Items where Author is "Fletcher, HA"
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Number of items: 48.
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Chen, T;
Blanc, C;
Eder, AZ;
Prados-Rosales, R;
Souza, AC;
Kim, RS;
Glatman-Freedman, A;
Joe, M;
Bai, Y;
Lowary, TL;
+6 more...
Tanner, R;
Brennan, MJ;
Fletcher, HA;
McShane, H;
Casadevall, A;
Achkar, JM;
(2016)
Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction.
The Journal of infectious diseases, 214 (2).
pp. 300-10.
ISSN 0022-1899
DOI: https://doi.org/10.1093/infdis/jiw141
Full text not available from this repository.
Demissie, A;
Leyten, EM;
Abebe, M;
Wassie, L;
Aseffa, A;
Abate, G;
Fletcher, H;
Owiafe, P;
Hill, PC;
Brookes, R;
+8 more...
Rook, G;
Zumla, A;
Arend, SM;
Klein, M;
Ottenhoff, TH;
Andersen, P;
Doherty, TM;
VACSEL Study Group;
(2006)
Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis.
Clinical and vaccine immunology, 13 (2).
pp. 179-86.
ISSN 1556-6811
DOI: https://doi.org/10.1128/CVI.13.2.179-186.2006
Full text not available from this repository.
Fletcher, H;
(2015)
Profiling the host immune response to tuberculosis vaccines.
Vaccine.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2015.07.090
Full text not available from this repository.
Fletcher, HA;
(2018)
Systems approaches to correlates of protection and progression to TB disease.
Seminars in immunology.
ISSN 1044-5323
DOI: https://doi.org/10.1016/j.smim.2018.10.001
Full text not available from this repository.
Fletcher, HA;
Dockrell, HM;
(2016)
Human biomarkers: can they help us to develop a new tuberculosis vaccine?
Future microbiology, 11.
pp. 781-7.
ISSN 1746-0913
DOI: https://doi.org/10.2217/fmb.16.15
Full text not available from this repository.
Kaufmann, SH;
Fletcher, HA;
Guzman, CA;
Ottenhoff, TH;
(2015)
Introduction and section summaries.
Vaccine.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2015.04.078
Full text not available from this repository.
Kewcharoenwong, C;
Prabowo, SA;
Bancroft, GJ;
Fletcher, HA;
Lertmemongkolchai, G;
(2018)
Glibenclamide Reduces Primary Human Monocyte Functions Against Tuberculosis Infection by Enhancing M2 Polarization.
Frontiers in immunology, 9.
p. 2109.
ISSN 1664-3224
DOI: https://doi.org/10.3389/fimmu.2018.02109
Full text not available from this repository.
Naranbhai, V;
Moodley, D;
Chipato, T;
Stranix-Chibanda, L;
Nakabaiito, C;
Kamateeka, M;
Musoke, P;
Manji, K;
George, K;
Emel, LM;
+8 more...
Richardson, P;
Andrew, P;
Fowler, M;
Fletcher, H;
Mcshane, H;
Coovadia, HM;
Hill, AV;
for the HPTN 046 protocol team;
(2014)
The association between the ratio of monocytes: lymphocytes and risk of tuberculosis(TB) amongst HIV infected postpartum women.
Journal of acquired immune deficiency syndromes (1999).
ISSN 1525-4135
DOI: https://doi.org/10.1097/QAI.0000000000000353
Full text not available from this repository.
Rhodes, SJ;
Guedj, J;
Fletcher, HA;
Lindenstrøm, T;
Scriba, TJ;
Evans, TG;
Knight, GM;
White, RG;
(2018)
Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making.
NPJ Vaccines, 3.
p. 36.
ISSN 2059-0105
DOI: https://doi.org/10.1038/s41541-018-0075-3
Full text not available from this repository.
Schito, M;
Migliori, GB;
Fletcher, HA;
McNerney, R;
Centis, R;
D'Ambrosio, L;
Bates, M;
Kibiki, G;
Kapata, N;
Corrah, T;
+6 more...
