Items where Author is "Baker, David A"

Year Item Type Full Text

Article

Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. (2015) Alam, Mahmood M; Solyakov, Lev; Bottrill, Andrew R; Flueck, Christian; Siddiqui, Faiza A; Singh, Shailja; Mistry, Sharad; Viskaduraki, Maria; Lee, Kate; Hopp, Christine S; Chitnis, Chetan E; Doerig, Christian; Moon, Robert W; Green, Judith L; Holder, Anthony A; Baker, David A; Tobin, Andrew B

Malaria gametocytogenesis. (2010) Baker, David A

Cyclic nucleotide signalling in malaria parasites. (2010) Baker, David A

Adenylyl and guanylyl cyclases from the malaria parasite Plasmodium falciparum. (2004) Baker, David A

Cyclic GMP-dependent protein kinases in protozoa. (2005) Baker, David A; Deng, Wensheng

Cyclic nucleotide signalling in malaria parasites. (2017) Baker, David A; Drought, Laura G; Flueck, Christian; Nofal, Stephanie D; Patel, Avnish; Penzo, Maria; Walker, Eloise M

Purine nucleotide cyclases in the malaria parasite. (2004) Baker, David A; Kelly, John M

Structure, function and evolution of microbial adenylyl and guanylyl cyclases. (2004) Baker, David A; Kelly, John M

Targeting the Malaria Parasite cGMP-Dependent Protein Kinase to Develop New Drugs. (2020) Baker, David A; Matralis, Alexios N; Osborne, Simon A; Large, Jonathan M; Penzo, Maria

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. (2017) Baker, David A; Stewart, Lindsay B; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M; Dessens, Johannes T; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A

Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG. (2021) Balestra, Aurélia C; Koussis, Konstantinos; Klages, Natacha; Howell, Steven A; Flynn, Helen R; Bantscheff, Marcus; Pasquarello, Carla; Perrin, Abigail J; Brusini, Lorenzo; Arboit, Patrizia; Sanz, Olalla; Castaño, Laura Peces-Barba; Withers-Martinez, Chrislaine; Hainard, Alexandre; Ghidelli-Disse, Sonja; Snijders, Ambrosius P; Baker, David A; Blackman, Michael J; Brochet, Mathieu picture_as_pdf

Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development. (2018) Benavente, Ernest Diez; Oresegun, Damilola R; de Sessions, Paola Florez; Walker, Eloise M; Roper, Cally; Dombrowski, Jamille G; de Souza, Rodrigo M; Marinho, Claudio RF; Sutherland, Colin J; Hibberd, Martin L; Mohareb, Fady; Baker, David A; Clark, Taane G; Campino, Susana

Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites. (2014) Brochet, Mathieu; Collins, Mark O; Smith, Terry K; Thompson, Eloise; Sebastian, Sarah; Volkmann, Katrin; Schwach, Frank; Chappell, Lia; Gomes, Ana Rita; Berriman, Matthew; Rayner, Julian C; Baker, David A; Choudhary, Jyoti; Billker, Oliver

Antimalarial activity of primaquine operates via a two-step biochemical relay. (2019) Camarda, Grazia; Jirawatcharadech, Piyaporn; Priestley, Richard S; Saif, Ahmed; March, Sandra; Wong, Michael HL; Leung, Suet; Miller, Alex B; Baker, David A; Alano, Pietro; Paine, Mark JI; Bhatia, Sangeeta N; O'Neill, Paul M; Ward, Stephen A; Biagini, Giancarlo A

Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines. (2016) Campino, Susana; Benavente, Ernest Diez; Assefa, Samuel; Thompson, Eloise; Drought, Laura G; Taylor, Catherine J; Gorvett, Zaria; Carret, Celine K; Flueck, Christian; Ivens, Al C; Kwiatkowski, Dominic P; Alano, Pietro; Baker, David A; Clark, Taane G

