Risk Stratification Using High-Sensitivity Cardiac Troponin T in Patients With Suspected Acute Coronary Syndrome.
Chapman, Andrew R;
Sandeman, Dennis;
Ferry, Amy V;
Stewart, Stacey;
Strachan, Fiona E;
Wereski, Ryan;
Bularga, Anda;
Anand, Atul;
Shah, Anoop SV;
Mills, Nicholas L;
(2020)
Risk Stratification Using High-Sensitivity Cardiac Troponin T in Patients With Suspected Acute Coronary Syndrome.
Journal of the American College of Cardiology (JACC), 75 (8).
pp. 985-987.
ISSN 0735-1097
DOI: https://doi.org/10.1016/j.jacc.2019.12.036
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High-sensitivity cardiac troponin assays allow the early recognition of myocardial injury, and they have facilitated the development of early rule-out pathways to identify patients who do not have acute myocardial infarction. Although international guidelines recommend using the sex-specific 99th centile from a healthy reference population as the diagnostic threshold for myocardial infarction, it is increasingly evident that the use of lower thresholds to risk-stratify patients and rule-out myocardial infarction at presentation is safer and more effective.