Increasing Birth-Dose Hepatitis B Vaccination in Nigeria: Qualitative Analysis of Data From a Crowdsourcing Open Call.

Shah, Sonam JORCID logo; Haque, RaynaORCID logo; Babatunde, Abdulhammed Opeyemi; Akinsolu, Folahanmi T; Afadapa, MariaORCID logo; Obodoechina, Nkiruka; Ogbeh, JosephORCID logo; Olusanya, Olufunto A; Ojo, TemitopeORCID logo; Alemu, Dawit; +14 more...Thompson, PeytonORCID logo; Falade-Nwulia, OluwaseunORCID logo; Day, SuzanneORCID logo; Wu, Dan; Lesi, Olufunmilayo; Nwaozuru, Ucheoma; Abike Gbaja-Biamila, Titilola; Salako, AbideenORCID logo; Zaidat Musa, Adesola; Idigbe, Ifeoma; Foley, KristieORCID logo; Iwelunmor, Juliet; Ezechi, Oliver C; and Tucker, Joseph DORCID logo (2025) Increasing Birth-Dose Hepatitis B Vaccination in Nigeria: Qualitative Analysis of Data From a Crowdsourcing Open Call. Open forum infectious diseases, 12 (7). ofaf400-. ISSN 2328-8957 DOI: 10.1093/ofid/ofaf400
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BACKGROUND: Despite World Health Organization and Nigerian recommendations for hepatitis B birth-dose (HepB-BD) vaccination, only one-third of Nigerian newborns receive timely HepB-BD vaccination, This study identified facilitators to increasing HepB-BD vaccination based on data from a crowdsourcing open call in Nigeria. METHODS: Our team conducted an open call across Nigeria for teams to submit ideas on how to increase HepB-BD vaccination. Independent judges evaluated the submissions based on predefined criteria. We analyzed textual data from the top 29 entries using iterative coding and thematic analysis within a socioecological model to identify priority facilitators. RESULTS: The open call received 362 total submissions, and 58.5% (215/362) of submissions were from women. Analysis of the top 29 submissions revealed 6 priority facilitators for increasing HepB-BD vaccination: (1) engage religious and healthcare leaders to educate pregnant women; (2) strengthen national policies for vaccination support and tracking; (3) counter misconceptions to promote attitude and behavior changes; (4) utilize rural infrastructure like town halls and radio programs to disseminate information; (5) translate educational materials into local languages like pidgin; and (6) organize financial or social incentives. CONCLUSIONS: Our crowdsourcing open call identified key facilitators and strategies for increasing HepB-BD vaccination among Nigerian newborns. The findings from this study can inform HepB-BD initiatives in Nigeria and other low- and middle-income countries.

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