[Indoor radon exposure and lung cancer risk. Results of an epidemiological study carried out in France].
Baysson, H;
Tirmarche, M;
Tymen, G;
Gouva, S;
Caillaud, D;
Artus, JC;
Vergnenegre, A;
Ducloy, F;
Laurier, D;
(2005)
[Indoor radon exposure and lung cancer risk. Results of an epidemiological study carried out in France].
Revue des maladies respiratoires, 22 (4).
pp. 587-594.
ISSN 0761-8425
DOI: https://doi.org/10.1016/s0761-8425(05)85611-6
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INTRODUCTION: Several epidemiological studies have indicated an increased risk of lung cancer associated with indoor radon exposure. As part of a large European project, a hospital based case-control study was carried out in four regions of France: Auvergne, Brittany, Languedoc-Roussillon and Limousin. MATERIAL AND METHODS: Individual data on demographic characteristics, residential history, smoking and occupational exposures were collected during face-to-face interviews. Radon concentrations were measured in each dwelling occupied by the subject during the 30-year period prior to the interview. RESULTS: 486 cases and 984 controls were included in the study. After adjustment for age, sex, region, smoking history and occupational exposure, the risk of lung cancer increased by 4% per 100 Bq/m(3), when considering cumulative exposure in the 30 years prior to diagnosis. CONCLUSION: The study indicates a positive association between lung cancer risk and indoor radon exposure. The risk estimate per unit of exposure is in agreement with other recently published indoor case-control studies.