Bomanji, J;
Vilaplana, C;
Johnson, D;
Mwaba, P;
Maeurer, M;
Zumla, A;
(2015)
Perspectives on Advances in Tuberculosis Diagnostics, Drugs, and Vaccines.
Clinical infectious diseases, 61 (suppl 3).
S102-S118.
ISSN 1058-4838
DOI: https://doi.org/10.1093/cid/civ609
Full text not available from this repository.
Public
Abubakar, I;
Lipman, M;
McHugh, TD;
Fletcher, H;
(2016)
Uniting to end the TB epidemic: advances in disease control from prevention to better diagnosis and treatment.
BMC medicine, 14 (1).
p. 47.
ISSN 1741-7015
DOI: https://doi.org/10.1186/s12916-016-0599-1
Andrews, JR;
Nemes, E;
Tameris, M;
Landry, BS;
Mahomed, H;
McClain, JB;
Fletcher, HA;
Hanekom, WA;
Wood, R;
McShane, H;
+2 more...
Scriba, TJ;
Hatherill, M;
(2017)
Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study.
The lancet Respiratory medicine, 5 (4).
pp. 282-290.
ISSN 2213-2600
DOI: https://doi.org/10.1016/S2213-2600(17)30060-7
Brennan, MJ;
Tanner, R;
Morris, S;
Scriba, TJ;
Achkar, JM;
Zelmer, A;
Hokey, D;
Izzo, A;
Sharpe, S;
Williams, A;
+6 more...
Penn-Nicholson, A;
Erasmus, M;
Stylianou, E;
Hoft, DF;
McShane, H;
Fletcher, HA;
(2017)
The Cross-species Mycobacterial Growth Inhibition Assay (MGIA) Project 2010-2014.
Clinical and vaccine immunology.
ISSN 1556-6811
DOI: https://doi.org/10.1128/CVI.00142-17
Cobelens, F;
Nagelkerke, N;
Fletcher, H;
(2018)
The convergent epidemiology of tuberculosis and human cytomegalovirus infection.
F1000Research, 7.
p. 280.
ISSN 2046-1402
DOI: https://doi.org/10.12688/f1000research.14184.1
Dowd, JB;
Fletcher, HA;
Boccia, D;
(2018)
Social determinants and BCG efficacy: a call for a socio-biological approach to TB prevention.
F1000Research, 7.
p. 224.
ISSN 2046-1402
DOI: https://doi.org/10.12688/f1000research.14085.1
Dunachie, S;
Hill, AV;
Fletcher, HA;
(2015)
Profiling the host response to malaria vaccination and malaria challenge.
Vaccine.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2015.07.107
Dutruel, C;
Thole, J;
Geels, M;
Mollenkopf, HJ;
Ottenhoff, T;
Guzman, CA;
Fletcher, HA;
Leroy, O;
Kaufmann, SH;
(2014)
TRANSVAC workshop on standardisation and harmonisation of analytical platforms for HIV, TB and malaria vaccines: 'How can big data help?'.
Vaccine.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2014.06.014
Fletcher, HA;
(2016)
Sleeping Beauty and the Story of the Bacille Calmette-Guérin Vaccine.
mBio, 7 (4).
ISSN 2150-7511
DOI: https://doi.org/10.1128/mBio.01370-16
Fletcher, HA;
Chatterjee, M;
Cooper, A;
Hussell, T;
Kaye, PM;
Prior, J;
Reljic, R;
Vermaak, S;
Vordermeier, M;
Williams, A;
+1 more...
McShane, H;
(2018)
VALIDATE: Exploiting the synergy between complex intracellular pathogens to expedite vaccine research and development for tuberculosis, leishmaniasis, melioidosis and leprosy.
F1000Research, 7.
p. 485.
