Clot Formation in Cardiopulmonary Bypass Circuit After Application of Factor XI Concentrate
Hulsman, Niels;
van der Meulen, Jan;
Talacua, Hanna;
Essoussi, Bachir;
Hermanns, Henning;
(2020)
Clot Formation in Cardiopulmonary Bypass Circuit After Application of Factor XI Concentrate.
Journal of Cardiothoracic and Vascular Anesthesia (JCVA), 34 (8).
pp. 2178-2180.
ISSN 1053-0770
DOI: https://doi.org/10.1053/j.jvca.2020.02.013
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THE MANAGEMENT of inherited or acquired coagulation disorders can be challenging during cardiac surgery with extracorporeal circulation. Although guidelines recommend preoperative supplementation of factor XI (FXI) with severe hemophilia C, there are certain risks involved with this strategy with the application of cardiac bypass.