50 (3). pp. 143-157. ISSN 1085-9195 DOI: https://doi.org/10.1007/s12013-008-9009-4 Full text not available from this repository.

Roy, Polly; Noad, Rob; (2008) Virus-like particles as a vaccine delivery system: myths and facts. Human vaccines, 4 (1). pp. 5-12. ISSN 1554-8600 DOI: https://doi.org/10.4161/hv.4.1.5559 Full text not available from this repository.

Bhattacharya, Bishnupriya; Noad, Rob J; Roy, Polly; (2007) Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress. Virology journal, 4 (1). 7-. ISSN 1743-422X DOI: https://doi.org/10.1186/1743-422X-4-7

Di Martino, B; Marsilio, F; Roy, P; (2007) Assembly of feline calicivirus-like particle and its immunogenicity. Veterinary microbiology, 120 (1-2). pp. 173-8. ISSN 0378-1135 DOI: https://doi.org/10.1016/j.vetmic.2006.10.021 Full text not available from this repository.

Di Martino, Barbara; Marsilio, Fulvio; Roy, Polly; (2007) Assembly of feline calicivirus-like particle and its immunogenicity. Veterinary microbiology, 120 (1-2). pp. 173-178. ISSN 0378-1135 DOI: https://doi.org/10.1016/j.vetmic.2006.10.021 Full text not available from this repository.

Forzan, Mario; Marsh, Mark; Roy, Polly; (2007) Bluetongue virus entry into cells. Journal of virology, 81 (9). pp. 4819-4827. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.02284-06 Full text not available from this repository.

Kar, Alak Kanti; Bhattacharya, Bishnupriya; Roy, Polly; (2007) Bluetongue virus RNA binding protein NS2 is a modulator of viral replication and assembly. BMC molecular biology, 8 (1). 4-. ISSN 1471-2199 DOI: https://doi.org/10.1186/1471-2199-8-4

Roldão, António; Vieira, Helena LA; Charpilienne, Annie; Poncet, Didier; Roy, Polly; Carrondo, Manuel JT; Alves, Paula M; Oliveira, R; (2007) Modeling rotavirus-like particles production in a baculovirus expression vector system: Infection kinetics, baculovirus DNA replication, mRNA synthesis and protein production. Journal of biotechnology, 128 (4). pp. 875-894. ISSN 0168-1656 DOI: https://doi.org/10.1016/j.jbiotec.2007.01.003 Full text not available from this repository.

Roy, P; (2007) Molecular and structural dissection of an arbovirus as a guide to novel vaccine development. In: Raghunath, D; Durga Rao, C, (eds.) Arthropod Borne Viral Infections Current Status and Research: Proceedings of VIIIth Sir Dorabji Tata Symposium. Tata McGraw_Hill Publishing, New Delhi, Bangalore India, pp. 301-331. ISBN 978-0-07-025177-9 https://researchonline.lshtm.ac.uk/id/eprint/7408 Full text not available from this repository.

Sutton, Geoff; Grimes, Jonathan M; Stuart, David I; Roy, Polly; (2007) Bluetongue virus VP4 is an RNA-capping assembly line. Nature structural & molecular biology, 14 (5). pp. 449-451. ISSN 1545-9993 DOI: https://doi.org/10.1038/nsmb1225 Full text not available from this repository.

Wehrfritz, Josa-marie; Boyce, Mark; Mirza, Sahdia; Roy, Polly; (2007) Reconstitution of bluetongue virus polymerase activity from isolated domains based on a three-dimensional structural model. Biopolymers, 86 (1). pp. 83-94. ISSN 0006-3525 DOI: https://doi.org/10.1002/bip.20706 Full text not available from this repository.

Boyce, Mark; Roy, Polly; (2006) Recovery of infectious bluetongue virus from RNA. Journal of virology, 81 (5). pp. 2179-2186. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.01819-06 Full text not available from this repository.

Lymperopoulos, Kostas; Noad, Rob; Tosi, Sara; Nethisinghe, Suran; Brierley, Ian; Roy, Polly; (2006) Specific binding of Bluetongue virus NS2 to different viral plus-strand RNAs. Virology, 353 (1). pp. 17-26. ISSN 0042-6822 DOI: https://doi.org/10.1016/j.virol.2006.04.022 Full text not available from this repository.

Roy, P; (2006) Orbiviruses. In: Fields, KnipeandHowley, (ed.) Fields Virology (5th Edition). Lippincott Williams and Wilkins, Philadelphia. https://researchonline.lshtm.ac.uk/id/eprint/11498 Full text not available from this repository.

Roy, P; Noad, R; (2006) Bluetongue virus assembly and morphogenesis. In: Roy, P, (ed.) Reoviruses: Entry, Assembly and Morphogenesis. Springer-Verlag Berlin, Berlin, pp. 87-116. ISBN 978-3-540-30772-3 DOI: https://doi.org/10.1007/3-540-30773-7 Full text not available from this repository.

