Croft, Simon L; Seifert, Karin; Duchêne, Michael; (2003) Antiprotozoal activities of phospholipid analogues. Molecular and biochemical parasitology, 126 (2). pp. 165-172. ISSN 0166-6851 DOI: https://doi.org/10.1016/s0166-6851(02)00283-9 Full text not available from this repository.

Das, Shantanabha; Freier, Anja; Boussoffara, Thouraya; Das, Sushmita; Oswald, Detlef; Losch, Florian O; Selka, Melanie; Sacerdoti-Sierra, Nina; Schönian, Gabriele; Wiesmüller, Karl-Heinz; +10 more... Seifert, Karin; Schroff, Matthias; Juhls, Christiane; Jaffe, Charles L; Roy, Syamal; Das, Pradeep; Louzir, Hechmi; Croft, Simon L; Modabber, Farrokh; Walden, Peter; (2014) Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. Science translational medicine, 6 (234). 234ra56-. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.3008222 Full text not available from this repository.

Mohamed-Ahmed, Abeer HA; Les, Karolina A; Seifert, Karin; Croft, Simon L; Brocchini, Stephen; (2013) Noncovalent complexation of amphotericin-B with Poly(α-glutamic acid). Molecular pharmaceutics, 10 (3). pp. 940-950. ISSN 1543-8384 DOI: https://doi.org/10.1021/mp300339p Full text not available from this repository.

Mohamed-Ahmed, Abeer HA; Seifert, Karin; Yardley, Vanessa; Burrell-Saward, Hollie; Brocchini, Stephen; Croft, Simon L; (2013) Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex. Antimicrobial agents and chemotherapy, 57 (10). pp. 4608-4614. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02343-12 Full text not available from this repository.

Pérez-Victoria, F Javier; Sánchez-Cañete, María P; Seifert, Karin; Croft, Simon L; Sundar, Shyam; Castanys, Santiago; Gamarro, Francisco; (2006) Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. Drug resistance updates, 9 (1-2). pp. 26-39. ISSN 1368-7646 DOI: https://doi.org/10.1016/j.drup.2006.04.001 Full text not available from this repository.

Seifert, K; Duchêne, M; Wernsdorfer, WH; Kollaritsch, H; Scheiner, O; Wiedermann, G; Hottkowitz, T; Eibl, H; (2001) Effects of miltefosine and other alkylphosphocholines on human intestinal parasite Entamoeba histolytica. Antimicrobial agents and chemotherapy, 45 (5). pp. 1505-1510. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.45.5.1505-1510.2001 Full text not available from this repository.

Seifert, Karin; Croft, Simon L; (2006) In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. Antimicrobial agents and chemotherapy, 50 (1). pp. 73-79. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.50.1.73-79.2006 Full text not available from this repository.

Seifert, Karin; Escobar, Patricia; Croft, Simon L; (2010) In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. The Journal of antimicrobial chemotherapy, 65 (3). pp. 508-511. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkp500 Full text not available from this repository.

Seifert, Karin; Juhls, Christiane; Salguero, Francisco J; Croft, Simon L; (2015) Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. Antimicrobial agents and chemotherapy, 59 (9). pp. 5819-5823. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00273-15 Full text not available from this repository.

Seifert, Karin; Lemke, Andreas; Croft, Simon L; Kayser, Oliver; (2007) Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives. Antimicrobial agents and chemotherapy, 51 (12). pp. 4525-4528. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00465-07 Full text not available from this repository.

Seifert, Karin; Matu, Sangeeta; Javier Pérez-Victoria, F; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L; (2003) Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). International journal of antimicrobial agents, 22 (4). pp. 380-387. ISSN 0924-8579 DOI: https://doi.org/10.1016/s0924-8579(03)00125-0 Full text not available from this repository.

Seifert, Karin; Munday, Jane; Syeda, Tahmina; Croft, Simon L; (2011) In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. The Journal of antimicrobial chemotherapy, 66 (4). pp. 850-854. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkq542 Full text not available from this repository.

Seifert, Karin; Pérez-Victoria, F Javier; Stettler, Marianne; Sánchez-Cañete, María P; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L; (2007) Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. International journal of antimicrobial agents, 30 (3). pp. 229-235. ISSN 0924-8579 DOI: https://doi.org/10.1016/j.ijantimicag.2007.05.007 Full text not available from this repository.

Voak, Andrew A; Gobalakrishnapillai, Vithurshaa; Seifert, Karin; Balczo, Edina; Hu, Longqin; Hall, Belinda S; Wilkinson, Shane R; (2013) An essential type I nitroreductase from Leishmania major can be used to activate leishmanicidal prodrugs. The Journal of biological chemistry, 288 (40). pp. 28466-28476. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M113.494781 Full text not available from this repository.

