Items where Author or Contributor is "Fortes Francisco, Amanda"
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Number of items: 47.
2024
Khan, Archie A;
Langston, Harry C;
Walsh, Louis;
Roscoe, Rebecca;
Jayawardhana, Shiromani;
Francisco, Amanda Fortes;
Taylor, Martin C;
McCann, Conor J;
Kelly, John M;
Lewis, Michael D;
(2024)
Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy.
Nature Communications, 15 (1).
4400-.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-024-48749-5
Langston, Harry;
Fortes Francisco, Amanda;
Doidge, Ciaran;
Roberts, Chrissy H;
Khan, Archie A;
Jayawardhana, Shiromani;
Taylor, Martin C;
Kelly, John M;
Lewis, Michael D;
(2024)
Dynamics of Trypanosoma cruzi infection in hamsters and novel association with progressive motor dysfunction.
PLoS neglected tropical diseases, 18 (6).
e0012278-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0012278
Olmo, Francisco;
Jayawardhana, Shiromani;
Khan, Archie A;
Langston, Harry C;
Francisco, Amanda Fortes;
Atherton, Richard L;
Ward, Alex I;
Taylor, Martin C;
Kelly, John M;
Lewis, Michael D;
(2024)
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research.
PLoS Neglected Tropical Diseases, 18 (5).
e0012106-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0012106
Trometer, Nathan;
Pecourneau, Jérémy;
Feng, Liwen;
Navarro-Huerta, José A;
Lazarin-Bidóia, Danielle;
de Oliveira Silva Lautenschlager, Sueli;
Maes, Louis;
Fortes Francisco, Amanda;
Kelly, John M;
Meunier, Brigitte;
+4 more...
Cal, Monica;
Mäser, Pascal;
Kaiser, Marcel;
Davioud-Charvet, Elisabeth;
(2024)
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging.
ACS Infectious Diseases, 10 (5).
pp. 1808-1838.
ISSN 2373-8227
DOI: https://doi.org/10.1021/acsinfecdis.4c00137
2023
Francisco, Amanda F;
Chen, Gong;
Wang, Wen;
Sykes, Melissa L;
Escudié, Fanny;
Scandale, Ivan;
Olmo, Francisco;
Shackleford, David M;
Zulfiqar, Bilal;
Kratz, Jadel M;
+7 more...
Pham, Thao;
Saunders, Jessica;
Hu, Meiyu;
Avery, Vicky M;
Charman, Susan A;
Kelly, John M;
Chatelain, Eric;
(2023)
Preclinical data do not support the use of amiodarone or dronedarone as antiparasitic drugs for Chagas disease at the approved human dosing regimen.
Frontiers in tropical diseases, 4.
DOI: https://doi.org/10.3389/fitd.2023.1254061
Francisco, Amanda Fortes;
Sousa, Giovane R;
Vaughan, Mhairi;
Langston, Harry;
Khan, Archie;
Jayawardhana, Shiromani;
Taylor, Martin C;
Lewis, Michael D;
Kelly, John M;
(2023)
Cardiac Abnormalities in a Predictive Mouse Model of Chagas Disease.
Pathogens, 12 (11).
p. 1364.
DOI: https://doi.org/10.3390/pathogens12111364
González, Silvia;
Wall, Richard J;
Thomas, John;
Braillard, Stephanie;
Brunori, Gino;
Camino Díaz, Isabel;
Cantizani, Juan;
Carvalho, Sandra;
Castañeda Casado, Pablo;
Chatelain, Eric;
+20 more...
Cotillo, Ignacio;
Fiandor, Jose M;
Francisco, Amanda Fortes;
Grimsditch, David;
Keenan, Martine;
Kelly, John M;
Kessler, Albane;
Luise, Chiara;
Lyon, Jon J;
MacLean, Lorna;
Marco, Maria;
Martin, J Julio;
Martinez Martinez, Maria S;
Paterson, Christy;
Read, Kevin D;
Santos-Villarejo, Angel;
Zuccotto, Fabio;
Wyllie, Susan;
Miles, Tim J;
De Rycker, Manu;
(2023)
Short-course combination treatment for experimental chronic Chagas disease.
Science translational medicine, 15 (726).
eadg8105-.
