Items where Author or Contributor is "Fortes Francisco, Amanda"

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Number of items: 43.

2023

Francisco, Amanda F; Chen, Gong; Wang, Wen; Sykes, Melissa L; Escudié, Fanny; Scandale, Ivan; Olmo, Francisco; Shackleford, David M; Zulfiqar, Bilal; Kratz, Jadel M; +7 more... Pham, Thao; Saunders, Jessica; Hu, Meiyu; Avery, Vicky M; Charman, Susan A; Kelly, John M; Chatelain, Eric; (2023) Preclinical data do not support the use of amiodarone or dronedarone as antiparasitic drugs for Chagas disease at the approved human dosing regimen. Frontiers in tropical diseases, 4. DOI: https://doi.org/10.3389/fitd.2023.1254061
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Francisco, Amanda Fortes; Sousa, Giovane R; Vaughan, Mhairi; Langston, Harry; Khan, Archie; Jayawardhana, Shiromani; Taylor, Martin C; Lewis, Michael D; Kelly, John M; (2023) Cardiac Abnormalities in a Predictive Mouse Model of Chagas Disease. Pathogens, 12 (11). p. 1364. DOI: https://doi.org/10.3390/pathogens12111364
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González, Silvia; Wall, Richard J; Thomas, John; Braillard, Stephanie; Brunori, Gino; Camino Díaz, Isabel; Cantizani, Juan; Carvalho, Sandra; Castañeda Casado, Pablo; Chatelain, Eric; +20 more... Cotillo, Ignacio; Fiandor, Jose M; Francisco, Amanda Fortes; Grimsditch, David; Keenan, Martine; Kelly, John M; Kessler, Albane; Luise, Chiara; Lyon, Jon J; MacLean, Lorna; Marco, Maria; Martin, J Julio; Martinez Martinez, Maria S; Paterson, Christy; Read, Kevin D; Santos-Villarejo, Angel; Zuccotto, Fabio; Wyllie, Susan; Miles, Tim J; De Rycker, Manu; (2023) Short-course combination treatment for experimental chronic Chagas disease. Science translational medicine, 15 (726). eadg8105-. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.adg8105
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Racané, Livio; Ptiček, Lucija; Kostrun, Sanja; Raić-Malić, Silvana; Taylor, Martin Craig; Delves, Michael; Alsford, Sam; Olmo, Francisco; Francisco, Amanda Fortes; Kelly, John M; (2023) Bis-6-amidino-benzothiazole Derivative that Cures Experimental Stage 1 African Trypanosomiasis with a Single Dose. Journal of medicinal chemistry, 66 (18). pp. 13043-13057. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.3c01051
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Rao, Srinivasa PS; Gould, Matthew K; Noeske, Jonas; Saldivia, Manuel; Jumani, Rajiv S; Ng, Pearly S; René, Olivier; Chen, Yen-Liang; Kaiser, Marcel; Ritchie, Ryan; +32 more... Francisco, Amanda Fortes; Johnson, Nila; Patra, Debjani; Cheung, Harry; Deniston, Colin; Schenk, Andreas D; Cortopassi, Wilian A; Schmidt, Remo S; Wiedemar, Natalie; Thomas, Bryanna; Palkar, Rima; Ghafar, Nahdiyah A; Manoharan, Vanessa; Luu, Catherine; Gable, Jonathan E; Wan, Kah Fei; Myburgh, Elmarie; Mottram, Jeremy C; Barnes, Whitney; Walker, John; Wartchow, Charles; Aziz, Natasha; Osborne, Colin; Wagner, Juergen; Sarko, Christopher; Kelly, John M; Manjunatha, Ujjini H; Mäser, Pascal; Jiricek, Jan; Lakshminarayana, Suresh B; Barrett, Michael P; Diagana, Thierry T; (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380 (6652). pp. 1349-1356. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.adh0614
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Tawaraishi, Taisuke; Ochida, Atsuko; Akao, Yuichiro; Itono, Sachiko; Kamaura, Masahiro; Akther, Thamina; Shimada, Mitsuyuki; Canan, Stacie; Chowdhury, Sanjoy; Cao, Yafeng; +21 more... Condroski, Kevin; Engkvist, Ola; Francisco, Amanda; Ghosh, Sunil; Kaki, Rina; Kelly, John M; Kimura, Chiaki; Kogej, Thierry; Nagaoka, Kazuya; Naito, Akira; Pairaudeau, Garry; Radu, Constantin; Roberts, Ieuan; Shum, David; Watanabe, Nao-Aki; Xie, Huanxu; Yonezawa, Shuji; Yoshida, Osamu; Yoshida, Ryu; Mowbray, Charles; Perry, Benjamin; (2023) Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection. Journal of medicinal chemistry, 66 (2). pp. 1221-1238. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.2c00775
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2022

