Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician's perspective.

Kasibante, John; Rutakingirwa, Morris K; Kagimu, Enock; Ssebambulidde, Kenneth; Ellis, Jayne; Tugume, Lillian; Mpoza, Edward; Cresswell, Fiona; Meya, David B; (2020) Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician's perspective. JOURNAL OF CLINICAL TUBERCULOSIS AND OTHER MYCOBACTERIAL DISEASES, 20. 100180-. ISSN 2405-5794 DOI: https://doi.org/10.1016/j.jctube.2020.100180

Abstract

As part of the END TB strategy, the World Health organization (WHO) recommends provision of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB disease. Patients with HIV-associated cryptococcal meningitis are severely immunocompromised and therefore should be eligible for TPT. In this commentary we discuss the challenges associated with starting tuberculosis preventive therapy in patients with HIV associated cryptococcal meningitis in a clinical setting, we highlight the benefit, existing gaps and research opportunities of tuberculosis preventive therapy in this patient population.

Additional Information

Item Type	Article
Faculty and Department	Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID	32875123
Elements ID	158691
Official URL	http://dx.doi.org/10.1016/j.jctube.2020.100180

Download

Published Version Download

Filename: Kasibante-etal-2020-Tuberculosis-preventive-therapy-TPT-to-prevent-tuberculosis-co-infection-among-adults-with-HIV-associated-cryptococcal-meningitis-A-clinicians-perspective.pdf

Licence: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0

Download