Outcomes in HIV-infected patients who develop tuberculosis after starting antiretroviral treatment in Malawi.
Yu, JK-L;
Bong, C-N;
Chen, SC-C;
Dzimadzi, R;
Lu, D-Y;
Makombe, SD;
Schouten, EJ;
Kamoto, K;
Harries, AD;
(2008)
Outcomes in HIV-infected patients who develop tuberculosis after starting antiretroviral treatment in Malawi.
The international journal of tuberculosis and lung disease, 12 (6).
pp. 692-694.
ISSN 1027-3719
https://researchonline.lshtm.ac.uk/id/eprint/7307
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Use this permanent URL when citing or linking to this resource.
https://researchonline.lshtm.ac.uk/id/eprint/7307
Abstract
A retrospective review was conducted of patients starting antiretroviral treatment (ART) at Mzuzu Central Hospital, Malawi, to identify those who developed tuberculosis (TB) within 6 months of commencing ART and document their treatment outcomes. Of 2933 patients, 22 (0.75%) developed active TB, 17 (77%) of whom had commenced ART as a result of unexplained weight loss and/or fever. Of those who developed TB, 41% successfully completed anti-tuberculosis treatment, with lower survival probabilities than patients who did not develop TB. Easier methods are needed to diagnose TB in human immunodeficiency virus-infected patients and to prevent patients from developing TB while on ART.