Ang, Chee Wei; Lee, Brendon M; Jackson, Colin J; Wang, Yuehong; Franzblau, Scott G; Francisco, Amanda F; Kelly, John M; Bernhardt, Paul V; Tan, Lendl; West, Nicholas P; +6 more... Sykes, Melissa L; Hinton, Alexandra O; Bolisetti, Raghu; Avery, Vicky M; Cooper, Matthew A; Blaskovich, Mark AT; (2022) Nitroimidazopyrazinones with Oral Activity against Tuberculosis and Chagas Disease in Mouse Models of Infection. Journal of Medicinal Chemistry, 65 (19). pp. 13125-13142. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.2c00972
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Francisco, Amanda Fortes; Saade, Ursula; Jayawardhana, Shiromani; Pottel, Hans; Scandale, Ivan; Chatelain, Eric; Liehl, Peter; Kelly, John M; Zrein, Maan; (2022) Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure. PLoS neglected tropical diseases, 16 (10). e0010827. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0010827
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Macleod, Olivia JS; Cook, Alexander D; Webb, Helena; Crow, Mandy; Burns, Roisin; Redpath, Maria; Seisenberger, Stefanie; Trevor, Camilla E; Peacock, Lori; Schwede, Angela; +9 more... Kimblin, Nicola; Francisco, Amanda F; Pepperl, Julia; Rust, Steve; Voorheis, Paul; Gibson, Wendy; Taylor, Martin C; Higgins, Matthew K; Carrington, Mark; (2022) Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor. Nature Communications, 13 (1). 5085-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-022-32728-9
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2021

Scarim, Cauê Benito; Olmo, Francisco; Ferreira, Elizabeth Igne; Chin, Chung Man; Kelly, John M; Fortes Francisco, Amanda; (2021) Image-Based In Vitro Screening Reveals the Trypanostatic Activity of Hydroxymethylnitrofurazone against Trypanosoma cruzi. International Journal of Molecular Sciences, 22 (13). p. 6930. ISSN 1661-6596 DOI: https://doi.org/10.3390/ijms22136930
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2020

Francisco, Amanda F; Jayawardhana, Shiromani; Olmo, Francisco; Lewis, Michael D; Wilkinson, Shane R; Taylor, Martin C; Kelly, John M; (2020) Challenges in Chagas Disease Drug Development. MOLECULES, 25 (12). p. 2799. ISSN 1420-3049 DOI: https://doi.org/10.3390/molecules25122799
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Lewis, Michael D; Paun, Andrea; Romano, Audrey; Langston, Harry; Langner, Charlotte A; Moore, Ian N; Bock, Kevin W; Francisco, Amanda Fortes; Brenchley, Jason M; Sacks, David L; (2020) Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis. PLoS pathogens, 16 (4). e1008456-. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1008456
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Mann, Gurdip Singh; Francisco, Amanda F; Jayawardhana, Shiromani; Taylor, Martin C; Lewis, Michael D; Olmo, Francisco; de Freitas, Elisangela Oliveira; Leoratti, Fabiana MS; López-Camacho, Cesar; Reyes-Sandoval, Arturo; +1 more... Kelly, John M; (2020) Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection. PLoS neglected tropical diseases, 14 (4). e0007717-. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0007717
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Taylor, Martin C; Ward, Alexander I; Olmo, Francisco; Francisco, Amanda F; Jayawardhana, Shiromani; Costa, Fernanda C; Lewis, Michael D; Kelly, John M; (2020) Bioluminescent:Fluorescent Trypanosoma cruzi Reporter Strains as Tools for Exploring Chagas Disease Pathogenesis and Drug Activity. Current pharmaceutical design, 27 (14). pp. 1733-1740. ISSN 1381-6128 DOI: https://doi.org/10.2174/1381612826666201124113214
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Thompson, Andrew M; O'Connor, Patrick D; Marshall, Andrew J; Francisco, Amanda F; Kelly, John M; Riley, Jennifer; Read, Kevin D; Perez, Catherine J; Cornwall, Scott; Thompson, RC Andrew; +8 more... Keenan, Martine; White, Karen L; Charman, Susan A; Zulfiqar, Bilal; Sykes, Melissa L; Avery, Vicky M; Chatelain, Eric; Denny, William A; (2020) Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy. European journal of medicinal chemistry, 207 (112849). 112849-. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2020.112849
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Willcocks, SJ; Cia, F; Francisco, AF; Wren, BW; (2020) Revisiting aminocoumarins for the treatment of melioidosis. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 56 (1). 106002-. ISSN 0924-8579 DOI: https://doi.org/10.1016/j.ijantimicag.2020.106002
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2019