Voak, Andrew A; Seifert, Karin; Helsby, Nuala A; Wilkinson, Shane R; (2013) Evaluating aziridinyl nitrobenzamide compounds as leishmanicidal prodrugs. Antimicrobial agents and chemotherapy, 58 (1). pp. 370-377. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01459-13 Full text not available from this repository.

Walochnik, Julia; Duchêne, Michael; Seifert, Karin; Obwaller, Andreas; Hottkowitz, Thomas; Wiedermann, Gerhard; Eibl, Hansjörg; Aspöck, Horst; (2002) Cytotoxic activities of alkylphosphocholines against clinical isolates of Acanthamoeba spp. Antimicrobial agents and chemotherapy, 46 (3). pp. 695-701. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.46.3.695-701.2002 Full text not available from this repository.

Croft, Simon L; Seifert, Karin; Yardley, Vanessa; (2006) Current scenario of drug development for leishmaniasis. The Indian journal of medical research, 123 (3). pp. 399-410. ISSN 0971-5916 https://researchonline.lshtm.ac.uk/id/eprint/11722

Kaur, Harparkash; Seifert, Karin; Hawkes, Geoffrey E; Coumbarides, Gregory S; Alvar, Jorge; Croft, Simon L; (2015) Chemical and bioassay techniques to authenticate quality of the anti-leishmanial drug miltefosine. The American journal of tropical medicine and hygiene, 92 (6 Supp). pp. 31-38. ISSN 0002-9637 DOI: https://doi.org/10.4269/ajtmh.14-0586

Koniordou, Markela; Patterson, Stephen; Wyllie, Susan; Seifert, Karin; (2017) Snapshot Profiling of the Antileishmanial Potency of Lead Compounds and Drug Candidates against Intracellular Leishmania donovani Amastigotes, with a Focus on Human-Derived Host Cells. Antimicrobial agents and chemotherapy, 61 (3). e01228-e01216. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01228-16

Lamour, Sabrina D; Veselkov, Kirill A; Posma, Joram M; Giraud, Emilie; Rogers, Matthew E; Croft, Simon; Marchesi, Julian R; Holmes, Elaine; Seifert, Karin; Saric, Jasmina; (2014) Metabolic, immune, and gut microbial signals mount a systems response to Leishmania major infection. Journal of proteome research, 14 (1). pp. 318-329. ISSN 1535-3893 DOI: https://doi.org/10.1021/pr5008202

Meredith, Emma Louise; Kumar, Ambika; Konno, Aya; Szular, Joanna; Alsford, Sam; Seifert, Karin; Horn, David; Wilkinson, Shane R; (2017) Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs. Molecular microbiology, 106 (2). pp. 207-222. ISSN 0950-382X DOI: https://doi.org/10.1111/mmi.13767

Nicoletti, Salvatore; Seifert, Karin; Gilbert, Ian H; (2009) N-(2-hydroxypropyl)methacrylamide-amphotericin B (HPMA-AmB) copolymer conjugates as antileishmanial agents. International journal of antimicrobial agents, 33 (5). pp. 441-448. ISSN 0924-8579 DOI: https://doi.org/10.1016/j.ijantimicag.2008.10.013

Nicoletti, Salvatore; Seifert, Karin; Gilbert, Ian H; (2010) Water-soluble polymer-drug conjugates for combination chemotherapy against visceral leishmaniasis. Bioorganic & medicinal chemistry, 18 (7). pp. 2559-2565. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2010.02.043

Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C; (2015) Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. Gene therapy, 22 (8). pp. 628-635. ISSN 0969-7128 DOI: https://doi.org/10.1038/gt.2015.35

Salguero, Francisco J; Garcia-Jimenez, Waldo L; Lima, Isadora; Seifert, Karin; (2018) Histopathological and immunohistochemical characterisation of hepatic granulomas in Leishmania donovani-infected BALB/c mice: a time-course study. Parasites & vectors, 11 (1). 73-. ISSN 1756-3305 DOI: https://doi.org/10.1186/s13071-018-2624-z

Seifert, Karin; (2011) Structures, targets and recent approaches in anti-leishmanial drug discovery and development. The open medicinal chemistry journal, 5. pp. 31-39. ISSN 1874-1045 DOI: https://doi.org/10.2174/1874104501105010031

Voak, Andrew A; Standing, Joseph F; Sepúlveda, Nuno; Harris, Andy; Croft, Simon L; Seifert, Karin; (2018) Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages. The Journal of antimicrobial chemotherapy, 73 (5). pp. 1314-1323. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dky014