ISSN 1946-6234
DOI: https://doi.org/10.1126/scitranslmed.adg8105
Jayawardhana, Shiromani;
Ward, Alexander I;
Francisco, Amanda F;
Lewis, Michael D;
Taylor, Martin C;
Kelly, John M;
Olmo, Francisco;
(2023)
Benznidazole treatment leads to DNA damage in Trypanosoma cruzi and the persistence of rare widely dispersed non-replicative amastigotes in mice.
PLoS Pathogens, 19 (11).
e1011627-.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1011627
Racané, Livio;
Ptiček, Lucija;
Kostrun, Sanja;
Raić-Malić, Silvana;
Taylor, Martin Craig;
Delves, Michael;
Alsford, Sam;
Olmo, Francisco;
Francisco, Amanda Fortes;
Kelly, John M;
(2023)
Bis-6-amidino-benzothiazole Derivative that Cures Experimental Stage 1 African Trypanosomiasis with a Single Dose.
Journal of medicinal chemistry, 66 (18).
pp. 13043-13057.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.3c01051
Rao, Srinivasa PS;
Gould, Matthew K;
Noeske, Jonas;
Saldivia, Manuel;
Jumani, Rajiv S;
Ng, Pearly S;
René, Olivier;
Chen, Yen-Liang;
Kaiser, Marcel;
Ritchie, Ryan;
+32 more...
Francisco, Amanda Fortes;
Johnson, Nila;
Patra, Debjani;
Cheung, Harry;
Deniston, Colin;
Schenk, Andreas D;
Cortopassi, Wilian A;
Schmidt, Remo S;
Wiedemar, Natalie;
Thomas, Bryanna;
Palkar, Rima;
Ghafar, Nahdiyah A;
Manoharan, Vanessa;
Luu, Catherine;
Gable, Jonathan E;
Wan, Kah Fei;
Myburgh, Elmarie;
Mottram, Jeremy C;
Barnes, Whitney;
Walker, John;
Wartchow, Charles;
Aziz, Natasha;
Osborne, Colin;
Wagner, Juergen;
Sarko, Christopher;
Kelly, John M;
Manjunatha, Ujjini H;
Mäser, Pascal;
Jiricek, Jan;
Lakshminarayana, Suresh B;
Barrett, Michael P;
Diagana, Thierry T;
(2023)
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Science, 380 (6652).
pp. 1349-1356.
ISSN 0036-8075
DOI: https://doi.org/10.1126/science.adh0614
Tawaraishi, Taisuke;
Ochida, Atsuko;
Akao, Yuichiro;
Itono, Sachiko;
Kamaura, Masahiro;
Akther, Thamina;
Shimada, Mitsuyuki;
Canan, Stacie;
Chowdhury, Sanjoy;
Cao, Yafeng;
+21 more...
Condroski, Kevin;
Engkvist, Ola;
Francisco, Amanda;
Ghosh, Sunil;
Kaki, Rina;
Kelly, John M;
Kimura, Chiaki;
Kogej, Thierry;
Nagaoka, Kazuya;
Naito, Akira;
Pairaudeau, Garry;
Radu, Constantin;
Roberts, Ieuan;
Shum, David;
Watanabe, Nao-Aki;
Xie, Huanxu;
Yonezawa, Shuji;
Yoshida, Osamu;
Yoshida, Ryu;
Mowbray, Charles;
Perry, Benjamin;
(2023)
Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection.
Journal of medicinal chemistry, 66 (2).
pp. 1221-1238.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.2c00775
2022
Ang, Chee Wei;
Lee, Brendon M;
Jackson, Colin J;
Wang, Yuehong;
Franzblau, Scott G;
Francisco, Amanda F;
Kelly, John M;
Bernhardt, Paul V;
Tan, Lendl;
West, Nicholas P;
+6 more...
Sykes, Melissa L;
Hinton, Alexandra O;
Bolisetti, Raghu;
Avery, Vicky M;
Cooper, Matthew A;
Blaskovich, Mark AT;
(2022)
Nitroimidazopyrazinones with Oral Activity against Tuberculosis and Chagas Disease in Mouse Models of Infection.
Journal of Medicinal Chemistry, 65 (19).
pp. 13125-13142.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.2c00972
Francisco, Amanda Fortes;
Saade, Ursula;
Jayawardhana, Shiromani;
Pottel, Hans;
Scandale, Ivan;
Chatelain, Eric;
Liehl, Peter;
Kelly, John M;
Zrein, Maan;
(2022)
Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure.
