Pertussis vaccine effectiveness in reducing clinical disease, transmissibility and proportion of cases with a positive culture after household exposure in Brazil.
Baptista, Paulo N;
Magalhães, Vera;
Rodrigues, Laura C;
Rocha, MariaAngela W;
Pimentel, Analíria M;
(2006)
Pertussis vaccine effectiveness in reducing clinical disease, transmissibility and proportion of cases with a positive culture after household exposure in Brazil.
The Pediatric infectious disease journal, 25 (9).
pp. 844-846.
ISSN 0891-3668
DOI: https://doi.org/10.1097/01.inf.0000232642.25495.95
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In household outbreaks of pertussis, children <5 years of age who received at least 3 doses of vaccine had 12% less clinical disease; vaccinated cases were 63% less culture-confirmed and transmitted infection to 62% fewer contacts. Three doses of pertussis vaccine are likely to decrease circulation of Bordetella pertussis by reducing the proportion of bacteriologically positive cases and transmissibility.