Ward, R; (2006) Bluetongue virus non-structural protein 1: virus-host interactions. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04646527

Wirblich, Christoph; Bhattacharya, Bishnupriya; Roy, Polly; (2006) Nonstructural protein 3 of bluetongue virus assists virus release by recruiting ESCRT-I protein Tsg101. Journal of virology, 80 (1). pp. 460-473. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.80.1.460-473.2006 Full text not available from this repository.

Kar, Alak Kanti; Iwatani, Nao; Roy, Polly; (2005) Assembly and intracellular localization of the bluetongue virus core protein VP3. Journal of virology, 79 (17). pp. 11487-11495. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.79.17.11487-11495.2005 Full text not available from this repository.

Larke, Natasha; Murphy, Aileen; Wirblich, Christoph; Teoh, Denise; Estcourt, Marie J; McMichael, Andrew J; Roy, Polly; Hanke, Tomás; (2005) Induction of human immunodeficiency virus type 1-specific T cells by a bluetongue virus tubule-vectored vaccine prime-recombinant modified virus Ankara boost regimen. Journal of virology, 79 (23). pp. 14822-14833. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.79.23.14822-14833.2005 Full text not available from this repository.

Modrof, Jens; Lymperopoulos, Kostas; Roy, Polly; (2005) Phosphorylation of bluetongue virus nonstructural protein 2 is essential for formation of viral inclusion bodies. Journal of virology, 79 (15). pp. 10023-10031. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.79.15.10023-10031.2005 Full text not available from this repository.

Roy, P; (2005) Bluetongue virus proteins and particles and their role in virus entry, assembly, and release. In: Roy, P, (ed.) Virus Structure and Assembly. Elsevier Academic Press Inc, San Diego, pp. 69-123. ISBN 978-0-12-039863-8 https://researchonline.lshtm.ac.uk/id/eprint/6401 Full text not available from this repository.

Roy, Polly; (2005) Bluetongue virus proteins and particles and their role in virus entry, assembly, and release. Advances in virus research, 64. pp. 69-123. ISSN 0065-3527 DOI: https://doi.org/10.1016/S0065-3527(05)64004-3 Full text not available from this repository.

Boyce, Mark; Wehrfritz, Josa; Noad, Rob; Roy, Polly; (2004) Purified recombinant bluetongue virus VP1 exhibits RNA replicase activity. Journal of virology, 78 (8). pp. 3994-4002. ISSN 0022-538X DOI: https://doi.org/10.1128/jvi.78.8.3994-4002.2004 Full text not available from this repository.

Forzan, Mario; Wirblich, Christoph; Roy, Polly; (2004) A capsid protein of nonenveloped Bluetongue virus exhibits membrane fusion activity. Proceedings of the National Academy of Sciences of the United States of America, 101 (7). pp. 2100-2105. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0306448101 Full text not available from this repository.

Kar, Alak Kanti; Ghosh, Mrinal; Roy, Polly; (2004) Mapping the assembly pathway of Bluetongue virus scaffolding protein VP3. Virology, 324 (2). pp. 387-399. ISSN 0042-6822 DOI: https://doi.org/10.1016/j.virol.2004.04.018 Full text not available from this repository.

Mortola, Eduardo; Noad, Rob; Roy, Polly; (2004) Bluetongue virus outer capsid proteins are sufficient to trigger apoptosis in mammalian cells. Journal of virology, 78 (6). pp. 2875-2883. ISSN 0022-538X DOI: https://doi.org/10.1128/jvi.78.6.2875-2883.2004 Full text not available from this repository.

Mortola, Eduardo; Roy, Polly; (2004) Efficient assembly and release of SARS coronavirus-like particles by a heterologous expression system. FEBS letters, 576 (1-2). pp. 174-178. ISSN 0014-5793 DOI: https://doi.org/10.1016/j.febslet.2004.09.009 Full text not available from this repository.

Nason, Emma L; Rothagel, Rosalba; Mukherjee, Sharmila K; Kar, Alak Kanti; Forzan, Mario; Prasad, BV Venkataram; Roy, Polly; (2004) Interactions between the inner and outer capsids of bluetongue virus. Journal of virology, 78 (15). pp. 8059-8067. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.78.15.8059-8067.2004 Full text not available from this repository.

Owens, Randall J; Limn, Chang; Roy, Polly; (2004) Role of an arbovirus nonstructural protein in cellular pathogenesis and virus release. Journal of virology, 78 (12). pp. 6649-6656. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.78.12.6649-6656.2004 Full text not available from this repository.

Roy, P; (2004) Genetically engineered structure-based vaccine for bluetongue disease. Veterinaria italiana, 40 (4). pp. 594-600. ISSN 0505-401X https://researchonline.lshtm.ac.uk/id/eprint/3802 Full text not available from this repository.