PLoS neglected tropical diseases, 16 (10).
e0010827-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0010827
Macleod, Olivia JS;
Cook, Alexander D;
Webb, Helena;
Crow, Mandy;
Burns, Roisin;
Redpath, Maria;
Seisenberger, Stefanie;
Trevor, Camilla E;
Peacock, Lori;
Schwede, Angela;
+9 more...
Kimblin, Nicola;
Francisco, Amanda F;
Pepperl, Julia;
Rust, Steve;
Voorheis, Paul;
Gibson, Wendy;
Taylor, Martin C;
Higgins, Matthew K;
Carrington, Mark;
(2022)
Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor.
Nature Communications, 13 (1).
5085-.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-022-32728-9
2021
Scarim, Cauê Benito;
Olmo, Francisco;
Ferreira, Elizabeth Igne;
Chin, Chung Man;
Kelly, John M;
Fortes Francisco, Amanda;
(2021)
Image-Based In Vitro Screening Reveals the Trypanostatic Activity of Hydroxymethylnitrofurazone against Trypanosoma cruzi.
International Journal of Molecular Sciences, 22 (13).
p. 6930.
ISSN 1661-6596
DOI: https://doi.org/10.3390/ijms22136930
2020
Francisco, Amanda F;
Jayawardhana, Shiromani;
Olmo, Francisco;
Lewis, Michael D;
Wilkinson, Shane R;
Taylor, Martin C;
Kelly, John M;
(2020)
Challenges in Chagas Disease Drug Development.
MOLECULES, 25 (12).
p. 2799.
ISSN 1420-3049
DOI: https://doi.org/10.3390/molecules25122799
Lewis, Michael D;
Paun, Andrea;
Romano, Audrey;
Langston, Harry;
Langner, Charlotte A;
Moore, Ian N;
Bock, Kevin W;
Francisco, Amanda Fortes;
Brenchley, Jason M;
Sacks, David L;
(2020)
Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis.
PLoS pathogens, 16 (4).
e1008456-.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1008456
Mann, Gurdip Singh;
Francisco, Amanda F;
Jayawardhana, Shiromani;
Taylor, Martin C;
Lewis, Michael D;
Olmo, Francisco;
de Freitas, Elisangela Oliveira;
Leoratti, Fabiana MS;
López-Camacho, Cesar;
Reyes-Sandoval, Arturo;
+1 more...
Kelly, John M;
(2020)
Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection.
PLoS neglected tropical diseases, 14 (4).
e0007717-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0007717
Taylor, Martin C;
Ward, Alexander I;
Olmo, Francisco;
Francisco, Amanda F;
Jayawardhana, Shiromani;
Costa, Fernanda C;
Lewis, Michael D;
Kelly, John M;
(2020)
Bioluminescent:Fluorescent Trypanosoma cruzi Reporter Strains as Tools for Exploring Chagas Disease Pathogenesis and Drug Activity.
Current pharmaceutical design, 27 (14).
pp. 1733-1740.
ISSN 1381-6128
DOI: https://doi.org/10.2174/1381612826666201124113214
Taylor, Martin C;
Ward, Alexander;
Olmo, Francisco;
Jayawardhana, Shiromani;
Francisco, Amanda F;
Lewis, Michael D;
Kelly, John M;
(2020)
Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection.
PLoS neglected tropical diseases, 14 (3).
e0008007-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0008007
Thompson, Andrew M;
O'Connor, Patrick D;
Marshall, Andrew J;
Francisco, Amanda F;
Kelly, John M;
Riley, Jennifer;
Read, Kevin D;
Perez, Catherine J;
Cornwall, Scott;
Thompson, RC Andrew;
+8 more...
Keenan, Martine;
White, Karen L;
Charman, Susan A;
Zulfiqar, Bilal;
Sykes, Melissa L;
Avery, Vicky M;
Chatelain, Eric;
Denny, William A;
(2020)
Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy.
European journal of medicinal chemistry, 207 (112849).
112849-.
ISSN 0223-5234
DOI: https://doi.org/10.1016/j.ejmech.2020.112849
Ward, Alexander I;
Lewis, Michael D;
Khan, Archie A;
McCann, Conor J;
Francisco, Amanda F;
Jayawardhana, Shiromani;
Taylor, Martin C;
Kelly, John M;
(2020)
In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution.
mBio, 11 (4).
pp. 1-13.
