Endocrine effects of heat exposure and relevance to climate change.

Fadil M Hannan ORCID logo ; Melvin KS Leow ORCID logo ; Jason KW Lee ORCID logo ; Sari Kovats ORCID logo ; Taha Elajnaf ; Stephen H Kennedy ORCID logo ; Rajesh V Thakker ORCID logo ; (2024) Endocrine effects of heat exposure and relevance to climate change. Nature reviews. Endocrinology, 20 (11). pp. 673-684. ISSN 1759-5029 DOI: 10.1038/s41574-024-01017-4
Copy

Climate change is increasing both seasonal temperatures and the frequency and severity of heat extremes. As the endocrine system facilitates physiological adaptations to temperature changes, diseases with an endocrinological basis have the potential to affect thermoregulation and increase the risk of heat injury. The effect of climate change and associated high temperature exposure on endocrine axis development and function, and on the prevalence and severity of diseases associated with hormone deficiency or excess, is unclear. This Perspective summarizes current knowledge relating to the hormonal effects of heat exposure in species ranging from rodents to humans. We also describe the potential effect of high temperature exposures on patients with endocrine diseases. Finally, we highlight the need for more basic science, clinical and epidemiological research into the effects of heat on endocrine function and health; this research could enable the development of interventions for people most at risk, in the context of rising environmental temperatures.


picture_as_pdf
Hannan-etal-2024-Endocrine-effects-of-heat-exposure-and-relevance-to-climate-change.pdf
subject
Accepted Version
copyright
Available under Copyright the publishers

View Download

Atom BibTeX OpenURL ContextObject in Span Multiline CSV OpenURL ContextObject Dublin Core Dublin Core MPEG-21 DIDL Data Cite XML EndNote HTML Citation JSON MARC (ASCII) MARC (ISO 2709) METS MODS RDF+N3 RDF+N-Triples RDF+XML RIOXX2 XML Reference Manager Refer Simple Metadata ASCII Citation EP3 XML
Export

Downloads