Roy, Polly; (2004) Baculovirus solves a complex problem. Nature biotechnology, 22 (12). pp. 1527-1528. ISSN 1087-0156 DOI: https://doi.org/10.1038/nbt1204-1527 Full text not available from this repository.

Diebold, Sandra S; Montoya, Maria; Unger, Hermann; Alexopoulou, Lena; Roy, Polly; Haswell, Linsey E; Al-Shamkhani, Aymen; Flavell, Richard; Borrow, Persephone; Reis e Sousa, Caetano; (2003) Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature, 424 (6946). pp. 324-328. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature01783 Full text not available from this repository.

Kar, Alak Kanti; Roy, Polly; (2003) Defining the structure-function relationships of bluetongue virus helicase protein VP6. Journal of virology, 77 (21). pp. 11347-11356. ISSN 0022-538X DOI: https://doi.org/10.1128/jvi.77.21.11347-11356.2003 Full text not available from this repository.

Limn, Chang-Kwang; Roy, Polly; (2003) Intermolecular interactions in a two-layered viral capsid that requires a complex symmetry mismatch. Journal of virology, 77 (20). pp. 11114-11124. ISSN 0022-538X DOI: https://doi.org/10.1128/jvi.77.20.11114-11124.2003 Full text not available from this repository.

Lymperopoulos, Kostas; Wirblich, Christoph; Brierley, Ian; Roy, Polly; (2003) Sequence specificity in the interaction of Bluetongue virus non-structural protein 2 (NS2) with viral RNA. The Journal of biological chemistry, 278 (34). pp. 31722-31730. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M301072200 Full text not available from this repository.

Noad, Rob; Roy, Polly; (2003) Virus-like particles as immunogens. Trends in microbiology, 11 (9). pp. 438-444. ISSN 0966-842X DOI: https://doi.org/10.1016/s0966-842x(03)00208-7 Full text not available from this repository.

Roy, P; (2003) Nature and duration of protective immunity to bluetongue virus infection. Developments in biologicals, 114. pp. 169-183. ISSN 1424-6074 https://researchonline.lshtm.ac.uk/id/eprint/15155 Full text not available from this repository.

Beaton, Andrew R; Rodriguez, Javier; Reddy, Y Krishnamohan; Roy, Polly; (2002) The membrane trafficking protein calpactin forms a complex with bluetongue virus protein NS3 and mediates virus release. Proceedings of the National Academy of Sciences of the United States of America, 99 (20). pp. 13154-13159. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.192432299 Full text not available from this repository.

Ghosh, MK; Borca, MV; Roy, Polly; (2002) Virus-derived tubular structure displaying foreign sequences on the surface elicit CD4+ Th cell and protective humoral responses. Virology, 302 (2). pp. 383-392. ISSN 0042-6822 DOI: https://doi.org/10.1006/viro.2002.1648 Full text not available from this repository.

Ghosh, Mrinal K; Dériaud, Edith; Saron, Marie Françoise; Lo-Man, Richard; Henry, Thomas; Jiao, Xinan; Roy, Polly; Leclerc, Claude; (2002) Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences. Vaccine, 20 (9-10). pp. 1369-1377. ISSN 0264-410X DOI: https://doi.org/10.1016/s0264-410x(01)00467-4 Full text not available from this repository.

Ghosh, Mrinal K; Li, Cui-Ling; Fayolle, Catherine; Dadaglio, Gilles; Murphy, Aileen; Lemonnier, François A; Roy, Polly; Leclerc, Claude; (2002) Induction of HLA-A2-restricted CTL responses by a tubular structure carrying human melanoma epitopes. Vaccine, 20 (19-20). pp. 2463-2473. ISSN 0264-410X DOI: https://doi.org/10.1016/s0264-410x(02)00185-8 Full text not available from this repository.

Kakker, Naresh K; Mikhailov, Michael V; Jones, Ian M; Roy, Polly; (2002) Comparative analysis of the roles of simian immunodeficiency and bovine leukemia virus matrix proteins in Gag assembly in insect cells. Virology, 299 (1). pp. 48-55. ISSN 0042-6822 DOI: https://doi.org/10.1006/viro.2002.1441 Full text not available from this repository.

Hassan, SH; Wirblich, C; Forzan, M; Roy, P; (2001) Expression and functional characterization of bluetongue virus VP5 protein: role in cellular permeabilization. Journal of virology, 75 (18). pp. 8356-8367. ISSN 0022-538X DOI: https://doi.org/10.1128/jvi.75.18.8356-8367.2001 Full text not available from this repository.

Tan, BH; Nason, E; Staeuber, N; Jiang, W; Monastryrskaya, K; Roy, P; (2001) RGD tripeptide of bluetongue virus VP7 protein is responsible for core attachment to Culicoides cells. Journal of virology, 75 (8). pp. 3937-3947. ISSN 0022-538X DOI: https://doi.org/10.1128/JVI.75.8.3937-3947.2001 Full text not available from this repository.