Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placental Infection Is Associated With Massive Perivillous Fibrin Deposition at the Maternal-Fetal Interface: A Preliminary Study.
Esin
Kotiloglu-Karaa
;
Beatrix
Kele
;
Raghavendran
Kulasegaran-Shylini
;
Claire E
Broad
;
Dola
Owoyemi
;
Joanne
Martin
;
Graham
MacPhail
;
Stamatina
Iliodromiti
;
Anna
Riddell
;
Eliza
Alexander
;
+1 more...
Teresa
Cutino-Moguel
;
(2022)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placental Infection Is Associated With Massive Perivillous Fibrin Deposition at the Maternal-Fetal Interface: A Preliminary Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 75 (1).
e1176-e1179.
ISSN 1058-4838
DOI: 10.1093/cid/ciac173
We observed an increased frequency of massive perivillous fibrin deposition (MPFD) during the second coronavirus disease 2019 (COVID-19) pandemic wave dominated by the Alpha variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MPFD associated with 100% reverse transcription polymerase chain reaction (RT-PCR) positivity for SARS-CoV-2 and detection by immunohistochemistry. The Alpha variant was identified in all placentas with MPFD that could be sequenced.
Item Type | Article |
---|---|
Elements ID | 229486 |
Official URL | https://doi.org/10.1093/cid/ciac173 |
Date Deposited | 22 Jul 2025 13:55 |
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picture_as_pdf - Kotiloglu-karaa-etal-2022-sars-cov-2-placental-infection-is-associated-with-massive-perivillous-fibrin-deposition-at-the-maternal-fetal-interface.pdf
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subject - Accepted Version
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copyright - Available under Copyright the author(s)
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ORCID: https://orcid.org/0000-0003-1557-9126
ORCID: https://orcid.org/0000-0002-1726-4278