Do patients who are infected with drug-resistant HIV have a different CD4 cell decline after seroconversion? An exploratory analysis in the UK Register of HIV Seroconverters

Bhaskaran, K; Pillay, D; Walker, AS; Fisher, M; Hawkins, D; Gilson, R; McLean, K; Porter, K; (2004) Do patients who are infected with drug-resistant HIV have a different CD4 cell decline after seroconversion? An exploratory analysis in the UK Register of HIV Seroconverters. AIDS (London, England), 18 (10). pp. 1471-3. ISSN 0269-9370 DOI: https://doi.org/10.1097/01.aids.0000131341.45795.33

Abstract

Using data from the UK Register of HIV Sero-converters, we compared the rate of CD4 cell decline in antiretroviral-naive individuals with and without evidence of transmitted drug resistance (TDR). Although there was a suggestion that CD4 cell decline in the first year after seroconversion was faster in those with TDR,there was no evidence of a difference in the rate of decline thereafter. The virological and host determinants of this possible phenomenon are worth further exploration.

Additional Information

Item Type	Article
Keywords	Adult, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes/ immunology/virology, Cohort Studies, Drug Resistance, Viral/ immunology, Female, HIV Infections/ drug therapy, HIV Seropositivity/immunology, Humans, Lymphopenia/virology, Male, Adult, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, immunology, virology, Cohort Studies, Drug Resistance, Viral, immunology, Female, HIV Infections, drug therapy, HIV Seropositivity, immunology, Humans, Lymphopenia, virology, Male
Faculty and Department	Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
PubMed ID	15199326
ISI	222641500016

Downloads

View details

Metrics & Citations

Google Scholar

Report this Record Edit item (admin only) View this record in elements

LSHTM LSHTM Research Online

Do patients who are infected with drug-resistant HIV have a different CD4 cell decline after seroconversion? An exploratory analysis in the UK Register of HIV Seroconverters

Permanent Identifier

Abstract

Additional Information

Share

Download

Downloads

Metrics & Citations

Google Scholar