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. (2013) Collins, Christine R; Hackett, Fiona; Strath, Malcolm; Penzo, Maria; Withers-Martinez, Chrislaine; Baker, David A; Blackman, Michael J

A novel cyclic GMP-dependent protein kinase is expressed in the ring stage of the Plasmodium falciparum life cycle. (2002) Deng, Wensheng; Baker, David A

The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum. (2003) Deng, Wensheng; Parbhu-Patel, Asha; Meyer, David J; Baker, David A

Signalling in malaria parasites. The MALSIG consortium. (2009) Doerig, C; Baker, D; Billker, O; Blackman, MJ; Chitnis, C; Dhar Kumar, S; Heussler, V; Holder, AA; Kocken, C; Krishna, S; Langsley, G; Lasonder, E; Menard, R; Meissner, M; Pradel, G; Ranford-Cartwright, L; Sharma, A; Sharma, P; Tardieux, T; Tatu, U; Alano, P

A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. (2010) Dvorin, Jeffrey D; Martyn, Derek C; Patel, Saurabh D; Grimley, Joshua S; Collins, Christine R; Hopp, Christine S; Bright, A Taylor; Westenberger, Scott; Winzeler, Elizabeth; Blackman, Michael J; Baker, David A; Wandless, Thomas J; Duraisingh, Manoj T

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. (2019) El Bakkouri, Majida; Kouidmi, Imène; Wernimont, Amy K; Amani, Mehrnaz; Hutchinson, Ashley; Loppnau, Peter; Kim, Jeong Joo; Flueck, Christian; Walker, John R; Seitova, Alma; Senisterra, Guillermo; Kakihara, Yoshito; Kim, Choel; Blackman, Michael J; Calmettes, Charles; Baker, David A; Hui, Raymond

Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites. (2018) Fang, Hanwei; Gomes, Ana Rita; Klages, Natacha; Pino, Paco; Maco, Bohumil; Walker, Eloise M; Zenonos, Zenon A; Angrisano, Fiona; Baum, Jake; Doerig, Christian; Baker, David A; Billker, Oliver; Brochet, Mathieu

Improved synchronous production of Plasmodium falciparum gametocytes in vitro. (2007) Fivelman, Quinton L; McRobert, Louisa; Sharp, Sarah; Taylor, Cathy J; Saeed, Maha; Swales, Claire A; Sutherland, Colin J; Baker, David A

Malaria parasite epigenetics: when virulence and romance collide. (2014) Flueck, Christian; Baker, David A

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion. (2019) Flueck, Christian; Drought, Laura G; Jones, Andrew; Patel, Avnish; Perrin, Abigail J; Walker, Eloise M; Nofal, Stephanie D; Snijders, Ambrosius P; Blackman, Michael J; Baker, David A

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion. (2019) Flueck, Christian; Drought, Laura G; Jones, Andrew; Patel, Avnish; Perrin, Abigail J; Walker, Eloise M; Nofal, Stephanie D; Snijders, Ambrosius P; Blackman, Michael J; Baker, David A

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony. (2017) Ganter, M; Goldberg, JM; Dvorin, JD; Paulo, JA; King, JG; Tripathi, AK; Paul, AS; Yang, J; Coppens, I; Jiang, RH; Elsworth, B; Baker, DA; Dinglasan, RR; Gygi, SP; Duraisingh, MT

Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development. (2015) Green, Judith L; Moon, Robert W; Whalley, David; Bowyer, Paul W; Wallace, Claire; Rochani, Ankit; Nageshan, Rishi K; Howell, Steven A; Grainger, Munira; Jones, Hayley M; Ansell, Keith H; Chapman, Timothy M; Taylor, Debra L; Osborne, Simon A; Baker, David A; Tatu, Utpal; Holder, Anthony A

Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells. (2015) Guenot, Marianne; Loizon, Séverine; Howard, Jennifer; Costa, Giulia; Baker, David A; Mohabeer, Shaneel Y; Troye-Blomberg, Marita; Moreau, Jean-François; Déchanet-Merville, Julie; Mercereau-Puijalon, Odile; Mamani-Matsuda, Maria; Behr, Charlotte

