Items where Author is "Warhurst, D"

Number of items: 79.
Article
  • In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis. (2002) Adagu, I Sullayman; Nolder, Deborah; Warhurst, David C; Rossignol, Jean-François
  • Field chloroquine-resistance determinants. (1997) Adagu, I; Ogala, W; Carucci, D; Duraisingh, M; Warhurst, D
  • Plasmodium falciparum: linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria. (2001) Adagu, IS; Warhurst, DC
  • Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. (2006) Alifrangis, Michael; Dalgaard, Michael B; Lusingu, John P; Vestergaard, Lasse S; Staalsoe, Trine; Jensen, Anja TR; Enevold, Anders; Rønn, Anita M; Khalil, Insaf F; Warhurst, David C; Lemnge, Martha M; Theander, Thor G; Bygbjerg, Ib C
  • PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX. (2006) Bray, Patrick G; Mungthin, Mathirut; Hastings, Ian M; Biagini, Giancarlo A; Saidu, Dauda K; Lakshmanan, Viswanathan; Johnson, David J; Hughes, Ruth H; Stocks, Paul A; O'Neill, Paul M; Fidock, David A; Warhurst, David C; Ward, Stephen A
  • Mutations in dhfr in Plasmodium falciparum infections selected by chlorproguanil-dapsone treatment. (2002) Curtis, J; Maxwell, CA; Msuya, FHM; Mkongewa, S; Alloueche, A; Warhurst, DC
  • In vitro antiplasmodial activity of extracts of Argentinian plants. (2002) Debenedetti, S; Muschietti, L; van Baren, C; Clavin, M; Broussalis, A; Martino, V; Houghton, PJ; Warhurst, D; Steele, J
  • Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. (2007) Fivelman, QL; Adagu, IS; Warhurst, DC
  • Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum. (2004) Fivelman, Quinton L; Adagu, Ipemida S; Warhurst, David C
  • Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. (2007) Fivelman, Quinton L; Adagu, Ipemida S; Warhurst, David C
  • Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria. (2002) Fivelman, Quinton L; Butcher, Geoffrey A; Adagu, Ipemida S; Warhurst, David C; Pasvol, Geoffrey
  • Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine. (2011) Gadalla, Nahla B; Adam, Ishag; Elzaki, Salah-Eldin; Bashir, Sahar; Mukhtar, Izdihar; Oguike, Mary; Gadalla, Amal; Mansour, Fathi; Warhurst, David; El-Sayed, Badria B; Sutherland, Colin J
  • Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum. (2010) Gadalla, Nahla B; Elzaki, Salah Eldin; Mukhtar, Ebtihal; Warhurst, David C; El-Sayed, Badria; Sutherland, Colin J
  • Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. (2014) Gadalla, Nahla B; Malmberg, Maja; Adam, Ishag; Oguike, Mary C; Beshir, Khalid; Elzaki, Salah-Eldin; Mukhtar, Izdihar; Gadalla, Amal A; Warhurst, David C; Ngasala, Billy; Mårtensson, Andreas; El-Sayed, Badria B; Gil, J Pedro; Sutherland, Colin J
  • A multiplex allele specific polymerase chain reaction (MAS-PCR) on the dihydrofolate reductase gene for the detection of Cryptosporidium parvum genotypes 1 and 2. (2002) Gile, M; Warhurst, DC; Webster, KA; West, DM; Marshall, JA
  • Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids. (2012) Griffin, Carol E; Hoke, Jonathan M; Samarakoon, Upeka; Duan, Junhui; Mu, Jianbing; Ferdig, Michael T; Warhurst, David C; Cooper, Roland A
  • Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210. (2001) Hankins, EG; Warhurst, DC; Sibley, CH
  • The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. (2015) Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J
  • Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells. (2004) Jayasekera, Samantha; Sissons, James; Tucker, Julie; Rogers, Claire; Nolder, Debbie; Warhurst, David; Alsam, Selwa; White, Jonathan ML; Higgins, EM; Khan, Naveed Ahmed
  • Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone. (2003) Lang'at-Thoruwa, Caroline; Kirby, Geoffrey C; Phillipson, J David; Warhurst, David C; Watt, Robert A; Wright, Colin W
  • Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates. (2005) Maghsood, Amir Hossein; Sissons, James; Rezaian, Mostafa; Nolder, Debbie; Warhurst, David; Khan, Naveed Ahmed
  • Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola. (2009) Menegon, Michela; Pearce, Richard J; Inojosa, Walter O; Pisani, Vincenzo; Abel, Paulo M; Matondo, Alexandre; Bisoffi, Zeno; Majori, Giancarlo; Ord, Rosalynn; Warhurst, David C; Roper, Cally; Severini, Carlo
  • Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V. (2016) Oguike, Mary C; Falade, Catherine O; Shu, Elvis; Enato, Izehiuwa G; Watila, Ismaila; Baba, Ebenezer S; Bruce, Jane; Webster, Jayne; Hamade, Prudence; Meek, Sylvia; Chandramohan, Daniel; Sutherland, Colin J; Warhurst, David; Roper, Cally html
  • Treatment of uncomplicated malaria:[Letter to editor: Authors reply]. (2002) Omar, S; Warhurst, DC
  • Plasmodium falciparum in Kenya: high prevalence of drug-resistance-associated polymorphisms in hospital admissions with severe malaria in an epidemic area. (2001) Omar, SA; Adagu, IS; Gump, DW; Ndaru, NP; Warhurst, DC
  • Can pretreatment screening for dhps and dhfr point mutations in Plasmodium falciparum infections be used to predict sulfadoxine-pyrimethamine treatment failure? (2001) Omar, SA; Adagu, IS; Warhurst, DC
  • Co-trimoxazole compared with sulfadoxine-pyrimethamine in the treatment of uncomplicated malaria in Kenyan children. (2001) Omar, SA; Bakari, A; Owiti, A; Adagu, IS; Warhurst, DC
  • Cryptosporidium prevalence and risk factors among mothers and infants 0 to 6 months in rural and semi-rural Northwest Tanzania: a prospective cohort study. (2014) Pedersen, Sarah H; Wilkinson, Amanda L; Andreasen, Aura; Warhurst, David C; Kinung'hi, Safari M; Urassa, Mark; Mkwashapi, Denna M; Todd, Jim; Changalucha, John; McDermid, Joann M
  • [Presence of the double pfmdr1 mutation 86Tyr and 1246 Tyr in clones of a chloroquine-resistant west African isolate of Plasmodium falciparum]. (2003) Pinheiro, L; Franco, S; Adagu, IS; Rosa, R; Rosário, VE; Warhurst, DC
  • Malaria vectors in the municipality of Serra do Navio, State of Amapá, Amazon Region, Brazil. (2001) Póvoa, M; Wirtz, R; Lacerda, R; Miles, M; Warhurst, D
  • In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates. (2014) Rout, Subhashree; Warhurst, David Charles; Suar, Mrutyunjay; Mahapatra, Rajani Kanta
  • Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. (2007) Siddiqui, Ruqaiyyah; Matin, Abdul; Warhurst, David; Stins, Monique; Khan, Naveed Ahmed
  • TV or not TV? (2002) Smith, A; Portsmouth, S; Curran, B; Warhurst, D; Kell, P; Saulsbury, N
  • Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo. (2006) Stachulski, Andrew V; Berry, Neil G; Lilian Low, AC; Moores, Shelley L; Row, Eleanor; Warhurst, David C; Adagu, Ipemida S; Rossignol, Jean-François
  • Two novel assays for the detection of haemin-binding properties of antimalarials evaluated with compounds isolated from medicinal plants. (2002) Steele, JCP; Phelps, RJ; Simmonds, MSJ; Warhurst, DC; Meyer, DJ
  • Indole and beta-carboline alkaloids from Geissospermum sericeum. (2002) Steele, Jonathan CP; Veitch, Nigel C; Kite, Geoffrey C; Simmonds, Monique SJ; Warhurst, David C
  • Gambian children successfully treated with chloroquine can harbor and transmit Plasmodium falciparum gametocytes carrying resistance genes. (2002) Sutherland, Colin J; Alloueche, Ali; Curtis, Jill; Drakeley, Chris J; Ord, Rosalynn; Duraisingh, Manoj; Greenwood, Brian M; Pinder, Margaret; Warhurst, David; Targett, Geoffrey AT
  • Restricted genetic and antigenic diversity of Plasmodium falciparum under mesoendemic transmission in the Venezuelan Amazon. (2002) Tami, A; Grundmann, H; Sutherland, C; McBride, JS; Cavanagh, DR; Campos, E; Snounou, G; Barnabé, C; Tibayrenc, M; Warhurst, DC
  • New developments: chloroquine-resistance in Plasmodium falciparum. (2001) Warhurst, D
  • A molecular marker for chloroquine-resistant falciparum malaria. (2001) Warhurst, DC
  • Understanding resistance to antimalarial 4-aminoquinolines, cinchona alkaloids and the highly hydrophobic arylaminoalcohols. (2007) Warhurst, DC
  • Advances in mode of action of antimalarials and resistance mechanisms - part 2 of 2. (2013) Warhurst, DC
  • Advances in mode of action of antimalarials and resistance mechanisms - part 1 of 2. (2013) Warhurst, DC
  • Mode of action of artemether lumefantrine (COARTEM): The sole, fixed, oral ADCC and its role in combatting multidrug resistance. (2001) Warhurst, DC; Adagu, IS; Beck, HP; Duraisingh, MT; Kirby, GC; von Seidlein, L; Wright, CW
  • Rational use of drugs against Plasmodium falciparum. (2001) Warhurst, DC; Duraisingh, MT
  • Resistance to antifolates in Plasmodium falciparum, the causative agent of tropical malaria. (2002) Warhurst, David C
  • Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine. (2003) Warhurst, David C
  • Lysosomes and drug resistance in malaria. (2002) Warhurst, David C; Craig, John C; Adagu, Ipemida S
  • Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum. Role of beta-haematin inhibition and drug concentration in vacuolar water- and lipid-phases. (2007) Warhurst, David C; Craig, John C; Adagu, Ipemida S; Guy, R Kiplin; Madrid, Peter B; Fivelman, Quinton L
  • The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids. (2003) Warhurst, David C; Craig, John C; Adagu, Ipemida S; Meyer, David J; Lee, Sylvia Y
  • Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance. (2016) Warhurst, David C; Craig, John C; Raheem, K Saki
  • Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties. (2003) Warhurst, David C; Steele, Jonathan CP; Adagu, Ipemida S; Craig, John C; Cullander, Christopher
  • Granulomatous amoebic encephalitis. (2004) White, JML; Barker, RD; Salisbury, JR; Fife, AJ; Lucas, SB; Warhurst, DC; Higgins, EM
  • Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. (2010) de Souza, J Brian; Okomo, Uduak; Alexander, Neal D; Aziz, Naveed; Owens, Benjamin MJ; Kaur, Harparkash; Jasseh, Momodou; Muangnoicharoen, Sant; Sumariwalla, Percy F; Warhurst, David C; Ward, Stephen A; Conway, David J; Ulloa, Luis; Tracey, Kevin J; Foxwell, Brian MJ; Kaye, Paul M; Walther, Michael
  • Terpenoids from Guarea rhophalocarpa. (2001) del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN
  • Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C
    • Book Section
  • Amebic Infections. (2010) Warhurst, D
  • Malaria: mode of action of drugs and resistance mechanisms. (2010) Warhurst, D
  • Major Tropical Syndromes: The gastrointestinal tract. (2010) Warhurst, DC
  • Potentially Pathogenic Free-living Amoebae. (2009) Warhurst, DC
  • Potentially Pathogenic Free-living Amebae. (2002) Warhurst, DC
  • The parasite. (2001) Warhurst, DC
  • The Parasite. (2008) Warhurst, DC
  • Laboratory Procedures for Diagnosis of Malaria. (2004) Warhurst, DC; Williams, JE
  • Protozoan parasites of the mouse intestinal tract. (2001) Williams, JE; Warhurst, DC
  • Protozoan parasites of the intestinal tract of the cockroach, Periplaneta americana. (2001) Williams, JE; Warhurst, DC
    • Monograph
  • Monitoring antimalarial drug resistance (report of a WHO Consultation). (2001) Bloland, P; D'Alessandro, U; Ringwald, P; Watkins, W (Technical Advisers: Warhurst, D; et al)
    • Conference or Workshop Item
  • The Intra-Host Dynamics of Pfcrt and Pfmdr-1 Alleles Following Antimalarial Treatment in Sudanese Patients. (2008) Gadalla, NB; Adam, I; Warhurst, DC; el-Sayed, BB; Sutherland, CJ
  • Variation in Plasmodium falciparum susceptibility to the cinchona alkaloids is determined by polymorphisms in PfCRT. (2006) Griffin, CE; Warhurst, DC; Cooper, RA
  • Drug-resistance mutations in the dihydropteroate synthetase of Plasmodium falciparum in samples from north-east Tanzania: Society Meeting at Manson House, London, 13 December 2001: Research in progress: short presentation [Poster Presentation]. (2002) Kiani, SA; Curtis, J; Warhurst, DC
  • Back-calculation of the number of inoculated Plasmodium falciparum parasites in a documented case of needlestick malaria in a French nurse. (2003) Tarantola, A; Warhurst, DC; Rachline, A
  • Fatal granulomatous amoebic encephalitis: cutaneous and intracerebral Balamuthia mandrillaris. (2004) White, JML; Barker, RD; Salisbury, JR; Fife, AJ; Lucas, S; Warhurst, DC; Higgins, EM
    • Thesis
  • Standardisation and evaluation of differential diagnostic systems for the detection of Entamoeba histolytica and Entamoeba dispar. (1999) Aguirre-Beltran, Aura Georgina
  • Mechanisms of action of nitazoxanide and related drugs against helminths. (2004) Atherton, Richard Roy Dalzell
  • Drug uptake, sensitivity, interaction studies and resistance associated mutations in Plasmodium falciparum. (2003) Fivelman, QL
  • Drug-susceptibility and molecular characterization of epidemic and endemic malaria in Kenya. (2002) Omar, SA
  • Studies on malaria in Serra do Navioegion, Amapa State, Brazil. (1993) Povoa, Marinete Marins
    • Other
  • Introduction to malaria. (2010) Warhurst, D
  • Malaria (CDROM, 3rd Edition). (2007) Warhurst, D.(acknowledged)