MacGregor, Paula; Gonzalez-Munoz, Andrea L; Jobe, Fatoumatta; Taylor, Martin C; Rust, Steven; Sandercock, Alan M; Macleod, Olivia JS; Van Bocxlaer, Katrien; Francisco, Amanda F; D'Hooge, Francois; +7 more... Tiberghien, Arnaud; Barry, Conor S; Howard, Philip; Higgins, Matthew K; Vaughan, Tristan J; Minter, Ralph; Carrington, Mark; (2019) A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis. PLoS neglected tropical diseases, 13 (5). e0007373-. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0007373
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Teotônio, Isabella Márcia Soares Nogueira; Dias, Nayra; Hagström-Bex, Luciana; Nitz, Nadjar; Francisco, Amanda Fortes; Hecht, Mariana; (2019) Intestinal microbiota - A modulator of the Trypanosoma cruzi-vector-host triad. Microbial pathogenesis, 137. 103711-. ISSN 0882-4010 DOI: https://doi.org/10.1016/j.micpath.2019.103711
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2018

2017

Brand, Stephen; Ko, Eun Jung; Viayna, Elisabet; Thompson, Stephen; Spinks, Daniel; Thomas, Michael; Sandberg, Lars; Francisco, Amanda F; Jayawardhana, Shiromani; Smith, Victoria C; +26 more... Jansen, Chimed; De Rycker, Manu; Thomas, John; MacLean, Lorna; Osuna-Cabello, Maria; Riley, Jennifer; Scullion, Paul; Stojanovski, Laste; Simeons, Frederick RC; Epemolu, Ola; Shishikura, Yoko; Crouch, Sabrinia D; Bakshi, Tania S; Nixon, Christopher J; Reid, Iain H; Hill, Alan P; Underwood, Tim Z; Hindley, Sean J; Robinson, Sharon A; Kelly, John M; Fiandor, Jose M; Wyatt, Paul G; Marco, Maria; Miles, Timothy J; Read, Kevin D; Gilbert, Ian H; (2017) Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi. Journal of medicinal chemistry, 60 (17). pp. 7284-7299. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.7b00463
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2016

Francisco, Amanda Fortes; Jayawardhana, Shiromani; Lewis, Michael D; White, Karen L; Shackleford, David M; Chen, Gong; Saunders, Jessica; Osuna-Cabello, Maria; Read, Kevin D; Charman, Susan A; +2 more... Chatelain, Eric; Kelly, John M; (2016) Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage. Scientific reports, 6 (1). 35351-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep35351
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Kishore, Kranti G; Ghashghaei, Ouldouz; Estarellas, Carolina; Mestre, M Mar; Monturiol, Cristina; Kielland, Nicola; Kelly, John M; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Muñoz-Torrero, Diego; +4 more... Pérez, Belén; Luque, F Javier; Gámez-Montaño, Rocío; Lavilla, Rodolfo; (2016) Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie, 55 (31). pp. 8994-8998. ISSN 0044-8249 DOI: https://doi.org/10.1002/anie.201604109
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Kishore, Kranti G; Ghashghaei, Ouldouz; Estarellas, Carolina; Mestre, M Mar; Monturiol, Cristina; Kielland, Nicola; Kelly, John M; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Muñoz-Torrero, Diego; +4 more... Pérez, Belén; Luque, F Javier; Gámez-Montaño, Rocío; Lavilla, Rodolfo; (2016) Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie (International ed in English), 55 (31). pp. 8994-8998. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.201604109
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2015