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. (2020) Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. (2020) Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J

The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. (2015) Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J

The role of cGMP signalling in regulating life cycle progression of Plasmodium. (2012) Hopp, Christine S; Bowyer, Paul W; Baker, David A

Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase. (2012) Hopp, Christine S; Flueck, Christian; Solyakov, Lev; Tobin, Andrew; Baker, David A

A transcriptional switch underlies commitment tosexual development in malaria parasites. (2013) Kafsack, BF; Rovira-Graells, N; Clark, TG; Bancells, C; Crowley, VM; Campino, SG; Williams, AE; Drought, LG; Kwiatkowski, DP; Baker, DA; Cortés, A; Llinás, M

A transcriptional switch underlies commitment to sexual development in malaria parasites. (2014) Kafsack, Björn FC; Rovira-Graells, Núria; Clark, Taane G; Bancells, Cristina; Crowley, Valerie M; Campino, Susana G; Williams, April E; Drought, Laura G; Kwiatkowski, Dominic P; Baker, David A; Cortés, Alfred; Llinás, Manuel

Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. (2006) Kelly, John M; McRobert, Louisa; Baker, David A

Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress. (2014) Kim, Jeong Joo; Flueck, Christian; Franz, Eugen; Sanabria-Figueroa, Eduardo; Thompson, Eloise; Lorenz, Robin; Bertinetti, Daniela; Baker, David A; Herberg, Friedrich W; Kim, Choel

Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites. (2024) Koussis, Konstantinos; Haase, Silvia; Withers-Martinez, Chrislaine; Flynn, Helen R; Kunzelmann, Simone; Christodoulou, Evangelos; Ibrahim, Fairouz; Skehel, Mark; Baker, David A; Blackman, Michael J

Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function. (2020) Koussis, Konstantinos; Withers-Martinez, Chrislaine; Baker, David A; Blackman, Michael J

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty. (2019) Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines. (2018) Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A

Targeting Plasmodium falciparum protein kinases with adenosine analogue-oligoarginine conjugates. (2014) Lavogina, Darja; Budu, Alexandre; Enkvist, Erki; Hopp, Christine S; Baker, David A; Langsley, Gordon; Garcia, Celia RS; Uri, Asko

A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum. (2009) Leber, Werner; Skippen, Alison; Fivelman, Quinton L; Bowyer, Paul W; Cockcroft, Shamshad; Baker, David A

Primary structure and sexual stage-specific expression of a LAMMER protein kinase of Plasmodium falciparum. (2001) Li, JL; Targett, GA; Baker, DA

An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi. (2020) Marr, Edward J; Milne, Rachel M; Anar, Burcu; Girling, Gareth; Schwach, Frank; Mooney, Jason P; Nahrendorf, Wiebke; Spence, Philip J; Cunningham, Deirdre; Baker, David A; Langhorne, Jean; Rayner, Julian C; Billker, Oliver; Bushell, Ellen S; Thompson, Joanne

Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites. (2019) Matralis, Alexios N; Malik, Adnan; Penzo, Maria; Moreno, Inmaculada; Almela, Maria J; Camino, Isabel; Crespo, Benigno; Saadeddin, Anas; Ghidelli-Disse, Sonja; Rueda, Lourdes; Calderon, Felix; Osborne, Simon A; Drewes, Gerard; Böesche, Markus; Fernández-Álvaro, Elena; Martin Hernando, Jose Ignacio; Baker, David A

Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. (2008) McRobert, Louisa; Taylor, Cathy J; Deng, Wensheng; Fivelman, Quinton L; Cummings, Ross M; Polley, Spencer D; Billker, Oliver; Baker, David A

Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites. (2017) Meerstein-Kessel, Lisette; van der Lee, Robin; Stone, Will; Lanke, Kjerstin; Baker, David A; Alano, Pietro; Silvestrini, Francesco; Janse, Chris J; Khan, Shahid M; van de Vegte-Bolmer, Marga; Graumans, Wouter; Siebelink-Stoter, Rianne; Kooij, Taco WA; Marti, Matthias; Drakeley, Chris; Campo, Joseph J; van Dam, Teunis JP; Sauerwein, Robert; Bousema, Teun; Huynen, Martijn A

CRISPR-Cas9 Genome Editing of Plasmodium knowlesi. (2020) Mohring, Franziska; Hart, Melissa N; Patel, Avnish; Baker, David A; Moon, Robert W html

A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. (2009) Moon, Robert W; Taylor, Cathy J; Bex, Claudia; Schepers, Rebecca; Goulding, David; Janse, Chris J; Waters, Andrew P; Baker, David A; Billker, Oliver

The gametocyte-activating factor xanthurenic acid stimulates an increase in membrane-associated guanylyl cyclase activity in the human malaria parasite Plasmodium falciparum. (2001) Muhia, DK; Swales, CA; Deng, W; Kelly, JM; Baker, DA

Multiple splice variants encode a novel adenylyl cyclase of possible plastid origin expressed in the sexual stage of the malaria parasite Plasmodium falciparum. (2003) Muhia, David K; Swales, Claire A; Eckstein-Ludwig, Ursula; Saran, Shweta; Polley, Spencer D; Kelly, John M; Schaap, Pauline; Krishna, Sanjeev; Baker, David A

Plasmodium falciparum Guanylyl Cyclase-Alpha and the Activity of Its Appended P4-ATPase Domain Are Essential for cGMP Synthesis and Blood-Stage Egress. (2021) Nofal, Stephanie D; Patel, Avnish; Blackman, Michael J; Flueck, Christian; Baker, David A

Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development. (2024) Patel, Avnish; Fréville, Aline; Rey, Joshua A; Flynn, Helen R; Koussis, Konstantinos; Skehel, Mark J; Blackman, Michael J; Baker, David A

CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation. (2022) Patel, Avnish; Nofal, Stephanie D; Blackman, Michael J; Baker, David A

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. (2019) Patel, Avnish; Perrin, Abigail J; Flynn, Helen R; Bisson, Claudine; Withers-Martinez, Chrislaine; Treeck, Moritz; Flueck, Christian; Nicastro, Giuseppe; Martin, Stephen R; Ramos, Andres; Gilberger, Tim W; Snijders, Ambrosius P; Blackman, Michael J; Baker, David A

High-throughput screening of the Plasmodium falciparum cGMP-dependent protein kinase identified a thiazole scaffold which kills erythrocytic and sexual stage parasites. (2019) Penzo, Maria; de Las Heras-Dueña, Laura; Mata-Cantero, Lydia; Diaz-Hernandez, Beatriz; Vazquez-Muñiz, Maria-Jesus; Ghidelli-Disse, Sonja; Drewes, Gerard; Fernandez-Alvaro, Elena; Baker, David A picture_as_pdf

Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony. (2021) Perrin, Abigail J; Bisson, Claudine; Faull, Peter A; Renshaw, Matthew J; Lees, Rebecca A; Fleck, Roland A; Saibil, Helen R; Snijders, Ambrosius P; Baker, David A; Blackman, Michael J

The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress. (2018) Perrin, Abigail J; Collins, Christine R; Russell, Matthew RG; Collinson, Lucy M; Baker, David A; Blackman, Michael J

cAMP signalling and its role in host cell invasion by malaria parasites. (2020) Perrin, Abigail J; Patel, Avnish; Flueck, Christian; Blackman, Michael J; Baker, David A

Modified Plasmodium falciparum Ring-Stage Survival Assay with ML10 Kinase Inhibitor. (2023) Platon, Lucien; Baker, David A; Ménard, Didier

cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. (2015) Ramdani, Ghania; Naissant, Bernina; Thompson, Eloise; Breil, Florence; Lorthiois, Audrey; Dupuy, Florian; Cummings, Ross; Duffier, Yoann; Corbett, Yolanda; Mercereau-Puijalon, Odile; Vernick, Kenneth; Taramelli, Donatella; Baker, David A; Langsley, Gordon; Lavazec, Catherine