ISSN 2046-1402
DOI: https://doi.org/10.12688/f1000research.14386.1
Fletcher, HA;
Filali-Mouhim, A;
Nemes, E;
Hawkridge, A;
Keyser, A;
Njikan, S;
Hatherill, M;
Scriba, TJ;
Abel, B;
Kagina, BM;
+32 more...
Veldsman, A;
Agudelo, NM;
Kaplan, G;
Hussey, GD;
Sekaly, RP;
Hanekom, WA;
BCG study team;
, COLLABORATORS;
Minnies, D;
Tanner, R;
Chung, CK;
Cameron, MJ;
Goulet, JP;
Gaujoux, R;
Hughes, J;
Gelderbloem, S;
Iloni, K;
Buchanan, M;
van der Merwe, L;
Burger, A;
Denation, L;
Mlanjeni, S;
Abrahams, S;
Shepherd, R;
Geldenhuys, M;
Seoighe, C;
Soares, A;
Gamieldien, H;
Sidibana, M;
Mahomed, H;
McShane, H;
Hill, AV;
(2016)
Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study.
BMC medicine, 14 (1).
p. 76.
ISSN 1741-7015
DOI: https://doi.org/10.1186/s12916-016-0617-3
Fletcher, HA;
Hawkridge, T;
McShane, H;
(2009)
A New Vaccine for Tuberculosis: The Challenges of Development and Deployment.
Journal of bioethical inquiry, 6 (2).
pp. 219-228.
ISSN 1176-7529
DOI: https://doi.org/10.1007/s11673-009-9153-6
Fletcher, HA;
Schrager, L;
(2016)
TB vaccine development and the End TB Strategy: importance and current status.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 110 (4).
pp. 212-8.
ISSN 0035-9203
DOI: https://doi.org/10.1093/trstmh/trw016
Fletcher, HA;
Snowden, MA;
Landry, B;
Rida, W;
Satti, I;
Harris, SA;
Matsumiya, M;
Tanner, R;
O'Shea, MK;
Dheenadhayalan, V;
+20 more...
Bogardus, L;
Stockdale, L;
Marsay, L;
Chomka, A;
Harrington-Kandt, R;
Manjaly-Thomas, ZR;
Naranbhai, V;
Stylianou, E;
Darboe, F;
Penn-Nicholson, A;
Nemes, E;
Hatheril, M;
Hussey, G;
Mahomed, H;
Tameris, M;
McClain, JB;
Evans, TG;
Hanekom, WA;
Scriba, TJ;
McShane, H;
(2016)
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Nature communications, 7.
p. 11290.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms11290
Griffiths, KL;
Pathan, AA;
Minassian, AM;
Sander, CR;
Beveridge, NE;
Hill, AV;
Fletcher, HA;
McShane, H;
(2011)
Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A.
PLoS One, 6 (8).
e23463.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0023463
Gupta-Wright, A;
Tomlinson, GS;
Rangaka, MX;
Fletcher, HA;
(2018)
World TB Day 2018: The Challenge of Drug Resistant Tuberculosis.
F1000Research, 7.
p. 217.
ISSN 2046-1402
DOI: https://doi.org/10.12688/f1000research.14088.1
Harris, SA;
Satti, I;
Matsumiya, M;
Stockdale, L;
Chomka, A;
Tanner, R;
O'Shea, MK;
Manjaly Thomas, ZR;
Tameris, M;
Mahomed, H;
+4 more...
Scriba, TJ;
Hanekom, WA;
Fletcher, HA;
McShane, H;
(2014)
Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A.
Clinical and vaccine immunology, 21 (7).
pp. 1005-11.
ISSN 1556-6811
DOI: https://doi.org/10.1128/CVI.00128-14
Jenjaroen, K;
Chumseng, S;
Sumonwiriya, M;
Ariyaprasert, P;
Chantratita, N;
Sunyakumthorn, P;
Hongsuwan, M;
Wuthiekanun, V;
Fletcher, HA;
Teparrukkul, P;
+3 more...
Limmathurotsakul, D;
Day, NP;
Dunachie, SJ;
(2015)
T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients.
