Alruwaili, Muharib; Elahi, Rubayet; van Schalkwyk, Donelly; Sutherland, Colin; Shapiro, Theresa; Prigge, Sean; Sullivan, David; (2023) Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum. The American journal of tropical medicine and hygiene, 108 (4). pp. 777-782. ISSN 0002-9637 DOI: https://doi.org/10.4269/ajtmh.22-0700

van Schalkwyk, Donelly A; Pratt, Sade; Nolder, Debbie; Stewart, Lindsay B; Liddy, Helen; Muwanguzi-Karugaba, Julian; Beshir, Khalid B; Britten, Dawn; Victory, Emma; Rogers, Claire; +7 more... Millard, James; Brown, Michael; Nabarro, Laura E; Taylor, Andrew; Young, Bernadette C; Chiodini, Peter L; Sutherland, Colin J; (2023) Treatment Failure in a UK Malaria Patient Harboring Genetically Variant Plasmodium falciparum From Uganda With Reduced In Vitro Susceptibility to Artemisinin and Lumefantrine. Clinical Infectious Diseases, 78 (2). pp. 445-452. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciad724

Abacha, Yabalu Z; Forkuo, Arnold Donkor; Gbedema, Stephen Y; Mittal, Nimisha; Ottilie, Sabine; Rocamora, Frances; Winzeler, Elizabeth A; van Schalkwyk, Donelly A; Kelly, John M; Taylor, Martin C; +9 more... Reader, Janette; Birkholtz, Lyn-Marie; Lisgarten, David R; Cockcroft, Jeremy K; Lisgarten, John N; Palmer, Rex A; Talbert, Rosemary C; Shnyder, Steven D; Wright, Colin W; (2022) Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer. Frontiers in Pharmacology, 13. 875647-. ISSN 1663-9812 DOI: https://doi.org/10.3389/fphar.2022.875647

Mohring, Franziska; van Schalkwyk, Donelly A; Henrici, Ryan C; Blasco, Benjamin; Leroy, Didier; Sutherland, Colin J; Moon, Robert W; (2022) Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs. mBio, 13 (5). e0117822-. ISSN 2150-7511 DOI: https://doi.org/10.1128/mbio.01178-22

Tan, Angelica F; Sakam, Sitti Saimah Binti; Rajahram, Giri S; William, Timothy; Abd Rachman Isnadi, Mohammad Faruq; Daim, Sylvia; Barber, Bridget E; Kho, Steven; Sutherland, Colin J; Anstey, Nicholas M; +3 more... Yerlikaya, Seda; van Schalkwyk, Donelly A; Grigg, Matthew J; (2022) Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum. Frontiers in cellular and infection microbiology, 12. 1023219-. ISSN 2235-2988 DOI: https://doi.org/10.3389/fcimb.2022.1023219

Grignard, Lynn; Nolder, Debbie; Sepulveda, Nuno; Berhane, Araia; Mihreteab, Selam; Kaaya, Robert; Phelan, Jody; Moser, Kara; van Schalkwyk, Donelly A; Campino, Susana; +7 more... Parr, Jonathan B; Juliano, Jonathan J; Chiodini, Peter; Cunningham, Jane; Sutherland, Colin J; Drakeley, Chris; Beshir, Khalid B; (2021) Corrigendum to 'A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections'. EBioMedicine, 65. 103261-. ISSN 2352-3964 DOI: https://doi.org/10.1016/j.ebiom.2021.103261

Miguel-Blanco, Celia; Murithi, James M; Benavente, Ernest Diez; Angrisano, Fiona; Sala, Katarzyna A; van Schalkwyk, Donelly A; Vanaerschot, Manu; Schwach, Frank; Fuchter, Matthew J; Billker, Oliver; +9 more... Sutherland, Colin J; Campino, Susana G; Clark, Taane G; Blagborough, Andrew M; Fidock, David A; Herreros, Esperanza; Gamo, Francisco Javier; Baum, Jake; Delves, Michael J; (2021) The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957. Scientific reports, 11 (1). 1888-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-021-81343-z