An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated gene. (2019) Ravenhall, Matt; Benavente, Ernest Diez; Sutherland, Colin J; Baker, David A; Campino, Susana; Clark, Taane G

Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites. (2020) Ressurreição, Margarida; Thomas, James A; Nofal, Stephanie D; Flueck, Christian; Moon, Robert W; Baker, David A; van Ooij, Christiaan

Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. (2009) Schnick, Claudia; Polley, Spencer D; Fivelman, Quinton L; Ranford-Cartwright, Lisa C; Wilkinson, Shane R; Brannigan, James A; Wilkinson, Anthony J; Baker, David A

Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes. (2006) Sharp, Sarah; Lavstsen, Thomas; Fivelman, Quinton L; Saeed, Maha; McRobert, Louisa; Templeton, Thomas J; Jensen, Anja TR; Baker, David A; Theander, Thor G; Sutherland, Colin J

Differential IL-18 Dependence of Canonical and Adaptive NK Cells for Antibody Dependent Responses to P. falciparum. (2020) Sherratt, Samuel; Patel, Avnish; Baker, David A; Riley, Eleanor M; Goodier, Martin R

Plasmodium falciparum Sexual Commitment Rate Variation among Clinical Isolates and Diverse Laboratory-Adapted Lines. (2022) Stewart, Lindsay B; Freville, Aline; Voss, Till S; Baker, David A; Awandare, Gordon A; Conway, David J

Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. (2008) Taylor, Cathy J; McRobert, Louisa; Baker, David A

The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony. (2009) Taylor, Helen M; McRobert, Louisa; Grainger, Munira; Sicard, Audrey; Dluzewski, Anton R; Hopp, Christine S; Holder, Anthony A; Baker, David A

Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. (2014) Tewari, Rita; Patzewitz, Eva-Maria; Poulin, Benoit; Stewart, Lindsay; Baker, David A

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG). (2018) Tsagris, Denise J; Birchall, Kristian; Bouloc, Nathalie; Large, Jonathan M; Merritt, Andy; Smiljanic-Hurley, Ela; Wheldon, Mary; Ansell, Keith H; Kettleborough, Catherine; Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A

The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification. (2005) Young, Jason A; Fivelman, Quinton L; Blair, Peter L; de la Vega, Patricia; Le Roch, Karine G; Zhou, Yingyao; Carucci, Daniel J; Baker, David A; Winzeler, Elizabeth A

Conference or Workshop Item

P-falciparum gametogenesis is mediated by cGMPdependent protein kinase. (2008) McRobert, L; Taylor, CJ; Deng, W; Fivelman, Q; Cummings, R; Billker, O; Baker, DA

Plasmodium falciparum cGMP-dependent protein kinase plays a central role in schizogony. (2008) Taylor, HM; McRobert, L; Grainger, M; Holder, AA; Baker, DA

Thesis

Investigations into Phosphodieterases as Targets for Antimalarial Drug Discovery. (2015) Drought, LG

Investigation of the role of GCα in activating cGMP signalling in Plasmodium falciparum and how cyclic nucleotide signalling modulates molecular motor function. (2019) Nofal, SD

Exploring energy metabolism in male and female Plasmodium falciparum gametocytes. (2023) Sparkes, PC

Investigation of the Relationship between CGMP Signalling and Calcium Mobilisation in Plasmodium Falciparum with a Focus on the Role of Phosphodiesterases in Sexual Development. (2018) Walker, EM

Podcast

David Baker - Using Viagra to control malaria. (2015) UNSPECIFIED grid_on

May 2015 - predicting pandemics, the impact of cold weather, and using viagra to control malaria. (2015) UNSPECIFIED grid_on