ISSN 2150-7511
DOI: https://doi.org/10.1128/mBio.01242-20
Willcocks, SJ;
Cia, F;
Francisco, AF;
Wren, BW;
(2020)
Revisiting aminocoumarins for the treatment of melioidosis.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 56 (1).
106002-.
ISSN 0924-8579
DOI: https://doi.org/10.1016/j.ijantimicag.2020.106002
2019
MacGregor, Paula;
Gonzalez-Munoz, Andrea L;
Jobe, Fatoumatta;
Taylor, Martin C;
Rust, Steven;
Sandercock, Alan M;
Macleod, Olivia JS;
Van Bocxlaer, Katrien;
Francisco, Amanda F;
D'Hooge, Francois;
+7 more...
Tiberghien, Arnaud;
Barry, Conor S;
Howard, Philip;
Higgins, Matthew K;
Vaughan, Tristan J;
Minter, Ralph;
Carrington, Mark;
(2019)
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
PLoS neglected tropical diseases, 13 (5).
e0007373-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0007373
Taylor, Martin C;
Francisco, Amanda F;
Jayawardhana, Shiromani;
Mann, Gurdip Singh;
Ward, Alexander I;
Olmo, Francisco;
Lewis, Michael D;
Kelly, John M;
(2019)
Exploiting Genetically Modified Dual-Reporter Strains to Monitor Experimental Trypanosoma cruzi Infections and Host-Parasite Interactions.
Springer New York, pp. 147-163.
ISBN 9781493991471
DOI: https://doi.org/10.1007/978-1-4939-9148-8_11
Teotônio, Isabella Márcia Soares Nogueira;
Dias, Nayra;
Hagström-Bex, Luciana;
Nitz, Nadjar;
Francisco, Amanda Fortes;
Hecht, Mariana;
(2019)
Intestinal microbiota - A modulator of the Trypanosoma cruzi-vector-host triad.
Microbial pathogenesis, 137.
103711-.
ISSN 0882-4010
DOI: https://doi.org/10.1016/j.micpath.2019.103711
2018
Costa, Fernanda Cristina;
Francisco, Amanda Fortes;
Jayawardhana, Shiromani;
Calderano, Simone Guedes;
Lewis, Michael D;
Olmo, Francisco;
Beneke, Tom;
Gluenz, Eva;
Sunter, Jack;
Dean, Samuel;
+2 more...
Kelly, John Morrison;
Taylor, Martin Craig;
(2018)
Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.
PLoS neglected tropical diseases, 12 (4).
e0006388-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0006388
Francisco, Amanda Fortes;
Jayawardhana, Shiromani;
Taylor, Martin C;
Lewis, Michael D;
Kelly, John M;
(2018)
Assessing the Effectiveness of Curative Benznidazole Treatment in Preventing Chronic Cardiac Pathology in Experimental Models of Chagas Disease.
Antimicrobial agents and chemotherapy, 62 (10).
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00832-18
Lewis, Michael D;
Francisco, Amanda F;
Jayawardhana, Shiromani;
Langston, Harry;
Taylor, Martin C;
Kelly, John M;
(2018)
Imaging the development of chronic Chagas disease after oral transmission.
Scientific reports, 8 (1).
11292-.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-018-29564-7
Wijnant, Gert-Jan;
Van Bocxlaer, Katrien;
Fortes Francisco, Amanda;
Yardley, Vanessa;
Harris, Andy;
Alavijeh, Mo;
Murdan, Sudaxshina;
Croft, Simon L;
(2018)
Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B.
Antimicrobial agents and chemotherapy, 62 (10).
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00631-18
2017
Brand, Stephen;
Ko, Eun Jung;
Viayna, Elisabet;
Thompson, Stephen;
Spinks, Daniel;
Thomas, Michael;
Sandberg, Lars;
Francisco, Amanda F;
Jayawardhana, Shiromani;
Smith, Victoria C;
+26 more...