2014

2012

Vieira, Paula Melo de Abreu; Francisco, Amanda Fortes; Machado, Evandro Marques de Meneses; Nogueira, Nívia Carolina; Fonseca, Kátia da Silva; Reis, Alexandre Barbosa; Teixeira-Carvalho, Andrea; Martins-Filho, Olindo Assis; Tafuri, Washington Luiz; Carneiro, Cláudia Martins; (2012) Different infective forms trigger distinct immune response in experimental Chagas disease. PloS one, 7 (3). e32912-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0032912
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2011

Arantes, Jerusa Marilda; Francisco, Amanda Fortes; de Abreu Vieira, Paula Melo; Silva, Maisa; Araújo, Márcio Sobreira Silva; de Carvalho, Andréa Teixeira; Pedrosa, Maria Lúcia; Carneiro, Cláudia Martins; Tafuri, Washington Luiz; Martins-Filho, Olindo Assis; +1 more... Elói-Santos, Silvana Maria; (2011) Trypanosoma cruzi: desferrioxamine decreases mortality and parasitemia in infected mice through a trypanostatic effect. EXPERIMENTAL PARASITOLOGY, 128 (4). pp. 401-408. ISSN 0014-4894 DOI: https://doi.org/10.1016/j.exppara.2011.05.011
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2010

Francisco, Amanda Fortes; de Abreu Vieira, Paula Melo; Arantes, Jerusa Marilda; Silva, Maisa; Pedrosa, Maria Lúcia; Elói-Santos, Silvana Maria; Martins-Filho, Olindo Assis; Teixeira-Carvalho, Andréa; Araújo, Márcio Sobreira Silva; Tafuri, Washington Luiz; +1 more... Carneiro, Cláudia Martins; (2010) Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease. Redox report, 15 (4). pp. 185-190. ISSN 1351-0002 DOI: https://doi.org/10.1179/174329210X12650506623528
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Rodrigues, Claudiney Melquíades; Valadares, Helder Magno Silva; Francisco, Amanda Fortes; Arantes, Jerusa Marilda; Campos, Camila França; Teixeira-Carvalho, Andréa; Martins-Filho, Olindo Assis; Araujo, Márcio Sobreira Silva; Arantes, Rosa Maria Esteves; Chiari, Egler; +5 more... Franco, Glória Regina; Machado, Carlos Renato; Pena, Sérgio Danilo Junho; Faria, Ana Maria Caetano; Macedo, Andréa Mara; (2010) Coinfection with different Trypanosoma cruzi strains interferes with the host immune response to infection. PLoS neglected tropical diseases, 4 (10). e846-. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0000846
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2009

Vieira, Paula Melo de Abreu; Francisco, Amanda Fortes; de Souza, Sheler Martins; Malaquias, Luiz Cosme Cotta; Reis, Alexandre Barbosa; Giunchetti, Rodolfo Cordeiro; Veloso, Vanja Maria; de Lana, Marta; Tafuri, Washington Luiz; Carneiro, Cláudia Martins; (2009) Trypanosoma cruzi: Serum levels of nitric oxide and expression of inducible nitric oxide synthase in myocardium and spleen of dogs in the acute stage of infection with metacyclic or blood trypomastigotes. Experimental parasitology, 121 (1). pp. 76-82. ISSN 0014-4894 DOI: https://doi.org/10.1016/j.exppara.2008.09.023
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This list was generated on Mon Mar 18 06:51:24 2024 GMT.