PLoS neglected tropical diseases, 9 (10).
e0004152.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0004152
Khan, MS;
Fletcher, H;
London School of Hygiene and Tropical Medicine TB Centre Steerin;
Coker, R;
(2016)
Investments in tuberculosis research - what are the gaps?
BMC medicine, 14 (1).
p. 123.
ISSN 1741-7015
DOI: https://doi.org/10.1186/s12916-016-0644-0
Matsumiya, M;
Harris, SA;
Satti, I;
Stockdale, L;
Tanner, R;
O'Shea, MK;
Tameris, M;
Mahomed, H;
Hatherill, M;
Scriba, TJ;
+3 more...
Hanekom, WA;
McShane, H;
Fletcher, HA;
(2014)
Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
BMC infectious diseases, 14 (1).
p. 314.
ISSN 1471-2334
DOI: https://doi.org/10.1186/1471-2334-14-314
Matsumiya, M;
Satti, I;
Chomka, A;
Harris, SA;
Stockdale, L;
Meyer, J;
Fletcher, HA;
McShane, H;
(2014)
Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model.
The Journal of infectious diseases.
ISSN 0022-1899
DOI: https://doi.org/10.1093/infdis/jiu615
Naranbhai, V;
Fletcher, HA;
Tanner, R;
O'Shea, MK;
McShane, H;
Fairfax, BP;
Knight, JC;
Hill, AV;
(2015)
Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes.
EBioMedicine, 2 (11).
pp. 1619-1626.
ISSN 2352-3964
DOI: https://doi.org/10.1016/j.ebiom.2015.09.027
Naranbhai, V;
Kim, S;
Fletcher, H;
Cotton, MF;
Violari, A;
Mitchell, C;
Nachman, S;
McSherry, G;
McShane, H;
Hill, A;
+1 more...
Madhi, SA;
(2014)
The association between the ratio of monocytes:lymphocytes at age 3 months and risk of tuberculosis (TB) in the first two years of life.
BMC medicine, 12 (1).
p. 120.
ISSN 1741-7015
DOI: https://doi.org/10.1186/PREACCEPT-2435299671185919
Phillips, PP;
Fletcher, HA;
Abubakar, I;
Lipman, MC;
McHugh, TD;
(2016)
World TB Day 2016: an interview with leading experts in tuberculosis research.
BMC medicine, 14 (1).
p. 55.
ISSN 1741-7015
DOI: https://doi.org/10.1186/s12916-016-0591-9
Rhodes, SJ;
Knight, GM;
Fielding, K;
Scriba, TJ;
Pathan, AA;
McShane, H;
Fletcher, H;
White, RG;
(2015)
Individual-level factors associated with variation in mycobacterial-specific immune response: Gender and previous BCG vaccination status.
Tuberculosis (Edinburgh, Scotland), 96.
pp. 37-43.
ISSN 1472-9792
DOI: https://doi.org/10.1016/j.tube.2015.10.002
Rhodes, SJ;
Sarfas, C;
Knight, GM;
White, A;
Pathan, AA;
McShane, H;
Evans, TG;
Fletcher, H;
Sharpe, S;
White, RG;
(2017)
Predicting IFN-γ responses after BCG vaccination in humans from macaques: A proof-of-concept study of Immunostimulation/Immunodynamic modelling methods.
Clinical and vaccine immunology.
ISSN 1556-6811
DOI: https://doi.org/10.1128/CVI.00525-16
Rhodes, SJ;
Zelmer, A;
Knight, GM;
Prabowo, SA;
Stockdale, L;
Evans, TG;
Lindenstrøm, T;
White, RG;
Fletcher, H;
(2016)
The TB vaccine H56+IC31 dose-response curve is peaked not saturating: Data generation for new mathematical modelling methods to inform vaccine dose decisions.
Vaccine.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2016.10.060
Smith, SG;
Smits, K;
Joosten, SA;
van Meijgaarden, KE;
Satti, I;
Fletcher, HA;
Caccamo, N;
Dieli, F;
Mascart, F;
McShane, H;
+3 more...