Jansen, Chimed;
De Rycker, Manu;
Thomas, John;
MacLean, Lorna;
Osuna-Cabello, Maria;
Riley, Jennifer;
Scullion, Paul;
Stojanovski, Laste;
Simeons, Frederick RC;
Epemolu, Ola;
Shishikura, Yoko;
Crouch, Sabrinia D;
Bakshi, Tania S;
Nixon, Christopher J;
Reid, Iain H;
Hill, Alan P;
Underwood, Tim Z;
Hindley, Sean J;
Robinson, Sharon A;
Kelly, John M;
Fiandor, Jose M;
Wyatt, Paul G;
Marco, Maria;
Miles, Timothy J;
Read, Kevin D;
Gilbert, Ian H;
(2017)
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
Journal of medicinal chemistry, 60 (17).
pp. 7284-7299.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00463
Campos, Mônica C;
Phelan, Jody;
Francisco, Amanda F;
Taylor, Martin C;
Lewis, Michael D;
Pain, Arnab;
Clark, Taane G;
Kelly, John M;
(2017)
Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole.
Scientific reports, 7 (1).
14407-.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-017-14986-6
Francisco, Amanda F;
Jayawardhana, Shiromani;
Lewis, Michael D;
Taylor, Martin C;
Kelly, John M;
(2017)
Biological factors that impinge on Chagas disease drug development.
Parasitology, 144 (14).
pp. 1871-1880.
ISSN 0031-1820
DOI: https://doi.org/10.1017/S0031182017001469
2016
Francisco, Amanda Fortes;
Jayawardhana, Shiromani;
Lewis, Michael D;
White, Karen L;
Shackleford, David M;
Chen, Gong;
Saunders, Jessica;
Osuna-Cabello, Maria;
Read, Kevin D;
Charman, Susan A;
+2 more...
Chatelain, Eric;
Kelly, John M;
(2016)
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage.
Scientific reports, 6 (1).
35351-.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep35351
Kishore, Kranti G;
Ghashghaei, Ouldouz;
Estarellas, Carolina;
Mestre, M Mar;
Monturiol, Cristina;
Kielland, Nicola;
Kelly, John M;
Francisco, Amanda Fortes;
Jayawardhana, Shiromani;
Muñoz-Torrero, Diego;
+4 more...
Pérez, Belén;
Luque, F Javier;
Gámez-Montaño, Rocío;
Lavilla, Rodolfo;
(2016)
Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
Angewandte Chemie, 55 (31).
pp. 8994-8998.
ISSN 0044-8249
DOI: https://doi.org/10.1002/anie.201604109
Kishore, Kranti G;
Ghashghaei, Ouldouz;
Estarellas, Carolina;
Mestre, M Mar;
Monturiol, Cristina;
Kielland, Nicola;
Kelly, John M;
Francisco, Amanda Fortes;
Jayawardhana, Shiromani;
Muñoz-Torrero, Diego;
+4 more...
Pérez, Belén;
Luque, F Javier;
Gámez-Montaño, Rocío;
Lavilla, Rodolfo;
(2016)
Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
Angewandte Chemie (International ed in English), 55 (31).
pp. 8994-8998.
ISSN 1433-7851
DOI: https://doi.org/10.1002/anie.201604109
Lewis, Michael D;
Francisco, Amanda Fortes;
Taylor, Martin C;
Jayawardhana, Shiromani;
Kelly, John M;
(2016)
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.
Cellular microbiology, 18 (10).
pp. 1429-1443.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12584
2015
Francisco, Amanda Fortes;
Lewis, Michael D;
Jayawardhana, Shiromani;
Taylor, Martin C;
Chatelain, Eric;
Kelly, John M;
(2015)
Reply to "Drug Susceptibility of Genetically Engineered Trypanosoma cruzi Strains and Sterile Cure in Animal Models as a Criterion for Potential Clinical Efficacy of Anti-T. cruzi Drugs".
Antimicrobial agents and chemotherapy, 59 (12).
7925-.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.02022-15
Francisco, Amanda Fortes;
Lewis, Michael D;
Jayawardhana, Shiromani;
Taylor, Martin C;
Chatelain, Eric;
Kelly, John M;
(2015)
Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging.
Antimicrobial agents and chemotherapy, 59 (8).
pp. 4653-4661.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00520-15
Taylor, Martin C;
Lewis, Michael D;
Fortes Francisco, Amanda;
Wilkinson, Shane R;
Kelly, John M;
(2015)
The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence.
