Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions?

Andreia Vasconcelos ; Jonathan D King ; Cláudio Nunes-Alves ; Roy Anderson ; Daniel Argaw ; Maria-Gloria Basáñez ; Shakir Bilal ; David J Blok ; Seth Blumberg ; Anna Borlase ; +44 more... Oliver J Brady ORCID logo ; Raiha Browning ; Nakul Chitnis ; Luc E Coffeng ; Emily H Crowley ; Zulma M Cucunubá ; Derek AT Cummings ; Christopher Neil Davis ; Emma Louise Davis ; Matthew Dixon ; Andrew Dobson ; Louise Dyson ; Michael French ; Claudio Fronterre ; Emanuele Giorgi ; Ching-I Huang ; Saurabh Jain ; Ananthu James ; Sung Hye Kim ; Klodeta Kura ; Ana Lucianez ; Michael Marks ORCID logo ; Pamela Sabina Mbabazi ; Graham F Medley ORCID logo ; Edwin Michael ; Antonio Montresor ; Nyamai Mutono ; Thumbi S Mwangi ; Kat S Rock ; Martha-Idalí Saboyá-Díaz ; Misaki Sasanami ; Markus Schwehm ; Simon EF Spencer ; Ariktha Srivathsan ; Robert S Stawski ; Wilma A Stolk ; Samuel A Sutherland ; Louis-Albert Tchuem Tchuenté ; Sake J de Vlas ; Martin Walker ; Simon J Brooker ; T Déirdre Hollingsworth ; Anthony W Solomon ; Ibrahima Socé Fall ; (2024) Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions? Clinical infectious diseases, 78 (Suppl ). S83-S92. ISSN 1058-4838 DOI: 10.1093/cid/ciae082
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Over the past decade, considerable progress has been made in the control, elimination, and eradication of neglected tropical diseases (NTDs). Despite these advances, most NTD programs have recently experienced important setbacks; for example, NTD interventions were some of the most frequently and severely impacted by service disruptions due to the coronavirus disease 2019 (COVID-19) pandemic. Mathematical modeling can help inform selection of interventions to meet the targets set out in the NTD road map 2021-2030, and such studies should prioritize questions that are relevant for decision-makers, especially those designing, implementing, and evaluating national and subnational programs. In September 2022, the World Health Organization hosted a stakeholder meeting to identify such priority modeling questions across a range of NTDs and to consider how modeling could inform local decision making. Here, we summarize the outputs of the meeting, highlight common themes in the questions being asked, and discuss how quantitative modeling can support programmatic decisions that may accelerate progress towards the 2030 targets.


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