Nolder, Debbie; Stewart, Lindsay; Tucker, Julie; Ibrahim, Amy; Gray, Adam; Corrah, Tumena; Gallagher, Carmel; John, Laurence; O'Brien, Edel; Aggarwal, Dinesh; +8 more... Benavente, Ernest Diez; van Schalkwyk, Donelly; Henriques, Gisela; Sepúlveda, Nuno; Campino, Susana; Chiodini, Peter; Sutherland, Colin; Beshir, Khalid B; (2021) Failure of rapid diagnostic tests in Plasmodium falciparum malaria cases among travelers to the UK and Ireland: Identification and characterisation of the parasites. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 108. pp. 137-144. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2021.05.008

van Schalkwyk, Donelly A; Moon, Robert W; Duffey, Maëlle; Leroy, Didier; Sutherland, Colin J; (2021) Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium species. International journal for parasitology. Drugs and drug resistance, 17. pp. 5-11. ISSN 2211-3207 DOI: https://doi.org/10.1016/j.ijpddr.2021.07.002

Grignard, Lynn; Nolder, Debbie; Sepúlveda, Nuno; Berhane, Araia; Mihreteab, Selam; Kaaya, Robert; Phelan, Jody; Moser, Kara; van Schalkwyk, Donelly A; Campino, Susana; +7 more... Parr, Jonathan B; Juliano, Jonathan J; Chiodini, Peter; Cunningham, Jane; Sutherland, Colin J; Drakeley, Chris; Beshir, Khalid B; (2020) A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections. EBioMedicine, 55. 102757-. ISSN 2352-3964 DOI: https://doi.org/10.1016/j.ebiom.2020.102757 Item availability may be restricted.

Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; +4 more... Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J; (2020) The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. mBio, 11 (1). e02918-19. DOI: https://doi.org/10.1128/mBio.02918-19

Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; +4 more... Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J; (2020) The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. mBio, 11 (1). ISSN 2150-7511 DOI: https://doi.org/10.1128/mBio.02918-19

van Schalkwyk, Donelly A; Riscoe, Michael K; Pou, Sovitj; Winter, Rolf W; Nilsen, Aaron; Duffey, Maëlle; Moon, Robert W; Sutherland, Colin J; (2020) Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil. Antimicrobial Agents and Chemotherapy, 64 (5). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02549-19

van Schalkwyk, Donelly A; Riscoe, Michael K; Pou, Sovitj; Winter, Rolf W; Nilsen, Aaron; Duffey, Maëlle; Moon, Robert W; Sutherland, Colin J; (2020) Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil. Antimicrobial agents and chemotherapy, 64 (5). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02549-19

Henrici, Ryan C; van Schalkwyk, Donelly A; Sutherland, Colin J; (2019) Modification of pfap2μ and pfubp1 Markedly Reduces Ring-Stage Susceptibility of Plasmodium falciparum to Artemisinin In Vitro. Antimicrobial Agents and Chemotherapy, 64 (1). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01542-19

Henrici, Ryan C; van Schalkwyk, Donelly A; Sutherland, Colin J; (2019) Transient temperature fluctuations severely decrease P. falciparum susceptibility to artemisinin in vitro. International Journal for Parasitology: Drugs and Drug Resistance, 9. pp. 23-26. ISSN 2211-3207 DOI: https://doi.org/10.1016/j.ijpddr.2018.12.003

van Schalkwyk, Donelly A; Blasco, Benjamin; Davina Nuñez, Rocio; Liew, Jonathan WK; Amir, Amirah; Lau, Yee L; Leroy, Didier; Moon, Robert W; Sutherland, Colin J; (2019) Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum. International journal for parasitology. Drugs and drug resistance, 9. pp. 93-99. ISSN 2211-3207 DOI: https://doi.org/10.1016/j.ijpddr.2019.02.004

Cheaveau, James; Nguyen, Hong; Chow, Barbara; Marasinghe, Dewdunee; Mohon, Abu Naser; Yuan, Hong; Viana, Gisele; van Schalkwyk, Donelly; Church, Deirdre; Chan, Wilson; +1 more... Pillai, Dylan R; (2018) Clinical Validation of a Commercial LAMP Test for Ruling out Malaria in Returning Travelers: A Prospective Diagnostic Trial. OPEN FORUM INFECTIOUS DISEASES, 5 (11). ofy260-. ISSN 2328-8957 DOI: https://doi.org/10.1093/ofid/ofy260