PLoS neglected tropical diseases, 9 (4).
e0003707-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0003707
2014
Lewis, Michael D;
Fortes Francisco, Amanda;
Taylor, Martin C;
Burrell-Saward, Hollie;
McLatchie, Alex P;
Miles, Michael A;
Kelly, John M;
(2014)
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection.
Cellular microbiology, 16 (9).
pp. 1285-1300.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12297
Lewis, Michael D;
Francisco, Amanda Fortes;
Taylor, Martin C;
Kelly, John M;
(2014)
A new experimental model for assessing drug efficacy against Trypanosoma cruzi infection based on highly sensitive in vivo imaging.
Journal of biomolecular screening, 20 (1).
pp. 36-43.
ISSN 1087-0571
DOI: https://doi.org/10.1177/1087057114552623
2012
Vieira, Paula Melo de Abreu;
Francisco, Amanda Fortes;
Machado, Evandro Marques de Meneses;
Nogueira, Nívia Carolina;
Fonseca, Kátia da Silva;
Reis, Alexandre Barbosa;
Teixeira-Carvalho, Andrea;
Martins-Filho, Olindo Assis;
Tafuri, Washington Luiz;
Carneiro, Cláudia Martins;
(2012)
Different infective forms trigger distinct immune response in experimental Chagas disease.
PloS one, 7 (3).
e32912-.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0032912
2011
Arantes, Jerusa Marilda;
Francisco, Amanda Fortes;
de Abreu Vieira, Paula Melo;
Silva, Maisa;
Araújo, Márcio Sobreira Silva;
de Carvalho, Andréa Teixeira;
Pedrosa, Maria Lúcia;
Carneiro, Cláudia Martins;
Tafuri, Washington Luiz;
Martins-Filho, Olindo Assis;
+1 more...
Elói-Santos, Silvana Maria;
(2011)
Trypanosoma cruzi: desferrioxamine decreases mortality and parasitemia in infected mice through a trypanostatic effect.
EXPERIMENTAL PARASITOLOGY, 128 (4).
pp. 401-408.
ISSN 0014-4894
DOI: https://doi.org/10.1016/j.exppara.2011.05.011
2010
Francisco, Amanda Fortes;
de Abreu Vieira, Paula Melo;
Arantes, Jerusa Marilda;
Silva, Maisa;
Pedrosa, Maria Lúcia;
Elói-Santos, Silvana Maria;
Martins-Filho, Olindo Assis;
Teixeira-Carvalho, Andréa;
Araújo, Márcio Sobreira Silva;
Tafuri, Washington Luiz;
+1 more...
Carneiro, Cláudia Martins;
(2010)
Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease.
Redox report, 15 (4).
pp. 185-190.
ISSN 1351-0002
DOI: https://doi.org/10.1179/174329210X12650506623528
Rodrigues, Claudiney Melquíades;
Valadares, Helder Magno Silva;
Francisco, Amanda Fortes;
Arantes, Jerusa Marilda;
Campos, Camila França;
Teixeira-Carvalho, Andréa;
Martins-Filho, Olindo Assis;
Araujo, Márcio Sobreira Silva;
Arantes, Rosa Maria Esteves;
Chiari, Egler;
+5 more...
Franco, Glória Regina;
Machado, Carlos Renato;
Pena, Sérgio Danilo Junho;
Faria, Ana Maria Caetano;
Macedo, Andréa Mara;
(2010)
Coinfection with different Trypanosoma cruzi strains interferes with the host immune response to infection.
PLoS neglected tropical diseases, 4 (10).
e846-.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0000846
2009
Vieira, Paula Melo de Abreu;
Francisco, Amanda Fortes;
de Souza, Sheler Martins;
Malaquias, Luiz Cosme Cotta;
Reis, Alexandre Barbosa;
Giunchetti, Rodolfo Cordeiro;
Veloso, Vanja Maria;
de Lana, Marta;
Tafuri, Washington Luiz;
Carneiro, Cláudia Martins;
(2009)
Trypanosoma cruzi: Serum levels of nitric oxide and expression of inducible nitric oxide synthase in myocardium and spleen of dogs in the acute stage of infection with metacyclic or blood trypomastigotes.
Experimental parasitology, 121 (1).
pp. 76-82.
ISSN 0014-4894
DOI: https://doi.org/10.1016/j.exppara.2008.09.023