Dockrell, HM;
Ottenhoff, TH;
TBVI TB Biomarker Working Group;
(2015)
Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines.
PloS one, 10 (9).
e0138042.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0138042
Stockdale, L;
Nash, S;
Nalwoga, A;
Painter, H;
Asiki, G;
Fletcher, H;
Newton, R;
(2018)
Human cytomegalovirus epidemiology and relationship to tuberculosis and cardiovascular disease risk factors in a rural Ugandan cohort.
PloS one, 13 (2).
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0192086
Tanner, R;
Kakalacheva, K;
Miller, E;
Pathan, AA;
Chalk, R;
Sander, CR;
Scriba, T;
Tameris, M;
Hawkridge, T;
Mahomed, H;
+5 more...
Hussey, G;
Hanekom, W;
Checkley, A;
McShane, H;
Fletcher, HA;
(2014)
Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A.
BMC infectious diseases, 14.
p. 660.
ISSN 1471-2334
DOI: https://doi.org/10.1186/s12879-014-0660-7
Tanner, R;
O'Shea, MK;
Fletcher, HA;
McShane, H;
(2016)
In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy.
Vaccine, 34 (39).
pp. 4656-4665.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2016.07.058
Tanner, R;
O'Shea, MK;
White, AD;
Müller, J;
Harrington-Kandt, R;
Matsumiya, M;
Dennis, MJ;
Parizotto, EA;
Harris, S;
Stylianou, E;
+6 more...
Naranbhai, V;
Bettencourt, P;
Drakesmith, H;
Sharpe, S;
Fletcher, HA;
McShane, H;
(2017)
The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.
Scientific reports, 7.
p. 43478.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep43478
Vainieri, ML;
Blagborough, AM;
MacLean, AL;
Haltalli, ML;
Ruivo, N;
Fletcher, HA;
Stumpf, MP;
Sinden, RE;
Celso, CL;
(2016)
Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points.
Open biology, 6 (6).
ISSN 2046-2441
DOI: https://doi.org/10.1098/rsob.160038
Voss, G;
Casimiro, D;
Neyrolles, O;
Williams, A;
Kaufmann, SHE;
McShane, H;
Hatherill, M;
Fletcher, HA;
(2018)
Progress and challenges in TB vaccine development.
F1000Research, 7.
p. 199.
ISSN 2046-1402
DOI: https://doi.org/10.12688/f1000research.13588.1
Wassie, L;
Demissie, A;
Aseffa, A;
Abebe, M;
Yamuah, L;
Tilahun, H;
Petros, B;
Rook, G;
Zumla, A;
Andersen, P;
+3 more...
Doherty, TM;
VACSEL Study Group, . (inc. Fletcher, H;
);
(2008)
Ex vivo cytokine mRNA levels correlate with changing clinical status of ethiopian TB patients and their contacts over time.
PLoS One, 3 (1).
e1522.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0001522
Zelmer, A;
Stockdale, L;
Prabowo, SA;
Cia, F;
Spink, N;
Gibb, M;
Eddaoudi, A;
Fletcher, HA;
(2018)
High monocyte to lymphocyte ratio is associated with impaired protection after subcutaneous administration of BCG in a mouse model of tuberculosis.
F1000Research, 7.
p. 296.
ISSN 2046-1402
DOI: https://doi.org/10.12688/f1000research.14239.1
Zelmer, A;
Tanner, R;
Stylianou, E;
Damelang, T;
Morris, S;
Izzo, A;
Williams, A;
Sharpe, S;
Pepponi, I;
Walker, B;
+4 more...
Hokey, DA;
McShane, H;
Brennan, M;
Fletcher, H;
(2016)
A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG-mediated protection in a murine model of tuberculosis.
BMC infectious diseases, 16.
p. 412.
ISSN 1471-2334
DOI: https://doi.org/10.1186/s12879-016-1751-4