Sutherland, Colin J; Lansdell, Paul; Sanders, Mandy; Muwanguzi, Julian; van Schalkwyk, Donelly A; Kaur, Harparkash; Nolder, Debbie; Tucker, Julie; Bennett, Hayley M; Otto, Thomas D; +5 more... Berriman, Matthew; Patel, Trupti A; Lynn, Roderick; Gkrania-Klotsas, Effrossyni; Chiodini, Peter L; (2017) pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom. Antimicrobial agents and chemotherapy, 61 (3). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02382-16

van Schalkwyk, Donelly A; Moon, Robert W; Blasco, Benjamin; Sutherland, Colin J; (2017) Comparison of the susceptibility of Plasmodium knowlesi and Plasmodium falciparum to antimalarial agents. The Journal of antimicrobial chemotherapy, 72 (11). pp. 3051-3058. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkx279

Hall, Zoe; Allan, Elizabeth Louise; van Schalkwyk, Donelly Andrew; van Wyk, Albert; Kaur, Harparkash; (2016) Degradation of Artemisinin-Based Combination Therapies Under Tropical Conditions. The American journal of tropical medicine and hygiene, 94 (5). pp. 993-1001. ISSN 0002-9637 DOI: https://doi.org/10.4269/ajtmh.15-0665

Xu, Gaolian; Nolder, Debbie; Reboud, Julien; Oguike, Mary C; van Schalkwyk, Donelly A; Sutherland, Colin J; Cooper, Jonathan M; (2016) Paper-Origami-Based Multiplexed Malaria Diagnostics from Whole Blood. Angewandte Chemie (International ed in English), 55 (49). pp. 15250-15253. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.201606060

van Schalkwyk, May CI; van Schalkwyk, Donelly A; (2016) We must go for gold in public health. BMJ (Clinical research ed), 354. i5138-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.i5138 Full text not available from this repository.

Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J; (2015) The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. Antimicrobial agents and chemotherapy, 59 (5). pp. 2540-2547. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.04067-14

van Schalkwyk, Donelly A; Nash, Megan N; Shafik, Sarah H; Summers, Robert L; Lehane, Adele M; Smith, Peter J; Martin, Rowena E; (2015) Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs. The Journal of infectious diseases, 213 (5). pp. 800-810. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiv509

van Schalkwyk, Donelly A; Sutherland, Colin J; (2015) Malaria resistance to non-artemisinin partner drugs: how to reACT. The Lancet infectious diseases, 15 (6). pp. 621-623. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(15)70080-0 Full text not available from this repository.

Chugh, Monika; Scheurer, Christian; Sax, Sibylle; Bilsland, Elizabeth; van Schalkwyk, Donelly A; Wicht, Kathryn J; Hofmann, Natalie; Sharma, Anil; Bashyam, Sridevi; Singh, Shivendra; +8 more... Oliver, Stephen G; Egan, Timothy J; Malhotra, Pawan; Sutherland, Colin J; Beck, Hans-Peter; Wittlin, Sergio; Spangenberg, Thomas; Ding, Xavier C; (2014) Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains. Antimicrobial agents and chemotherapy, 59 (2). pp. 1110-1118. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.03265-14 Full text not available from this repository.

Henriques, Gisela; Hallett, Rachel L; Beshir, Khalid B; Gadalla, Nahla B; Johnson, Rachel E; Burrow, Rebekah; van Schalkwyk, Donelly A; Sawa, Patrick; Omar, Sabah A; Clark, Taane G; +2 more... Bousema, Teun; Sutherland, Colin J; (2014) Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT. The Journal of infectious diseases, 210 (12). pp. 2001-2008. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiu358

van Schalkwyk, Donelly A; Burrow, Rebekah; Henriques, Gisela; Gadalla, Nahla B; Beshir, Khalid B; Hasford, Christian; Wright, Stephen G; Ding, Xavier C; Chiodini, Peter L; Sutherland, Colin J; (2013) Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers. Malaria journal, 12 (1). 320-. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-12-320