Comparison of Bivalent and Monovalent mRNA Vaccine Boosters.

Carlos KH Wong ORCID logo ; Kristy TK Lau ORCID logo ; Ivan CH Au ORCID logo ; Eric HY Lau ORCID logo ; Benjamin J Cowling ORCID logo ; (2023) Comparison of Bivalent and Monovalent mRNA Vaccine Boosters. Clinical infectious diseases, 78 (3). pp. 633-636. ISSN 1058-4838 DOI: 10.1093/cid/ciad519
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In this cohort study conducted in Hong Kong where both bivalent and monovalent formulations of BNT162b2 were available, there were no significant differences in the mortality or hospitalization between those who received bivalent and monovalent mRNA as second boosters. Bivalent and monovalent mRNA boosters appear equally protective against clinical outcomes.


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