Translational framework for implementation evaluation and research: implementation strategies derived from normalization process theory

Carl R May ORCID logo ; Alyson Hillis ; Bianca Albers ; Laura Desveaux ; Anthony Gilbert ; Melissa Girling ; Roman Kislov ; Anne MacFarlane ; Frances S Mair ; Sebastian Potthoff ; +2 more... Tim Rapley ; Tracy L Finch ; (2025) Translational framework for implementation evaluation and research: implementation strategies derived from normalization process theory. Implementation science, 20. p. 34. ISSN 1748-5908 DOI: 10.1186/s13012-025-01444-5
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Background: Implementation strategies are deliberate systematic actions used to support the uptake of innovations in health and social care. While widely used taxonomies such as ERIC and EPOC have emerged from consensus exercises, few implementation strategies are explicitly derived from theory and tested against empirical data. This study develops a taxonomy of implementation strategies grounded in Normalization Process Theory (NPT), an implementation theory that explains how new practices become embedded and sustained.

Methods: We conducted a qualitative evidence synthesis of studies that reported implementation projects informed by NPT. Studies were identified through citation tracking and database searches, screened using pre-specified criteria, and appraised for methodological quality. Using the NPT coding manual, we identified implementation mechanisms described in each study and translated these into candidate implementation strategies. These were then tested against all included studies through iterative qualitative content analysis.

Result: Searches led to 9,147 references, and we then eliminated 5,708 duplicates. After title and abstract screening a further 1,443 were eliminated. Full text screening was undertaken with 1,996 papers, and 1,411 of these were eliminated. This left 585 papers subjected to quality assessment, of which 522 were eliminated. Finally, 63 papers were included in the review. Qualitative analysis of included papers yielded 24 general strategies linked to NPT’s theoretical constructs and 96 micro-strategies representing four domains of implementation activity: leadership, information, empowerment, and service user involvement. Each strategy was explicitly linked to an NPT construct.

Conclusions: This study provides a theory-based and empirically grounded set of actionable implementation strategies. These are grounded in qualitative descriptions of implementation work. These strategies support practical decision-making across the planning, delivery, and sustainment phases of implementation, and offer context-sensitive guidance for adapting interventions to diverse settings. Unlike consensus-based taxonomies, these strategies are tied to observable mechanisms of action, enabling users to better understand and respond to the dynamic and socially organised nature of implementation. The NPT taxonomy of implementation strategies can support the design, tailoring, and operationalisation of implementation efforts across varied health and social care contexts.

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