Lithothamnin A, the first bastadin-like metabolite from the red alga Lithothamnion fragilissimum.
Van Wyk, Albert WW;
Zuck, Karina M;
McKee, Tawnya C;
(2011)
Lithothamnin A, the first bastadin-like metabolite from the red alga Lithothamnion fragilissimum.
Journal of natural products, 74 (5).
pp. 1275-1280.
ISSN 0163-3864
DOI: https://doi.org/10.1021/np1006795
Permanent Identifier
Use this Digital Object Identifier when citing or linking to this resource.
Lithothamnin A (1) is a new bastadin-like metabolite and represents the first report of this class of molecules from the red alga Lithothamnion fragilissimum. Lithothamnin A contains several novel structural features that distinguish it from other bastadins. These unique structural features include novel aromatic substitution patterns and the presence of a meta-meta linkage between aromatic rings, in addition to the meta-para linkage seen in the bastadins. Lithothamnin A is modestly cytotoxic in a panel of six human tumor cell lines.
